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Items: 1 to 20 of 288

1.

APD-Containing Cyclolipodepsipeptides Target Mitochondrial Function in Hypoxic Cancer Cells.

Jacobsen KM, Villadsen NL, Tørring T, Nielsen CB, Salomón T, Nielsen MM, Tsakos M, Sibbersen C, Scavenius C, Nielsen R, Christensen EI, Guerra PF, Bross P, Pedersen JS, Enghild JJ, Johannsen M, Frøkiær J, Overgaard J, Horsman MR, Busk M, Poulsen TB.

Cell Chem Biol. 2018 Aug 9. pii: S2451-9456(18)30262-9. doi: 10.1016/j.chembiol.2018.07.010. [Epub ahead of print]

PMID:
30122371
2.

Small-Molecule Probes for Affinity-Guided Introduction of Biocom-patible Handles on Metal-Binding Proteins.

Mortensen MR, Skovsgaard M, Okholm AH, Scavenius C, Dupont DM, Rosen CB, Enghild JJ, Kjems J, Gothelf KV.

Bioconjug Chem. 2018 Aug 9. doi: 10.1021/acs.bioconjchem.8b00424. [Epub ahead of print]

PMID:
30091905
3.

α-Synucleins from Animal Species Show Low Fibrillation Propensities and Weak Oligomer Membrane Disruption.

Sahin C, Kjær L, Christensen MS, N Pedersen J, Christiansen G, Pérez AW, Møller IM, Enghild JJ, Pedersen JS, Larsen K, Otzen DE.

Biochemistry. 2018 Aug 15. doi: 10.1021/acs.biochem.8b00627. [Epub ahead of print]

PMID:
30067901
4.

A Novel Biological Role for Peptidyl-Arginine Deiminases: Citrullination of Cathelicidin LL-37 Controls the Immunostimulatory Potential of Cell-Free DNA.

Wong A, Bryzek D, Dobosz E, Scavenius C, Svoboda P, Rapala-Kozik M, Lesner A, Frydrych I, Enghild J, Mydel P, Pohl J, Thompson PR, Potempa J, Koziel J.

J Immunol. 2018 Apr 1;200(7):2327-2340. doi: 10.4049/jimmunol.1701391. Epub 2018 Feb 23.

PMID:
29475987
5.

Frequently used bioinformatics tools overestimate the damaging effect of allelic variants.

Andersen LL, Terczyńska-Dyla E, Mørk N, Scavenius C, Enghild JJ, Höning K, Hornung V, Christiansen M, Mogensen TH, Hartmann R.

Genes Immun. 2017 Dec 4. doi: 10.1038/s41435-017-0002-z. [Epub ahead of print]

PMID:
29217828
6.

Mutation-Induced Deamidation of Corneal Dystrophy-Related Transforming Growth Factor β-Induced Protein.

Nielsen NS, Juhl DW, Poulsen ET, Lukassen MV, Poulsen EC, Risør MW, Scavenius C, Enghild JJ.

Biochemistry. 2017 Dec 12;56(49):6470-6480. doi: 10.1021/acs.biochem.7b00668. Epub 2017 Nov 22.

PMID:
29140698
7.

Proteomic profiling of TGFBI-null mouse corneas reveals only minor changes in matrix composition supportive of TGFBI knockdown as therapy against TGFBI-linked corneal dystrophies.

Poulsen ET, Runager K, Nielsen NS, Lukassen MV, Thomsen K, Snider P, Simmons O, Vorum H, Conway SJ, Enghild JJ.

FEBS J. 2018 Jan;285(1):101-114. doi: 10.1111/febs.14321. Epub 2017 Nov 23.

PMID:
29117645
8.

Structural and Functional Implications of Human Transforming Growth Factor β-Induced Protein, TGFBIp, in Corneal Dystrophies.

García-Castellanos R, Nielsen NS, Runager K, Thøgersen IB, Lukassen MV, Poulsen ET, Goulas T, Enghild JJ, Gomis-Rüth FX.

Structure. 2017 Nov 7;25(11):1740-1750.e2. doi: 10.1016/j.str.2017.09.001. Epub 2017 Oct 5.

PMID:
28988748
9.

How glycosaminoglycans promote fibrillation of salmon calcitonin.

Malmos KG, Bjerring M, Jessen CM, Nielsen EHT, Poulsen ET, Christiansen G, Vosegaard T, Skrydstrup T, Enghild JJ, Pedersen JS, Otzen DE.

J Biol Chem. 2017 Sep 22;292(38):15992. doi: 10.1074/jbc.A116.715466. No abstract available.

10.

Transcriptome analysis of the response of Burmese python to digestion.

Duan J, Sanggaard KW, Schauser L, Lauridsen SE, Enghild JJ, Schierup MH, Wang T.

