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Items: 7


Are FXR Family Proteins Integrators of Dopamine Signaling and Glutamatergic Neurotransmission in Mental Illnesses?

Khlghatyan J, Beaulieu JM.

Front Synaptic Neurosci. 2018 Jul 24;10:22. doi: 10.3389/fnsyn.2018.00022. eCollection 2018. Review.


Mental Illnesses-Associated Fxr1 and Its Negative Regulator Gsk3β Are Modulators of Anxiety and Glutamatergic Neurotransmission.

Khlghatyan J, Evstratova A, Chamberland S, Marakhovskaia A, Bahremand A, Toth K, Beaulieu JM.

Front Mol Neurosci. 2018 Apr 12;11:119. doi: 10.3389/fnmol.2018.00119. eCollection 2018.


The interaction of GSK3B and FXR1 genotypes may influence the mania and depression dimensions in mood disorders.

Bureau A, Beaulieu JM, Paccalet T, Chagnon YC, Maziade M.

J Affect Disord. 2017 Apr 15;213:172-177. doi: 10.1016/j.jad.2017.02.023. Epub 2017 Feb 16.


Genome-wide identification of splicing QTLs in the human brain and their enrichment among schizophrenia-associated loci.

Takata A, Matsumoto N, Kato T.

Nat Commun. 2017 Feb 27;8:14519. doi: 10.1038/ncomms14519.


Analyzing the Role of MicroRNAs in Schizophrenia in the Context of Common Genetic Risk Variants.

Hauberg ME, Roussos P, Grove J, Børglum AD, Mattheisen M; Schizophrenia Working Group of the Psychiatric Genomics Consortium.

JAMA Psychiatry. 2016 Apr;73(4):369-77. doi: 10.1001/jamapsychiatry.2015.3018.


Accumulated common variants in the broader fragile X gene family modulate autistic phenotypes.

Stepniak B, Kästner A, Poggi G, Mitjans M, Begemann M, Hartmann A, Van der Auwera S, Sananbenesi F, Krueger-Burg D, Matuszko G, Brosi C, Homuth G, Völzke H, Benseler F, Bagni C, Fischer U, Dityatev A, Grabe HJ, Rujescu D, Fischer A, Ehrenreich H.

EMBO Mol Med. 2015 Dec;7(12):1565-79. doi: 10.15252/emmm.201505696.


FXR1P is a GSK3β substrate regulating mood and emotion processing.

Del'Guidice T, Latapy C, Rampino A, Khlghatyan J, Lemasson M, Gelao B, Quarto T, Rizzo G, Barbeau A, Lamarre C, Bertolino A, Blasi G, Beaulieu JM.

Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):E4610-9. doi: 10.1073/pnas.1506491112. Epub 2015 Aug 3.

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