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Items: 16


Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration.

Krishnaswamy JK, Singh A, Gowthaman U, Wu R, Gorrepati P, Sales Nascimento M, Gallman A, Liu D, Rhebergen AM, Calabro S, Xu L, Ranney P, Srivastava A, Ranson M, Gorham JD, McCaw Z, Kleeberger SR, Heinz LX, Müller AC, Bennett KL, Superti-Furga G, Henao-Mejia J, Sutterwala FS, Williams A, Flavell RA, Eisenbarth SC.

Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):3056-61. doi: 10.1073/pnas.1501554112.


Appropriate development of the liver Treg compartment is modulated by the microbiota and requires TGF-β and MyD88.

Maria A, English KA, Gorham JD.

J Immunol Res. 2014;2014:279736. doi: 10.1155/2014/279736.


The microbiota regulates susceptibility to Fas-mediated acute hepatic injury.

Celaj S, Gleeson MW, Deng J, O'Toole GA, Hampton TH, Toft MF, Morrison HG, Sogin ML, Putra J, Suriawinata AA, Gorham JD.

Lab Invest. 2014 Sep;94(9):938-49. doi: 10.1038/labinvest.2014.93.


1 + 1 = 3: Development and validation of a SNP-based algorithm to identify genetic contributions from three distinct inbred mouse strains.

Gorham JD, Ranson MS, Smith JC, Gorham BJ, Muirhead KA.

J Biomol Tech. 2012 Dec;23(4):136-46. doi: 10.7171/jbt.12-2304-004.


Liver inflammation in a mouse model of Th1 hepatitis despite the absence of invariant NKT cells or the Th1 chemokine receptors CXCR3 and CCR5.

Cripps JG, Celaj S, Burdick M, Strieter RM, Gorham JD.

Lab Invest. 2012 Oct;92(10):1461-71. doi: 10.1038/labinvest.2012.104.


MDSC in autoimmunity.

Cripps JG, Gorham JD.

Int Immunopharmacol. 2011 Jul;11(7):789-93. doi: 10.1016/j.intimp.2011.01.026. Review.


Type 1 T helper cells induce the accumulation of myeloid-derived suppressor cells in the inflamed Tgfb1 knockout mouse liver.

Cripps JG, Wang J, Maria A, Blumenthal I, Gorham JD.

Hepatology. 2010 Oct;52(4):1350-9. doi: 10.1002/hep.23841.


Bone marrow stromal cells use TGF-beta to suppress allergic responses in a mouse model of ragweed-induced asthma.

Nemeth K, Keane-Myers A, Brown JM, Metcalfe DD, Gorham JD, Bundoc VG, Hodges MG, Jelinek I, Madala S, Karpati S, Mezey E.

Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5652-7. doi: 10.1073/pnas.0910720107. Erratum in: Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):8041. Gorham, Jared D [corrected to Gorham, James D]; Bundoc, Victor G [corrected to Bundoc, Virgilio G].


The role of Ifng in alterations in liver gene expression in a mouse model of fulminant autoimmune hepatitis.

Milks MW, Cripps JG, Lin H, Wang J, Robinson RT, Sargent JL, Whitfield ML, Gorham JD.

Liver Int. 2009 Oct;29(9):1307-15. doi: 10.1111/j.1478-3231.2009.02028.x.


End-organ damage in a mouse model of fulminant liver inflammation requires CD4+ T cell production of IFN-gamma but is independent of Fas.

Robinson RT, Wang J, Cripps JG, Milks MW, English KA, Pearson TA, Gorham JD.

J Immunol. 2009 Mar 1;182(5):3278-84. doi: 10.4049/jimmunol.0803417.


Enhanced efficacy and reduced toxicity of multifactorial adjuvants compared with unitary adjuvants as cancer vaccines.

Ahonen CL, Wasiuk A, Fuse S, Turk MJ, Ernstoff MS, Suriawinata AA, Gorham JD, Kedl RM, Usherwood EJ, Noelle RJ.

Blood. 2008 Mar 15;111(6):3116-25. doi: 10.1182/blood-2007-09-114371.


The Ets transcription factor ERM is Th1-specific and induced by IL-12 through a Stat4-dependent pathway.

Ouyang W, Jacobson NG, Bhattacharya D, Gorham JD, Fenoglio D, Sha WC, Murphy TL, Murphy KM.

Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3888-93.


Genetic mapping of a murine locus controlling development of T helper 1/T helper 2 type responses.

Gorham JD, Güler ML, Steen RG, Mackey AJ, Daly MJ, Frederick K, Dietrich WF, Murphy KM.

Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12467-72.


Lipoteichoic acid preparations of gram-positive bacteria induce interleukin-12 through a CD14-dependent pathway.

Cleveland MG, Gorham JD, Murphy TL, Tuomanen E, Murphy KM.

Infect Immun. 1996 Jun;64(6):1906-12.


A nerve growth factor-regulated messenger RNA encodes a new intermediate filament protein.

Leonard DG, Gorham JD, Cole P, Greene LA, Ziff EB.

J Cell Biol. 1988 Jan;106(1):181-93.

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