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Items: 1 to 20 of 183

1.

Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection.

Daniels BP, Jujjavarapu H, Durrant DM, Williams JL, Green RR, White JP, Lazear HM, Gale M Jr, Diamond MS, Klein RS.

J Clin Invest. 2017 Jan 30. pii: 88720. doi: 10.1172/JCI88720. [Epub ahead of print]

PMID:
28134626
2.

MLKL Activation Triggers NLRP3-Mediated Processing and Release of IL-1β Independently of Gasdermin-D.

Gutierrez KD, Davis MA, Daniels BP, Olsen TM, Ralli-Jain P, Tait SW, Gale M Jr, Oberst A.

J Immunol. 2017 Mar 1;198(5):2156-2164. doi: 10.4049/jimmunol.1601757.

PMID:
28130493
3.

MAVS is essential for primary CD4+ T cell immunity but not for recall T cell responses following an attenuated West Nile virus infection.

Luo H, Winkelmann E, Xie G, Fang R, Peng BH, Li L, Lazear HM, Paessler S, Diamond MS, Gale M Jr, Barrett AD, Wang T.

J Virol. 2017 Jan 11. pii: JVI.02097-16. doi: 10.1128/JVI.02097-16. [Epub ahead of print]

PMID:
28077630
4.

Correction: Hepatitis C Virus Sensing by Human Trophoblasts Induces Innate Immune Responses and Recruitment of Maternal NK Cells: Potential Implications for Limiting Vertical Transmission.

Giugliano S, Petroff MG, Warren BD, Jasti S, Linscheid C, Ward A, Kramer A, Dobrinskikh E, Sheiko MA, Gale M Jr, Golden-Mason L, Winn VD, Rosen HR.

J Immunol. 2017 Jan 15;198(2):972. doi: 10.4049/jimmunol.1601926. No abstract available.

PMID:
28069758
5.

RNA-Seq in the Collaborative Cross.

Green R, Wilkins C, Ferris MT, Gale M Jr.

Methods Mol Biol. 2017;1488:251-263.

PMID:
27933528
6.

Transcriptional profiles of WNV neurovirulence in a genetically diverse Collaborative Cross population.

Green R, Wilkins C, Thomas S, Sekine A, Ireton RC, Ferris MT, Hendrick DM, Voss K, Pardo-Manuel de Villena F, Baric RS, Heise MT, Gale M Jr.

Genom Data. 2016 Oct 14;10:137-140.

7.

Identifying protective host gene expression signatures within the spleen during West Nile virus infection in the collaborative cross model.

Green R, Wilkins C, Thomas S, Sekine A, Ireton RC, Ferris MT, Hendrick DM, Voss K, de Villena FP, Baric R, Heise M, Gale M Jr.

Genom Data. 2016 Oct 14;10:114-117.

8.

Hepatitis-C-virus-induced microRNAs dampen interferon-mediated antiviral signaling.

Jarret A, McFarland AP, Horner SM, Kell A, Schwerk J, Hong M, Badil S, Joslyn RC, Baker DP, Carrington M, Hagedorn CH, Gale M Jr, Savan R.

Nat Med. 2016 Dec;22(12):1475-1481. doi: 10.1038/nm.4211.

PMID:
27841874
9.

A Mouse Model of Chronic West Nile Virus Disease.

Graham JB, Swarts JL, Wilkins C, Thomas S, Green R, Sekine A, Voss KM, Ireton RC, Mooney M, Choonoo G, Miller DR, Treuting PM, Pardo Manuel de Villena F, Ferris MT, McWeeney S, Gale M Jr, Lund JM.

PLoS Pathog. 2016 Nov 2;12(11):e1005996. doi: 10.1371/journal.ppat.1005996.

10.

Interferon lambda 4 expression is suppressed by the host during viral infection.

Hong M, Schwerk J, Lim C, Kell A, Jarret A, Pangallo J, Loo YM, Liu S, Hagedorn CH, Gale M Jr, Savan R.

J Exp Med. 2016 Nov 14;213(12):2539-2552.

PMID:
27799623
11.

Fetal brain lesions after subcutaneous inoculation of Zika virus in a pregnant nonhuman primate.

