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Items: 1 to 20 of 54


Talin Autoinhibition Regulates Cell-ECM Adhesion Dynamics and Wound Healing In Vivo.

Haage A, Goodwin K, Whitewood A, Camp D, Bogutz A, Turner CT, Granville DJ, Lefebvre L, Plotnikov S, Goult BT, Tanentzapf G.

Cell Rep. 2018 Nov 27;25(9):2401-2416.e5. doi: 10.1016/j.celrep.2018.10.098.


Calcium-mediated Protein Folding and Stabilization of Salmonella Biofilm-associated Protein A.

Guttula D, Yao M, Baker K, Yang L, Goult BT, Doyle PS, Yan J.

J Mol Biol. 2018 Nov 16. pii: S0022-2836(18)30817-9. doi: 10.1016/j.jmb.2018.11.014. [Epub ahead of print]


Direct binding of Talin to Rap1 is required for cell-ECM adhesion in Drosophila.

Camp D, Haage A, Solianova V, Castle WM, Xu QA, Lostchuck E, Goult BT, Tanentzapf G.

J Cell Sci. 2018 Nov 16. pii: jcs.225144. doi: 10.1242/jcs.225144. [Epub ahead of print]


Talin as a mechanosensitive signaling hub.

Goult BT, Yan J, Schwartz MA.

J Cell Biol. 2018 Nov 5;217(11):3776-3784. doi: 10.1083/jcb.201808061. Epub 2018 Sep 25. Review.


Kindlin-1 Regulates Epidermal Growth Factor Receptor Signaling.

Michael M, Begum R, Chan GK, Whitewood AJ, Matthews DR, Goult BT, McGrath JA, Parsons M.

J Invest Dermatol. 2018 Sep 21. pii: S0022-202X(18)32587-9. doi: 10.1016/j.jid.2018.08.020. [Epub ahead of print]


Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation.

Lagarrigue F, Gingras AR, Paul DS, Valadez AJ, Cuevas MN, Sun H, Lopez-Ramirez MA, Goult BT, Shattil SJ, Bergmeier W, Ginsberg MH.

Blood Adv. 2018 Sep 25;2(18):2358-2368. doi: 10.1182/bloodadvances.2018020487.


ProLIF - quantitative integrin protein-protein interactions and synergistic membrane effects on proteoliposomes.

De Franceschi N, Miihkinen M, Hamidi H, Alanko J, Mai A, Picas L, Guzmán C, Lévy D, Mattjus P, Goult BT, Goud B, Ivaska J.

J Cell Sci. 2018 Aug 20;132(4). pii: jcs214270. doi: 10.1242/jcs.214270.


The tale of two talins - two isoforms to fine-tune integrin signalling.

Gough RE, Goult BT.

FEBS Lett. 2018 Jun;592(12):2108-2125. doi: 10.1002/1873-3468.13081. Epub 2018 May 18. Review.


Chlamydial virulence factor TarP mimics talin to disrupt the talin-vinculin complex.

Whitewood AJ, Singh AK, Brown DG, Goult BT.

FEBS Lett. 2018 May;592(10):1751-1760. doi: 10.1002/1873-3468.13074. Epub 2018 May 15.


The Structural Basis of Calcium-Dependent Inactivation of the Transient Receptor Potential Vanilloid 5 Channel.

Bokhovchuk FM, Bate N, Kovalevskaya NV, Goult BT, Spronk CAEM, Vuister GW.

Biochemistry. 2018 May 8;57(18):2623-2635. doi: 10.1021/acs.biochem.7b01287. Epub 2018 Apr 20.


A Novel Mechanism for Calmodulin-Dependent Inactivation of Transient Receptor Potential Vanilloid 6.

Bate N, Caves RE, Skinner SP, Goult BT, Basran J, Mitcheson JS, Vuister GW.

Biochemistry. 2018 May 8;57(18):2611-2622. doi: 10.1021/acs.biochem.7b01286. Epub 2018 Apr 13.


Investigation of the Filamin A-Dependent Mechanisms of Tissue Factor Incorporation into Microvesicles.

Collier MEW, Ettelaie C, Goult BT, Maraveyas A, Goodall AH.

Thromb Haemost. 2017 Nov;117(11):2034-2044. doi: 10.1160/TH17-01-0009. Epub 2017 Nov 30.


Talin2-mediated traction force drives matrix degradation and cell invasion.

Qi L, Jafari N, Li X, Chen Z, Li L, Hytönen VP, Goult BT, Zhan CG, Huang C.

J Cell Sci. 2016 Oct 1;129(19):3661-3674.


Correction: Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity.

Kumar A, Ouyang M, Van den Dries K, McGhee EJ, Tanaka K, Anderson MD, Groisman A, Goult BT, Anderson KI, Schwartz MA.

J Cell Biol. 2016 Jul 18;214(2):231. doi: 10.1083/jcb.20151001207062016c. No abstract available.


Talin-KANK1 interaction controls the recruitment of cortical microtubule stabilizing complexes to focal adhesions.

Bouchet BP, Gough RE, Ammon YC, van de Willige D, Post H, Jacquemet G, Altelaar AM, Heck AJ, Goult BT, Akhmanova A.

Elife. 2016 Jul 13;5. pii: e18124. doi: 10.7554/eLife.18124.


The mechanical response of talin.

Yao M, Goult BT, Klapholz B, Hu X, Toseland CP, Guo Y, Cong P, Sheetz MP, Yan J.

Nat Commun. 2016 Jul 7;7:11966. doi: 10.1038/ncomms11966.


LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex.

Zacharchenko T, Qian X, Goult BT, Jethwa D, Almeida TB, Ballestrem C, Critchley DR, Lowy DR, Barsukov IL.

Structure. 2016 Jul 6;24(7):1130-41. doi: 10.1016/j.str.2016.04.016. Epub 2016 Jun 2.


Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity.

Kumar A, Ouyang M, Van den Dries K, McGhee EJ, Tanaka K, Anderson MD, Groisman A, Goult BT, Anderson KI, Schwartz MA.

J Cell Biol. 2016 May 9;213(3):371-83. doi: 10.1083/jcb.201510012. Erratum in: J Cell Biol. 2016 Jul 18;214(2):231.


Vinculin controls talin engagement with the actomyosin machinery.

Atherton P, Stutchbury B, Wang DY, Jethwa D, Tsang R, Meiler-Rodriguez E, Wang P, Bate N, Zent R, Barsukov IL, Goult BT, Critchley DR, Ballestrem C.

Nat Commun. 2015 Dec 4;6:10038. doi: 10.1038/ncomms10038.


A direct interaction between fascin and microtubules contributes to adhesion dynamics and cell migration.

Villari G, Jayo A, Zanet J, Fitch B, Serrels B, Frame M, Stramer BM, Goult BT, Parsons M.

J Cell Sci. 2015 Dec 15;128(24):4601-14. doi: 10.1242/jcs.175760. Epub 2015 Nov 5.

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