Gigascience. 2017 Aug 1;6(8):1-18. doi: 10.1093/gigascience/gix057.

11.

Characterisation of protein families in spider digestive fluids and their role in extra-oral digestion.

Walter A, Bechsgaard J, Scavenius C, Dyrlund TS, Sanggaard KW, Enghild JJ, Bilde T.

BMC Genomics. 2017 Aug 10;18(1):600. doi: 10.1186/s12864-017-3987-9.

12.

Analysis of Factor D Isoforms in Malpuech-Michels-Mingarelli-Carnevale Patients Highlights the Role of MASP-3 as a Maturase in the Alternative Pathway of Complement.

Pihl R, Jensen L, Hansen AG, Thøgersen IB, Andres S, Dagnæs-Hansen F, Oexle K, Enghild JJ, Thiel S.

J Immunol. 2017 Aug 9. pii: ji1700518. doi: 10.4049/jimmunol.1700518. [Epub ahead of print]

PMID:
28794230
13.

Critical Influence of Cosolutes and Surfaces on the Assembly of Serpin-Derived Amyloid Fibrils.

Risør MW, Juhl DW, Bjerring M, Mathiesen J, Enghild JJ, Nielsen NC, Otzen DE.

Biophys J. 2017 Aug 8;113(3):580-596. doi: 10.1016/j.bpj.2017.06.030.

14.

Activation of Complement by Pigment Epithelium-Derived Factor in Rheumatoid Arthritis.

Vogt LM, Talens S, Kwasniewicz E, Scavenius C, Struglics A, Enghild JJ, Saxne T, Blom AM.

J Immunol. 2017 Aug 1;199(3):1113-1121. doi: 10.4049/jimmunol.1700018. Epub 2017 Jun 21.

15.

An Aberrant Phosphorylation of Amyloid Precursor Protein Tyrosine Regulates Its Trafficking and the Binding to the Clathrin Endocytic Complex in Neural Stem Cells of Alzheimer's Disease Patients.

Poulsen ET, Iannuzzi F, Rasmussen HF, Maier TJ, Enghild JJ, Jørgensen AL, Matrone C.

Front Mol Neurosci. 2017 Mar 15;10:59. doi: 10.3389/fnmol.2017.00059. eCollection 2017.

16.

Serum Amyloid P Component (SAP) Interactome in Human Plasma Containing Physiological Calcium Levels.

Poulsen ET, Pedersen KW, Marzeda AM, Enghild JJ.

Biochemistry. 2017 Feb 14;56(6):896-902. doi: 10.1021/acs.biochem.6b01027. Epub 2017 Feb 1.

PMID:
28098450
17.

Mirolysin, a LysargiNase from Tannerella forsythia, proteolytically inactivates the human cathelicidin, LL-37.

Koneru L, Ksiazek M, Waligorska I, Straczek A, Lukasik M, Madej M, Thøgersen IB, Enghild JJ, Potempa J.

Biol Chem. 2016 Dec 20. pii: /j/bchm.ahead-of-print/hsz-2016-0267/hsz-2016-0267.xml. doi: 10.1515/hsz-2016-0267. [Epub ahead of print]

18.

Reactive Center Loop Insertion in α-1-Antitrypsin Captured by Accelerated Molecular Dynamics Simulation.

Andersen OJ, Risør MW, Poulsen EC, Nielsen NC, Miao Y, Enghild JJ, Schiøtt B.

Biochemistry. 2017 Jan 31;56(4):634-646. doi: 10.1021/acs.biochem.6b00839. Epub 2017 Jan 17.

PMID:
27995800
19.

Human Lysozyme Peptidase Resistance Is Perturbed by the Anionic Glycolipid Biosurfactant Rhamnolipid Produced by the Opportunistic Pathogen Pseudomonas aeruginosa.

Andersen KK, Vad BS, Scavenius C, Enghild JJ, Otzen DE.

Biochemistry. 2017 Jan 10;56(1):260-270. doi: 10.1021/acs.biochem.6b01009. Epub 2016 Dec 20.

PMID:
27931094
20.

Structural and functional probing of PorZ, an essential bacterial surface component of the type-IX secretion system of human oral-microbiomic Porphyromonas gingivalis.

Lasica AM, Goulas T, Mizgalska D, Zhou X, de Diego I, Ksiazek M, Madej M, Guo Y, Guevara T, Nowak M, Potempa B, Goel A, Sztukowska M, Prabhakar AT, Bzowska M, Widziolek M, Thøgersen IB, Enghild JJ, Simonian M, Kulczyk AW, Nguyen KA, Potempa J, Gomis-Rüth FX.

Sci Rep. 2016 Nov 24;6:37708. doi: 10.1038/srep37708.

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