Adams Waldorf KM, Stencel-Baerenwald JE, Kapur RP, Studholme C, Boldenow E, Vornhagen J, Baldessari A, Dighe MK, Thiel J, Merillat S, Armistead B, Tisoncik-Go J, Green RR, Davis MA, Dewey EC, Fairgrieve MR, Gatenby JC, Richards T, Garden GA, Diamond MS, Juul SE, Grant RF, Kuller L, Shaw DW, Ogle J, Gough GM, Lee W, English C, Hevner RF, Dobyns WB, Gale M Jr, Rajagopal L.

Nat Med. 2016 Nov;22(11):1256-1259. doi: 10.1038/nm.4193.

PMID:
27618651
12.

Regulation of Retinoic Acid Inducible Gene-I (RIG-I) Activation by the Histone Deacetylase 6.

Liu HM, Jiang F, Loo YM, Hsu S, Hsiang TY, Marcotrigiano J, Gale M Jr.

EBioMedicine. 2016 Jul;9:195-206. doi: 10.1016/j.ebiom.2016.06.015.

13.

MAVS Expressed by Hematopoietic Cells Is Critical for Control of West Nile Virus Infection and Pathogenesis.

Zhao J, Vijay R, Zhao J, Gale M Jr, Diamond MS, Perlman S.

J Virol. 2016 Jul 27;90(16):7098-108. doi: 10.1128/JVI.00707-16.

14.

S6K-STING interaction regulates cytosolic DNA-mediated activation of the transcription factor IRF3.

Wang F, Alain T, Szretter KJ, Stephenson K, Pol JG, Atherton MJ, Hoang HD, Fonseca BD, Zakaria C, Chen L, Rangwala Z, Hesch A, Chan ES, Tuinman C, Suthar MS, Jiang Z, Ashkar AA, Thomas G, Kozma SC, Gale M Jr, Fitzgerald KA, Diamond MS, Mossman K, Sonenberg N, Wan Y, Lichty BD.

Nat Immunol. 2016 May;17(5):514-22. doi: 10.1038/ni.3433.

PMID:
27043414
15.

Transcriptional analysis of antiviral small molecule therapeutics as agonists of the RLR pathway.

Green RR, Wilkins C, Pattabhi S, Dong R, Loo Y, Gale M Jr.

Genom Data. 2016 Feb 1;7:290-2. doi: 10.1016/j.gdata.2016.01.020.

16.

The Hepatitis C Virus-Induced Membranous Web and Associated Nuclear Transport Machinery Limit Access of Pattern Recognition Receptors to Viral Replication Sites.

Neufeldt CJ, Joyce MA, Van Buuren N, Levin A, Kirkegaard K, Gale M Jr, Tyrrell DL, Wozniak RW.

PLoS Pathog. 2016 Feb 10;12(2):e1005428. doi: 10.1371/journal.ppat.1005428.

17.

Membrane Perturbation-Associated Ca2+ Signaling and Incoming Genome Sensing Are Required for the Host Response to Low-Level Enveloped Virus Particle Entry.

Hare DN, Collins SE, Mukherjee S, Loo YM, Gale M Jr, Janssen LJ, Mossman KL.

J Virol. 2015 Dec 30;90(6):3018-27. doi: 10.1128/JVI.02642-15.

18.

SnapShot: Interferon Signaling.

Chow KT, Gale M Jr.

Cell. 2015 Dec 17;163(7):1808-1808.e1. doi: 10.1016/j.cell.2015.12.008.

19.

Targeting Innate Immunity for Antiviral Therapy through Small Molecule Agonists of the RLR Pathway.

Pattabhi S, Wilkins CR, Dong R, Knoll ML, Posakony J, Kaiser S, Mire CE, Wang ML, Ireton RC, Geisbert TW, Bedard KM, Iadonato SP, Loo YM, Gale M Jr.

J Virol. 2015 Dec 16;90(5):2372-87. doi: 10.1128/JVI.02202-15.

20.

Identification of a Natural Viral RNA Motif That Optimizes Sensing of Viral RNA by RIG-I.

Xu J, Mercado-López X, Grier JT, Kim WK, Chun LF, Irvine EB, Del Toro Duany Y, Kell A, Hur S, Gale M Jr, Raj A, López CB.

MBio. 2015 Oct 6;6(5):e01265-15. doi: 10.1128/mBio.01265-15.

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