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Enzyme-Aided Extraction of Fucoidan by AMG Augments the Functionality of EPCs through Regulation of the AKT/Rheb Signaling Pathway.

Rethineswaran VK, Kim YJ, Jang WB, Ji ST, Kang S, Kim DY, Park JH, Van LTH, Giang LTT, Ha JS, Yun J, Lee DH, Yu SN, Park SG, Ahn SC, Kwon SM.

Mar Drugs. 2019 Jul 3;17(7). pii: E392. doi: 10.3390/md17070392.


Fucoidan Inhibits the Proliferation of Leiomyoma Cells and Decreases Extracellular Matrix-Associated Protein Expression.

Chen HY, Huang TC, Lin LC, Shieh TM, Wu CH, Wang KL, Hong YH, Hsia SM.

Cell Physiol Biochem. 2018;49(5):1970-1986. doi: 10.1159/000493660. Epub 2018 Sep 20.


Influence of Modified Fucoidan and Related Sulfated Oligosaccharides on Hematopoiesis in Cyclophosphamide-Induced Mice.

Anisimova NY, Ustyuzhanina NE, Bilan MI, Donenko FV, Ushakova NA, Usov AI, Kiselevskiy MV, Nifantiev NE.

Mar Drugs. 2018 Sep 13;16(9). pii: E333. doi: 10.3390/md16090333.


Long-Term Priming by Three Small Molecules Is a Promising Strategy for Enhancing Late Endothelial Progenitor Cell Bioactivities.

Kim YJ, Ji ST, Kim DY, Jung SY, Kang S, Park JH, Jang WB, Yun J, Ha J, Lee DH, Kwon SM.

Mol Cells. 2018 Jun;41(6):582-590. doi: 10.14348/molcells.2018.0011. Epub 2018 Jun 12.


Fucoidan/VEGF-based surface modification of decellularized pulmonary heart valve improves the antithrombotic and re-endothelialization potential of bioprostheses.

Marinval N, Morenc M, Labour MN, Samotus A, Mzyk A, Ollivier V, Maire M, Jesse K, Bassand K, Niemiec-Cyganek A, Haddad O, Jacob MP, Chaubet F, Charnaux N, Wilczek P, Hlawaty H.

Biomaterials. 2018 Jul;172:14-29. doi: 10.1016/j.biomaterials.2018.01.054. Epub 2018 Mar 16.


Fucoidan Rescues p-Cresol-Induced Cellular Senescence in Mesenchymal Stem Cells via FAK-Akt-TWIST Axis.

Lee JH, Yun CW, Hur J, Lee SH.

Mar Drugs. 2018 Apr 6;16(4). pii: E121. doi: 10.3390/md16040121.


Large and Small Assembly: Combining Functional Macromolecules with Small Peptides to Control the Morphology of Skeletal Muscle Progenitor Cells.

Li R, McRae NL, McCulloch DR, Boyd-Moss M, Barrow CJ, Nisbet DR, Stupka N, Williams RJ.

Biomacromolecules. 2018 Mar 12;19(3):825-837. doi: 10.1021/acs.biomac.7b01632. Epub 2018 Feb 13.


Enhanced Differentiation of Human Preosteoblasts on Electrospun Blend Fiber Mats of Polydioxanone and Anionic Sulfated Polysaccharides.

Goonoo N, Bhaw-Luximon A, Jonas U, Jhurry D, Schönherr H.

ACS Biomater Sci Eng. 2017 Dec 11;3(12):3447-3458. doi: 10.1021/acsbiomaterials.7b00350. Epub 2017 Oct 12.


Fucoidan-induced osteogenic differentiation promotes angiogenesis by inducing vascular endothelial growth factor secretion and accelerates bone repair.

Kim BS, Yang SS, You HK, Shin HI, Lee J.

J Tissue Eng Regen Med. 2018 Mar;12(3):e1311-e1324. doi: 10.1002/term.2509. Epub 2017 Oct 4.


