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Items: 1 to 20 of 364

1.

A Mitochondrial Checkpoint in Autoimmune Disease.

Weyand CM, Goronzy JJ.

Cell Metab. 2018 Aug 7;28(2):185-186. doi: 10.1016/j.cmet.2018.07.014.

PMID:
30089238
2.

Regulation of miR-181a expression in T cell aging.

Ye Z, Li G, Kim C, Hu B, Jadhav RR, Weyand CM, Goronzy JJ.

Nat Commun. 2018 Aug 3;9(1):3060. doi: 10.1038/s41467-018-05552-3.

3.

Matrix Metalloprotease-9 (MMP-9)-Producing Monocytes Enable T Cells to Invade the Vessel Wall and Cause Vasculitis.

Watanabe R, Maeda T, Zhang H, Berry GJ, Zeisbrich M, Brockett RD, Greenstein AE, Tian L, Goronzy J, Weyand CM.

Circ Res. 2018 Jul 3. pii: CIRCRESAHA.118.313206. doi: 10.1161/CIRCRESAHA.118.313206. [Epub ahead of print]

PMID:
29970365
4.

Epigenetics of T cell aging.

Goronzy JJ, Hu B, Kim C, Jadhav RR, Weyand CM.

J Leukoc Biol. 2018 Jun 27. doi: 10.1002/JLB.1RI0418-160R. [Epub ahead of print] Review.

PMID:
29947427
5.

Vaccination programs for older adults in an era of demographic change.

Doherty TM, Connolly MP, Del Giudice G, Flamaing J, Goronzy JJ, Grubeck-Loebenstein B, Lambert PH, Maggi S, McElhaney JE, Nagai H, Schaffner W, Schmidt-Ott R, Walsh E, Di Pasquale A.

Eur Geriatr Med. 2018;9(3):289-300. doi: 10.1007/s41999-018-0040-8. Epub 2018 Mar 19. Review.

6.

Redox-sensitive signaling in inflammatory T cells and in autoimmune disease.

Weyand CM, Shen Y, Goronzy JJ.

Free Radic Biol Med. 2018 Mar 7. pii: S0891-5849(18)30107-2. doi: 10.1016/j.freeradbiomed.2018.03.004. [Epub ahead of print] Review.

PMID:
29524605
7.

[Periacetabular osteotomy-what influence does age have on patient-relevant results? : A prospective 5‑year investigation].

Franken L, Thielemann F, Postler A, Blum S, Hartmann A, Günther KP, Goronzy J.

Orthopade. 2018 Mar;47(3):228-237. doi: 10.1007/s00132-017-3523-2. German.

PMID:
29435594
8.

Hypermetabolic macrophages in rheumatoid arthritis and coronary artery disease due to glycogen synthase kinase 3b inactivation.

Zeisbrich M, Yanes RE, Zhang H, Watanabe R, Li Y, Brosig L, Hong J, Wallis BB, Giacomini JC, Assimes TL, Goronzy JJ, Weyand CM.

Ann Rheum Dis. 2018 Jul;77(7):1053-1062. doi: 10.1136/annrheumdis-2017-212647. Epub 2018 Feb 3.

PMID:
29431119
9.

Fighting against a protean enemy: immunosenescence, vaccines, and healthy aging.

Del Giudice G, Goronzy JJ, Grubeck-Loebenstein B, Lambert PH, Mrkvan T, Stoddard JJ, Doherty TM.

NPJ Aging Mech Dis. 2017 Dec 21;4:1. doi: 10.1038/s41514-017-0020-0. eCollection 2018.

10.

Inhibition of JAK-STAT Signaling Suppresses Pathogenic Immune Responses in Medium and Large Vessel Vasculitis.

Zhang H, Watanabe R, Berry GJ, Tian L, Goronzy JJ, Weyand CM.

Circulation. 2018 May 1;137(18):1934-1948. doi: 10.1161/CIRCULATIONAHA.117.030423. Epub 2017 Dec 18.

