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Best matches for guggulsterone:

Guggulsterone and Its Role in Chronic Diseases. Yamada T et al. Adv Exp Med Biol. (2016)

Z-Guggulsterone Produces Antidepressant-Like Effects in Mice through Activation of the BDNF Signaling Pathway. Liu FG et al. Int J Neuropsychopharmacol. (2017)

Guggulsterone for Chemoprevention of Cancer. Shishodia S et al. Curr Pharm Des. (2016)

Search results

Items: 1 to 20 of 210

1.

Calculus Bovis Sativus Improves Bile Acid Homeostasis via Farnesoid X Receptor-Mediated Signaling in Rats With Estrogen-Induced Cholestasis.

Xiang D, Yang J, Liu Y, He W, Zhang S, Li X, Zhang C, Liu D.

Front Pharmacol. 2019 Feb 1;10:48. doi: 10.3389/fphar.2019.00048. eCollection 2019.

2.

Guggulsterone Activates Adipocyte Beiging through Direct Effects on 3T3-L1 Adipocytes and Indirect Effects Mediated through RAW264.7 Macrophages.

Miller CN, Samuels JS, Azhar Y, Parmar A, Shashidharamurthy R, Rayalam S.

Medicines (Basel). 2019 Jan 31;6(1). pii: E22. doi: 10.3390/medicines6010022.

3.

Probucol ameliorates hepatic stellate cell activation and autophagy is associated with farnesoid X receptor.

Yang R, Hu Z, Zhang P, Wu S, Song Z, Shen X, Wei Z.

J Pharmacol Sci. 2019 Feb;139(2):120-128. doi: 10.1016/j.jphs.2018.12.005. Epub 2018 Dec 21.

4.

Guggulsterone, a farnesoid X receptor antagonist lowers plasma trimethylamine- N-oxide levels: An evidence from in vitro and in vivo studies.

Gautam A, Paudel YN, Abidin S, Bhandari U.

Hum Exp Toxicol. 2018 Dec 9:960327118817862. doi: 10.1177/0960327118817862. [Epub ahead of print]

PMID:
30526076
5.

Editor's Note: Guggulsterone Inhibits Osteoclastogenesis Induced by Receptor Activator of Nuclear Factor-κB Ligand and by Tumor Cells by Suppressing Nuclear Factor-κB Activation.

[No authors listed]

Clin Cancer Res. 2018 Sep 1;24(17):4347. doi: 10.1158/1078-0432.CCR-18-2525. No abstract available.

PMID:
30181392
6.

Editor's Note: Guggulsterone, a Farnesoid X Receptor Antagonist, Inhibits Constitutive and Inducible STAT3 Activation through Induction of a Protein Tyrosine Phosphatase SHP-1.

[No authors listed]

Cancer Res. 2018 Sep 1;78(17):5184. doi: 10.1158/0008-5472.CAN-18-2371. No abstract available.

PMID:
30181308
7.

Z-Guggulsterone attenuates astrocytes-mediated neuroinflammation after ischemia by inhibiting toll-like receptor 4 pathway.

Liu T, Liu M, Zhang T, Liu W, Xu H, Mu F, Ren D, Jia N, Li Z, Ding Y, Wen A, Li Y.

J Neurochem. 2018 Dec;147(6):803-815. doi: 10.1111/jnc.14583. Epub 2018 Nov 12.

PMID:
30168601
8.

Googling the Guggul (Commiphora and Boswellia) for Prevention of Chronic Diseases.

Kunnumakkara AB, Banik K, Bordoloi D, Harsha C, Sailo BL, Padmavathi G, Roy NK, Gupta SC, Aggarwal BB.

Front Pharmacol. 2018 Aug 6;9:686. doi: 10.3389/fphar.2018.00686. eCollection 2018. Review.

9.

In-vitro metabolism, CYP profiling and metabolite identification of E- and Z- guggulsterone, a potent hypolipidmic agent.

Chhonker YS, Chandasana H, Bala V, Mukkavilli R, Kumar D, Vangala S, Bhatta RS.

J Pharm Biomed Anal. 2018 Oct 25;160:202-211. doi: 10.1016/j.jpba.2018.06.047. Epub 2018 Jun 24.

