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Antiosteoporotic Activity of Genistein Aglycone in Postmenopausal Women: Evidence from a Post-Hoc Analysis of a Multicenter Randomized Controlled Trial.

Arcoraci V, Atteritano M, Squadrito F, D'Anna R, Marini H, Santoro D, Minutoli L, Messina S, Altavilla D, Bitto A.

Nutrients. 2017 Feb 22;9(2). pii: E179. doi: 10.3390/nu9020179.


The effect of genistein on glucose control and insulin sensitivity in postmenopausal women: A meta-analysis.

Liu Y, Li J, Wang T, Wang Y, Zhao L, Fang Y.

Maturitas. 2017 Mar;97:44-52. doi: 10.1016/j.maturitas.2016.12.004. Epub 2016 Dec 28. Review.


Ethylene Induced a High Accumulation of Dietary Isoflavones and Expression of Isoflavonoid Biosynthetic Genes in Soybean (Glycine max) Leaves.

Yuk HJ, Song YH, Curtis-Long MJ, Kim DW, Woo SG, Lee YB, Uddin Z, Kim CY, Park KH.

J Agric Food Chem. 2016 Oct 5;64(39):7315-7324. Epub 2016 Sep 27.


Does genistein lower plasma lipids and homocysteine levels in postmenopausal women? A meta-analysis.

Li J, Liu Y, Wang T, Zhao L, Feng W.

Climacteric. 2016 Oct;19(5):440-7. doi: 10.1080/13697137.2016.1194388. Epub 2016 Jun 24.


Phase II metabolism of the soy isoflavones genistein and daidzein in humans, rats and mice: a cross-species and sex comparison.

Soukup ST, Helppi J, Müller DR, Zierau O, Watzl B, Vollmer G, Diel P, Bub A, Kulling SE.

Arch Toxicol. 2016 Jun;90(6):1335-47. doi: 10.1007/s00204-016-1663-5. Epub 2016 Feb 2. Erratum in: Arch Toxicol. 2016 Jun;90(6):1349.


Urinary isoflavonoids and risk of type 2 diabetes: a prospective investigation in US women.

Ding M, Franke AA, Rosner BA, Giovannucci E, van Dam RM, Tworoger SS, Hu FB, Sun Q.

Br J Nutr. 2015 Nov 28;114(10):1694-701. doi: 10.1017/S0007114515003359. Epub 2015 Sep 15.


Impact of equol-producing capacity and soy-isoflavone profiles of supplements on bone calcium retention in postmenopausal women: a randomized crossover trial.

Pawlowski JW, Martin BR, McCabe GP, McCabe L, Jackson GS, Peacock M, Barnes S, Weaver CM.

Am J Clin Nutr. 2015 Sep;102(3):695-703. doi: 10.3945/ajcn.114.093906. Epub 2015 Aug 5.


Effects of the Chinese Herbal Formulation (Liu Wei Di Huang Wan) on the Pharmacokinetics of Isoflavones in Postmenopausal Women.

Limopasmanee W, Chansakaow S, Rojanasthien N, Manorot M, Sangdee C, Teekachunhatean S.

Biomed Res Int. 2015;2015:902702. doi: 10.1155/2015/902702. Epub 2015 Jun 4.


Evaluation of Levothyroxine Bioavailability after Oral Administration of a Fixed Combination of Soy Isoflavones in Post-menopausal Female Volunteers.

Persiani S, Sala F, Manzotti C, Colovic M, Zangarini M, Donazzolo Y, Barbetta B, Vitalini C, Giacovelli G, Benvenuti C, Rovati LC.

Drug Res (Stuttg). 2016 Mar;66(3):136-40. doi: 10.1055/s-0035-1555784. Epub 2015 Jun 30.


Enhanced expression of sodium hydrogen exchanger (NHE)-1, 2 and 4 in the uteri of rat model for post-menopause under phytoestrogen genistein influence.

Chinigarzadeh A, Muniandy S, Salleh N.

Environ Toxicol Pharmacol. 2015 Jul;40(1):39-48. doi: 10.1016/j.etap.2015.05.003. Epub 2015 May 11.


Effects of a phyto complex on well-being of climacteric women.

Quattrocchi T, Micali E, Gentile A, La Ferrera EG, Barbaro L, Ciarcià S, Corrado F, Di Costa M, Fazio R, Licenziato R, Marcazzò A, Minniti R, Riccobene R, Russello CM, Cancellieri F.

J Obstet Gynaecol Res. 2015 Jul;41(7):1093-8. doi: 10.1111/jog.12659. Epub 2015 Feb 6.


Isoflavones in food supplements: chemical profile, label accordance and permeability study in Caco-2 cells.

Almeida IM, Rodrigues F, Sarmento B, Alves RC, Oliveira MB.

Food Funct. 2015 Mar;6(3):938-46. doi: 10.1039/c4fo01144a.


A cross-sectional study of equol producer status and self-reported vasomotor symptoms.

Newton KM, Reed SD, Uchiyama S, Qu C, Ueno T, Iwashita S, Gunderson G, Fuller S, Lampe JW.

Menopause. 2015 May;22(5):489-95. doi: 10.1097/GME.0000000000000363.


Isoflavone supplement composition and equol producer status affect gene expression in adipose tissue: a double-blind, randomized, placebo-controlled crossover trial in postmenopausal women.

van der Velpen V, Geelen A, Hollman PC, Schouten EG, van 't Veer P, Afman LA.

Am J Clin Nutr. 2014 Nov;100(5):1269-77. doi: 10.3945/ajcn.114.088484. Epub 2014 Aug 20.


Large inter-individual variation in isoflavone plasma concentration limits use of isoflavone intake data for risk assessment.

van der Velpen V, Hollman PC, van Nielen M, Schouten EG, Mensink M, Van't Veer P, Geelen A.

Eur J Clin Nutr. 2014 Oct;68(10):1141-7. doi: 10.1038/ejcn.2014.108. Epub 2014 Jun 18.


Soy foods, isoflavones, and the health of postmenopausal women.

Messina M.

Am J Clin Nutr. 2014 Jul;100 Suppl 1:423S-30S. doi: 10.3945/ajcn.113.071464. Epub 2014 Jun 4.


Breast cancer cell apoptosis with phytoestrogens is dependent on an estrogen-deprived state.

Obiorah IE, Fan P, Jordan VC.

Cancer Prev Res (Phila). 2014 Sep;7(9):939-49. doi: 10.1158/1940-6207.CAPR-14-0061. Epub 2014 Jun 3.


[Effect of genistein combined with anastrozole on mammary tumors in ovariectomized rats].

Wang L, Kang XM, Song Y, Ma WJ, Zhao H, Zhang QY.

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2014 Apr;34(4):486-9. Chinese.


Genistein attenuates brain damage induced by transient cerebral ischemia through up-regulation of ERK activity in ovariectomized mice.

Wang S, Wei H, Cai M, Lu Y, Hou W, Yang Q, Dong H, Xiong L.

Int J Biol Sci. 2014 Apr 8;10(4):457-65. doi: 10.7150/ijbs.7562. eCollection 2014.


S-(-)equol producing status not associated with breast cancer risk among low isoflavone-consuming US postmenopausal women undergoing a physician-recommended breast biopsy.

Virk-Baker MK, Barnes S, Krontiras H, Nagy TR.

Nutr Res. 2014 Feb;34(2):116-25. doi: 10.1016/j.nutres.2013.12.002. Epub 2013 Dec 18.

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