Crude Fucoidan Extracts Impair Angiogenesis in Models Relevant for Bone Regeneration and Osteosarcoma via Reduction of VEGF and SDF-1.

Wang F, Schmidt H, Pavleska D, Wermann T, Seekamp A, Fuchs S.

Mar Drugs. 2017 Jun 20;15(6). pii: E186. doi: 10.3390/md15060186.


Prospective Review of Mesenchymal Stem Cells Differentiation into Osteoblasts.

Garg P, Mazur MM, Buck AC, Wandtke ME, Liu J, Ebraheim NA.

Orthop Surg. 2017 Feb;9(1):13-19. doi: 10.1111/os.12304. Epub 2017 Mar 9. Review.


Silencing Prion Protein in HT29 Human Colorectal Cancer Cells Enhances Anticancer Response to Fucoidan.

Yun CW, Yun S, Lee JH, Han YS, Yoon YM, An D, Lee SH.

Anticancer Res. 2016 Sep;36(9):4449-58.


The comparison of structure and anticancer activity in vitro of polysaccharides from brown algae Alaria marginata and A. angusta.

Usoltseva Menshova RV, Anastyuk SD, Shevchenko NM, Zvyagintseva TN, Ermakova SP.

Carbohydr Polym. 2016 Nov 20;153:258-265. doi: 10.1016/j.carbpol.2016.07.103. Epub 2016 Jul 26.


Interaction of stem cells with nano hydroxyapatite-fucoidan bionanocomposites for bone tissue regeneration.

Tae Young A, Kang JH, Kang DJ, Venkatesan J, Chang HK, Bhatnagar I, Chang KY, Hwang JH, Salameh Z, Kim SK, Kim HT, Kim DG.

Int J Biol Macromol. 2016 Dec;93(Pt B):1488-1491. doi: 10.1016/j.ijbiomac.2016.07.027. Epub 2016 Jul 9.


Fucoidan improves bioactivity and vasculogenic potential of mesenchymal stem cells in murine hind limb ischemia associated with chronic kidney disease.

Lee JH, Ryu JM, Han YS, Zia MF, Kwon HY, Noh H, Han HJ, Lee SH.

J Mol Cell Cardiol. 2016 Aug;97:169-79. doi: 10.1016/j.yjmcc.2016.05.011. Epub 2016 May 20.


Three dimensional alginate-fucoidan composite hydrogel augments the chondrogenic differentiation of mesenchymal stromal cells.

Karunanithi P, Murali MR, Samuel S, Raghavendran HRB, Abbas AA, Kamarul T.

Carbohydr Polym. 2016 Aug 20;147:294-303. doi: 10.1016/j.carbpol.2016.03.102. Epub 2016 Apr 2.


Incorporation of Fucoidan in β-Tricalcium phosphate-Chitosan scaffold prompts the differentiation of human bone marrow stromal cells into osteogenic lineage.

Puvaneswary S, Raghavendran HB, Talebian S, Murali MR, A Mahmod S, Singh S, Kamarul T.

Sci Rep. 2016 Apr 12;6:24202. doi: 10.1038/srep24202.


Preparation and characterization of chitosan-natural nano hydroxyapatite-fucoidan nanocomposites for bone tissue engineering.

Lowe B, Venkatesan J, Anil S, Shim MS, Kim SK.

Int J Biol Macromol. 2016 Dec;93(Pt B):1479-1487. doi: 10.1016/j.ijbiomac.2016.02.054. Epub 2016 Feb 26.


Fabrication and in vitro biological activity of βTCP-Chitosan-Fucoidan composite for bone tissue engineering.

Puvaneswary S, Talebian S, Raghavendran HB, Murali MR, Mehrali M, Afifi AM, Kasim NH, Kamarul T.

Carbohydr Polym. 2015 Dec 10;134:799-807. doi: 10.1016/j.carbpol.2015.07.098. Epub 2015 Aug 1.


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