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Items: 1 to 20 of 31


Weighted Burden Analysis of Exome-Sequenced Case-Control Sample Implicates Synaptic Genes in Schizophrenia Aetiology.

Curtis D, Coelewij L, Liu SH, Humphrey J, Mott R.

Behav Genet. 2018 May;48(3):198-208. doi: 10.1007/s10519-018-9893-3. Epub 2018 Mar 21.


The functions of Reelin in membrane trafficking and cytoskeletal dynamics: implications for neuronal migration, polarization and differentiation.

Santana J, Marzolo MP.

Biochem J. 2017 Sep 7;474(18):3137-3165. doi: 10.1042/BCJ20160628. Review.


Striatal-enriched Tyrosine Protein Phosphatase (STEP) in the Mechanisms of Depressive Disorders.

Kulikova E, Kulikov A.

Curr Protein Pept Sci. 2017 Aug 30;18(11):1152-1162. doi: 10.2174/1389203718666170710121532. Review.


Nicotine-induced neuroplasticity counteracts the effect of schizophrenia-linked neuregulin 1 signaling on NMDAR function in the rat hippocampus.

Yamazaki Y, Sumikawa K.

Neuropharmacology. 2017 Feb;113(Pt A):386-395. doi: 10.1016/j.neuropharm.2016.10.021. Epub 2016 Oct 23.


Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models.

Xu J, Hartley BJ, Kurup P, Phillips A, Topol A, Xu M, Ononenyi C, Foscue E, Ho SM, Baguley TD, Carty N, Barros CS, Müller U, Gupta S, Gochman P, Rapoport J, Ellman JA, Pittenger C, Aronow B, Nairn AC, Nestor MW, Lombroso PJ, Brennand KJ.

Mol Psychiatry. 2018 Feb;23(2):271-281. doi: 10.1038/mp.2016.163. Epub 2016 Oct 18.


Effects of sex and DTNBP1 (dysbindin) null gene mutation on the developmental GluN2B-GluN2A switch in the mouse cortex and hippocampus.

Sinclair D, Cesare J, McMullen M, Carlson GC, Hahn CG, Borgmann-Winter KE.

J Neurodev Disord. 2016 May 1;8:14. doi: 10.1186/s11689-016-9148-7. eCollection 2016.


5-HT6 Receptor Antagonists: Potential Efficacy for the Treatment of Cognitive Impairment in Schizophrenia.

de Bruin NM, Kruse CG.

Curr Pharm Des. 2015;21(26):3739-59. Review.


Glutathione deficit impairs myelin maturation: relevance for white matter integrity in schizophrenia patients.

Monin A, Baumann PS, Griffa A, Xin L, Mekle R, Fournier M, Butticaz C, Klaey M, Cabungcal JH, Steullet P, Ferrari C, Cuenod M, Gruetter R, Thiran JP, Hagmann P, Conus P, Do KQ.

Mol Psychiatry. 2015 Jul;20(7):827-38. doi: 10.1038/mp.2014.88. Epub 2014 Aug 26.


Downstream effects of striatal-enriched protein tyrosine phosphatase reduction on RNA expression in vivo and in vitro.

Reinhart VL, Nguyen T, Gerwien R Jr, Kuhn M, Yates PD, Lanz TA.

Neuroscience. 2014 Oct 10;278:62-9. doi: 10.1016/j.neuroscience.2014.08.002. Epub 2014 Aug 15.


Behavioral characterization of striatal-enriched protein tyrosine phosphatase (STEP) knockout mice.

Sukoff Rizzo SJ, Lotarski SM, Stolyar P, McNally T, Arturi C, Roos M, Finley JE, Reinhart V, Lanz TA.

Genes Brain Behav. 2014 Sep;13(7):643-52. doi: 10.1111/gbb.12169. Epub 2014 Aug 28.


Axon-glia interaction and membrane traffic in myelin formation.

White R, Krämer-Albers EM.

Front Cell Neurosci. 2014 Jan 6;7:284. doi: 10.3389/fncel.2013.00284. eCollection 2014 Jan 6. Review.


Association study of the Fyn gene with schizophrenia in the Chinese-Han population.

Wu L, Huang Y, Li J, Zhao H, Du H, Jin Q, Zhao X, Ma H, Zhu G.

Psychiatr Genet. 2013 Feb;23(1):39-40. doi: 10.1097/YPG.0b013e328358640b. No abstract available.


A common STEP in the synaptic pathology of diverse neuropsychiatric disorders.

Johnson MA, Lombroso PJ.

Yale J Biol Med. 2012 Dec;85(4):481-90. Epub 2012 Dec 13. Review.


Therapeutic implications for striatal-enriched protein tyrosine phosphatase (STEP) in neuropsychiatric disorders.

Goebel-Goody SM, Baum M, Paspalas CD, Fernandez SM, Carty NC, Kurup P, Lombroso PJ.

Pharmacol Rev. 2012 Jan;64(1):65-87. doi: 10.1124/pr.110.003053. Epub 2011 Nov 16. Review.


Abnormal activity of the MAPK- and cAMP-associated signaling pathways in frontal cortical areas in postmortem brain in schizophrenia.

Funk AJ, McCullumsmith RE, Haroutunian V, Meador-Woodruff JH.

Neuropsychopharmacology. 2012 Mar;37(4):896-905. doi: 10.1038/npp.2011.267. Epub 2011 Nov 2.


Control of interneuron dendritic growth through NRG1/erbB4-mediated kalirin-7 disinhibition.

Cahill ME, Jones KA, Rafalovich I, Xie Z, Barros CS, Müller U, Penzes P.

Mol Psychiatry. 2012 Jan;17(1):1, 99-107. doi: 10.1038/mp.2011.35. Epub 2011 Apr 12.


Dopamine D1 receptor-mediated NMDA receptor insertion depends on Fyn but not Src kinase pathway in prefrontal cortical neurons.

Hu JL, Liu G, Li YC, Gao WJ, Huang YQ.

Mol Brain. 2010 Jun 22;3:20. doi: 10.1186/1756-6606-3-20.


Positive and negative symptoms in schizophrenia: the NMDA receptor hypofunction hypothesis, neuregulin/ErbB4 and synapse regression.

Bennett M.

Aust N Z J Psychiatry. 2009 Aug;43(8):711-21. doi: 10.1080/00048670903001943. Review.


Decreased expression of Fyn protein and disbalanced alternative splicing patterns in platelets from patients with schizophrenia.

Hattori K, Fukuzako H, Hashiguchi T, Hamada S, Murata Y, Isosaka T, Yuasa S, Yagi T.

Psychiatry Res. 2009 Jul 30;168(2):119-28. doi: 10.1016/j.psychres.2008.04.014. Epub 2009 Jun 6.


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