PMID:
30099292
10.

Synthesis and biological evaluation of novel SIPI-7623 derivatives as farnesoid X receptor (FXR) antagonists.

Nian SY, Wang GP, Jiang ZL, Xiao Y, Huang MH, Zhou YH, Tan XD.

Mol Divers. 2018 Jul 4. doi: 10.1007/s11030-018-9843-2. [Epub ahead of print]

PMID:
29974364
11.

Farnesoid X Receptor Activation Enhances Transforming Growth Factor β-Induced Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma Cells.

Kainuma M, Takada I, Makishima M, Sano K.

Int J Mol Sci. 2018 Jun 28;19(7). pii: E1898. doi: 10.3390/ijms19071898.

12.

Activated-farnesoid X receptor (FXR) expressed in human sperm alters its fertilising ability.

Malivindi R, Santoro M, De Rose D, Panza S, Gervasi S, Rago V, Aquila S.

Reproduction. 2018 Sep;156(3):249-259. doi: 10.1530/REP-18-0203. Epub 2018 Jun 19.

PMID:
29921626
13.

Discovery of Natural Products as Novel and Potent FXR Antagonists by Virtual Screening.

Diao Y, Jiang J, Zhang S, Li S, Shan L, Huang J, Zhang W, Li H.

Front Chem. 2018 Apr 30;6:140. doi: 10.3389/fchem.2018.00140. eCollection 2018.

14.

Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor.

Gao X, Wang C, Ning C, Liu K, Wang X, Liu Z, Sun H, Ma X, Sun P, Meng Q.

Food Funct. 2018 May 23;9(5):2684-2694. doi: 10.1039/c8fo00107c.

PMID:
29721568
15.

Yangonin protects against cholestasis and hepatotoxity via activation of farnesoid X receptor in vivo and in vitro.

Gao X, Fu T, Wang C, Ning C, Liu K, Liu Z, Sun H, Ma X, Huo X, Yang X, Zou M, Meng Q.

Toxicol Appl Pharmacol. 2018 Jun 1;348:105-116. doi: 10.1016/j.taap.2018.04.015. Epub 2018 Apr 14.

PMID:
29660435
16.

A Review of Promising Natural Chemopreventive Agents for Head and Neck Cancer.

Crooker K, Aliani R, Ananth M, Arnold L, Anant S, Thomas SM.

Cancer Prev Res (Phila). 2018 Aug;11(8):441-450. doi: 10.1158/1940-6207.CAPR-17-0419. Epub 2018 Mar 30. Review.

PMID:
29602908
17.

Protective effects of guggulsterone against colitis are associated with the suppression of TREM-1 and modulation of macrophages.

Che X, Park KC, Park SJ, Kang YH, Jin HA, Kim JW, Seo DH, Kim DK, Kim TI, Kim WH, Kim SW, Cheon JH.

Am J Physiol Gastrointest Liver Physiol. 2018 Jul 1;315(1):G128-G139. doi: 10.1152/ajpgi.00027.2018. Epub 2018 Mar 15.

PMID:
29543509
18.

Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice.

Liu X, Guo GL, Kong B, Hilburn DB, Hubchak SC, Park S, LeCuyer B, Hsieh A, Wang L, Fang D, Green RM.

Hepatology. 2018 Jul;68(1):304-316. doi: 10.1002/hep.29815. Epub 2018 May 10.

PMID:
29377207
19.

Guggulsterone-releasing microspheres direct the differentiation of human induced pluripotent stem cells into neural phenotypes.

Agbay A, De La Vega L, Nixon G, Willerth S.

Biomed Mater. 2018 Feb 28;13(3):034104. doi: 10.1088/1748-605X/aaaa77.

PMID:
29368696
20.

Computational discovery and experimental verification of farnesoid X receptor agonist auraptene to protect against cholestatic liver injury.

Gao X, Fu T, Wang C, Ning C, Kong Y, Liu Z, Sun H, Ma X, Liu K, Meng Q.

Biochem Pharmacol. 2017 Dec 15;146:127-138. doi: 10.1016/j.bcp.2017.09.016. Epub 2017 Oct 4.

PMID:
28987596

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