PMID:
29254929
11.

Origin and differentiation of human memory CD8 T cells after vaccination.

Akondy RS, Fitch M, Edupuganti S, Yang S, Kissick HT, Li KW, Youngblood BA, Abdelsamed HA, McGuire DJ, Cohen KW, Alexe G, Nagar S, McCausland MM, Gupta S, Tata P, Haining WN, McElrath MJ, Zhang D, Hu B, Greenleaf WJ, Goronzy JJ, Mulligan MJ, Hellerstein M, Ahmed R.

Nature. 2017 Dec 21;552(7685):362-367. doi: 10.1038/nature24633. Epub 2017 Dec 13.

12.

DNA damage, metabolism and aging in pro-inflammatory T cells: Rheumatoid arthritis as a model system.

Li Y, Goronzy JJ, Weyand CM.

Exp Gerontol. 2018 May;105:118-127. doi: 10.1016/j.exger.2017.10.027. Epub 2017 Nov 8. Review.

PMID:
29101015
13.

The immunoinhibitory PD-1/PD-L1 pathway in inflammatory blood vessel disease.

Weyand CM, Berry GJ, Goronzy JJ.

J Leukoc Biol. 2018 Mar;103(3):565-575. doi: 10.1189/jlb.3MA0717-283. Epub 2017 Dec 29.

PMID:
28848042
14.

Metabolic control of the scaffold protein TKS5 in tissue-invasive, proinflammatory T cells.

Shen Y, Wen Z, Li Y, Matteson EL, Hong J, Goronzy JJ, Weyand CM.

Nat Immunol. 2017 Sep;18(9):1025-1034. doi: 10.1038/ni.3808. Epub 2017 Jul 24.

15.

The microvascular niche instructs T cells in large vessel vasculitis via the VEGF-Jagged1-Notch pathway.

Wen Z, Shen Y, Berry G, Shahram F, Li Y, Watanabe R, Liao YJ, Goronzy JJ, Weyand CM.

Sci Transl Med. 2017 Jul 19;9(399). pii: eaal3322. doi: 10.1126/scitranslmed.aal3322.

16.

Immune Checkpoint Function of CD85j in CD8 T Cell Differentiation and Aging.

Gustafson CE, Qi Q, Hutter-Saunders J, Gupta S, Jadhav R, Newell E, Maecker H, Weyand CM, Goronzy JJ.

Front Immunol. 2017 Jun 14;8:692. doi: 10.3389/fimmu.2017.00692. eCollection 2017.

17.

Pyruvate controls the checkpoint inhibitor PD-L1 and suppresses T cell immunity.

Watanabe R, Shirai T, Namkoong H, Zhang H, Berry GJ, Wallis BB, Schaefgen B, Harrison DG, Tremmel JA, Giacomini JC, Goronzy JJ, Weyand CM.

J Clin Invest. 2017 Jun 30;127(7):2725-2738. doi: 10.1172/JCI92167. Epub 2017 Jun 12.

18.

Metabolic signatures of T-cells and macrophages in rheumatoid arthritis.

Weyand CM, Zeisbrich M, Goronzy JJ.

Curr Opin Immunol. 2017 Jun;46:112-120. doi: 10.1016/j.coi.2017.04.010. Epub 2017 May 21. Review.

19.

Epigenomics of human CD8 T cell differentiation and aging.

Moskowitz DM, Zhang DW, Hu B, Le Saux S, Yanes RE, Ye Z, Buenrostro JD, Weyand CM, Greenleaf WJ, Goronzy JJ.

Sci Immunol. 2017 Feb;2(8). pii: eaag0192. doi: 10.1126/sciimmunol.aag0192. Epub 2017 Feb 17.

20.

Immunometabolism in early and late stages of rheumatoid arthritis.

Weyand CM, Goronzy JJ.

Nat Rev Rheumatol. 2017 May;13(5):291-301. doi: 10.1038/nrrheum.2017.49. Epub 2017 Mar 31. Review.

PMID:
28360422

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