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Evaluation of the Immunomodulatory Effects of Fucoidan Derived from Cladosiphon Okamuranus Tokida in Mice.

Tomori M, Nagamine T, Miyamoto T, Iha M.

Mar Drugs. 2019 Sep 24;17(10). pii: E547. doi: 10.3390/md17100547.


Selective Suppression of Cell Growth and Programmed Cell Death-Ligand 1 Expression in HT1080 Fibrosarcoma Cells by Low Molecular Weight Fucoidan Extract.

Teruya K, Kusumoto Y, Eto H, Nakamichi N, Shirahata S.

Mar Drugs. 2019 Jul 19;17(7). pii: E421. doi: 10.3390/md17070421.


The cooperative induction of macrophage activation by fucoidan derived from Cladosiphon okamuranus and β-glucan derived from Saccharomyces cerevisiae.

Miyazaki Y, Iwaihara Y, Bak J, Nakano H, Takeuchi S, Takeuchi H, Matsui T, Tachikawa D.

Biochem Biophys Res Commun. 2019 Aug 13;516(1):245-250. doi: 10.1016/j.bbrc.2019.06.010. Epub 2019 Jun 18.


Class A scavenger receptor expression and function in eight novel tadpole cell lines from the green frog (Lithobates clamitans) and the wood frog (Lithobates sylvatica).

Vo NTK, Everson J, Moore L, DeWitte-Orr SJ.

Cytotechnology. 2019 Jun 6:757-768. doi: 10.1007/s10616-019-00318-1. [Epub ahead of print]


Clinical applications of fucoidan in translational medicine for adjuvant cancer therapy.

Hsu HY, Hwang PA.

Clin Transl Med. 2019 May 1;8(1):15. doi: 10.1186/s40169-019-0234-9. Review.


Ascophyllan Induces Activation of Natural Killer Cells in Mice In Vivo and In Vitro.

Zhang W, Okimura T, Oda T, Jin JO.

Mar Drugs. 2019 Mar 28;17(4). pii: E197. doi: 10.3390/md17040197.


Effect of supplementation with n-3 polyunsaturated fatty acids and/or β-glucans on performance, feeding behaviour and immune status of Holstein Friesian bull calves during the pre- and post-weaning periods.

McDonnell RP, O' Doherty JV, Earley B, Clarke AM, Kenny DA.

J Anim Sci Biotechnol. 2019 Jan 29;10:7. doi: 10.1186/s40104-019-0317-x. eCollection 2019.


Pathway Analysis of Fucoidan Activity Using a Yeast Gene Deletion Library Screen.

Corban M, Ambrose M, Pagnon J, Stringer D, Karpiniec S, Park A, Eri R, Fitton JH, Gueven N.

Mar Drugs. 2019 Jan 14;17(1). pii: E54. doi: 10.3390/md17010054.


Application of marine-derived polysaccharides as immunostimulants in aquaculture: A review of current knowledge and further perspectives.

Mohan K, Ravichandran S, Muralisankar T, Uthayakumar V, Chandirasekar R, Seedevi P, Abirami RG, Rajan DK.

Fish Shellfish Immunol. 2019 Mar;86:1177-1193. doi: 10.1016/j.fsi.2018.12.072. Epub 2018 Dec 30. Review.


Downregulation of Microparticle Release and Pro-Inflammatory Properties of Activated Human Polymorphonuclear Neutrophils by LMW Fucoidan.

Moraes JA, Frony AC, Barcellos-de-Souza P, Menezes da Cunha M, Brasil Barbosa Calcia T, Benjamim CF, Boisson-Vidal C, Barja-Fidalgo C.

J Innate Immun. 2019;11(4):330-346. doi: 10.1159/000494220. Epub 2018 Dec 17.


Targeting macrophage scavenger receptor 1 promotes insulin resistance in obese male mice.

Cavallari JF, Anhê FF, Foley KP, Denou E, Chan RW, Bowdish DME, Schertzer JD.

Physiol Rep. 2018 Nov;6(22):e13930. doi: 10.14814/phy2.13930.


The effect of dietary fucoidan on growth, immune functions, blood characteristics and oxidative stress resistance of juvenile red sea bream, Pagrus major.

Sony NM, Ishikawa M, Hossain MS, Koshio S, Yokoyama S.

Fish Physiol Biochem. 2019 Feb;45(1):439-454. doi: 10.1007/s10695-018-0575-0. Epub 2018 Oct 5.


Endo-fucoidan hydrolases from glycoside hydrolase family 107 (GH107) display structural and mechanistic similarities to α-l-fucosidases from GH29.

Vickers C, Liu F, Abe K, Salama-Alber O, Jenkins M, Springate CMK, Burke JE, Withers SG, Boraston AB.

J Biol Chem. 2018 Nov 23;293(47):18296-18308. doi: 10.1074/jbc.RA118.005134. Epub 2018 Oct 3.


Immune Activation of RAW264.7 Macrophages by Low Molecular Weight Fucoidan Extracted from New Zealand Undaria pinnatifida.

Bi D, Yu B, Han Q, Lu J, White WL, Lai Q, Cai N, Luo W, Gu L, Li S, Xu H, Hu Z, Nie S, Xu X.

J Agric Food Chem. 2018 Oct 17;66(41):10721-10728. doi: 10.1021/acs.jafc.8b03698. Epub 2018 Oct 8.


Improved chemotherapy against breast cancer through immunotherapeutic activity of fucoidan decorated electrostatically assembled nanoparticles bearing doxorubicin.

Pawar VK, Singh Y, Sharma K, Shrivastav A, Sharma A, Singh A, Meher JG, Singh P, Raval K, Kumar A, Bora HK, Datta D, Lal J, Chourasia MK.

Int J Biol Macromol. 2019 Feb 1;122:1100-1114. doi: 10.1016/j.ijbiomac.2018.09.059. Epub 2018 Sep 13.


Combination of fucoidan-based magnetic nanoparticles and immunomodulators enhances tumour-localized immunotherapy.

Chiang CS, Lin YJ, Lee R, Lai YH, Cheng HW, Hsieh CH, Shyu WC, Chen SY.

Nat Nanotechnol. 2018 Aug;13(8):746-754. doi: 10.1038/s41565-018-0146-7. Epub 2018 May 14.


Structural characterization of a polysaccharide from Sargassum henslowianum, and its immunomodulatory effect on gastric cancer rat.

Han M, Sun P, Li Y, Wu G, Nie J.

Int J Biol Macromol. 2018 Mar;108:1120-1127. doi: 10.1016/j.ijbiomac.2017.12.109. Epub 2017 Dec 21.


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