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Items: 1 to 20 of 167

1.

Multiplex single-cell visualization of nucleic acids and protein during HIV infection.

Puray-Chavez M, Tedbury PR, Huber AD, Ukah OB, Yapo V, Liu D, Ji J, Wolf JJ, Engelman AN, Sarafianos SG.

Nat Commun. 2017 Dec 1;8(1):1882. doi: 10.1038/s41467-017-01693-z.

2.

LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis.

El Ashkar S, Schwaller J, Pieters T, Goossens S, Demeulemeester J, Christ F, Van Belle S, Juge S, Boeckx N, Engelman A, Van Vlierberghe P, Debyser Z, De Rijck J.

Blood. 2017 Oct 30. pii: blood-2017-05-786962. doi: 10.1182/blood-2017-05-786962. [Epub ahead of print]

PMID:
29084774
3.

Epidemiology, diagnosis, and optimal management of glioma in adolescents and young adults.

Diwanji TP, Engelman A, Snider JW, Mohindra P.

Adolesc Health Med Ther. 2017 Sep 22;8:99-113. doi: 10.2147/AHMT.S53391. eCollection 2017. Review.

4.

Resistance to pyridine-based inhibitor KF116 reveals an unexpected role of integrase in HIV-1 Gag-Pol polyprotein proteolytic processing.

Hoyte AC, Jamin AV, Koneru PC, Kobe MJ, Larue RC, Fuchs JR, Engelman AN, Kvaratskhelia M.

J Biol Chem. 2017 Dec 1;292(48):19814-19825. doi: 10.1074/jbc.M117.816645. Epub 2017 Sep 28.

PMID:
28972144
5.

CryoEM structure of MxB reveals a novel oligomerization interface critical for HIV restriction.

Alvarez FJD, He S, Perilla JR, Jang S, Schulten K, Engelman AN, Scheres SHW, Zhang P.

Sci Adv. 2017 Sep 15;3(9):e1701264. doi: 10.1126/sciadv.1701264. eCollection 2017 Sep.

6.

Risk perception and perceived self-efficacy of deaf and hard-of-hearing seniors and young adults in emergencies.

Engelman A, Ivey SL, Tseng W, Neuhauser L.

Am J Disaster Med. 2017 Winter;12(1):43-60. doi: 10.5055/ajdm.2017.0257.

PMID:
28822214
7.

Capsid-Dependent Host Factors in HIV-1 Infection.

Yamashita M, Engelman AN.

Trends Microbiol. 2017 Sep;25(9):741-755. doi: 10.1016/j.tim.2017.04.004. Epub 2017 May 18. Review.

PMID:
28528781
8.

Haematopoietic stem and progenitor cells from human pluripotent stem cells.

Sugimura R, Jha DK, Han A, Soria-Valles C, da Rocha EL, Lu YF, Goettel JA, Serrao E, Rowe RG, Malleshaiah M, Wong I, Sousa P, Zhu TN, Ditadi A, Keller G, Engelman AN, Snapper SB, Doulatov S, Daley GQ.

Nature. 2017 May 25;545(7655):432-438. doi: 10.1038/nature22370. Epub 2017 May 17.

PMID:
28514439
9.

Structural basis for spumavirus GAG tethering to chromatin.

Lesbats P, Serrao E, Maskell DP, Pye VE, O'Reilly N, Lindemann D, Engelman AN, Cherepanov P.

Proc Natl Acad Sci U S A. 2017 May 23;114(21):5509-5514. doi: 10.1073/pnas.1621159114. Epub 2017 May 10.

10.

Retroviral intasomes arising.

Engelman AN, Cherepanov P.

Curr Opin Struct Biol. 2017 Dec;47:23-29. doi: 10.1016/j.sbi.2017.04.005. Epub 2017 Apr 28. Review.

PMID:
28458055
11.

Risk perception and perceived self-efficacy of deaf and hard-of-hearing seniors and young adults in emergencies.

Engelman A, Ivey SL, Tseng W, Neuhauser L.

J Emerg Manag. 2017 Jan/Feb;15(1):7-15. doi: 10.5055/jem.2017.0309.

PMID:
28345748
12.

Retroviral integrase protein and intasome nucleoprotein complex structures.

Grawenhoff J, Engelman AN.

World J Biol Chem. 2017 Feb 26;8(1):32-44. doi: 10.4331/wjbc.v8.i1.32. Review.

13.

Inhibition of HIV-1 Maturation via Small-Molecule Targeting of the Amino-Terminal Domain in the Viral Capsid Protein.

Wang W, Zhou J, Halambage UD, Jurado KA, Jamin AV, Wang Y, Engelman AN, Aiken C.

J Virol. 2017 Apr 13;91(9). pii: e02155-16. doi: 10.1128/JVI.02155-16. Print 2017 May 1.

14.

A supramolecular assembly mediates lentiviral DNA integration.

Ballandras-Colas A, Maskell DP, Serrao E, Locke J, Swuec P, Jónsson SR, Kotecha A, Cook NJ, Pye VE, Taylor IA, Andrésdóttir V, Engelman AN, Costa A, Cherepanov P.

Science. 2017 Jan 6;355(6320):93-95. doi: 10.1126/science.aah7002.

15.

Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity.

Lu YF, Cahan P, Ross S, Sahalie J, Sousa PM, Hadland BK, Cai W, Serrao E, Engelman AN, Bernstein ID, Daley GQ.

Cell Rep. 2016 Dec 20;17(12):3178-3192. doi: 10.1016/j.celrep.2016.11.077.

16.

Estimating Survival in Patients With Lung Cancer and Brain Metastases: An Update of the Graded Prognostic Assessment for Lung Cancer Using Molecular Markers (Lung-molGPA).

Sperduto PW, Yang TJ, Beal K, Pan H, Brown PD, Bangdiwala A, Shanley R, Yeh N, Gaspar LE, Braunstein S, Sneed P, Boyle J, Kirkpatrick JP, Mak KS, Shih HA, Engelman A, Roberge D, Arvold ND, Alexander B, Awad MM, Contessa J, Chiang V, Hardie J, Ma D, Lou E, Sperduto W, Mehta MP.

JAMA Oncol. 2017 Jun 1;3(6):827-831. doi: 10.1001/jamaoncol.2016.3834.

PMID:
27892978
17.

Allosteric HIV-1 integrase inhibitors promote aberrant protein multimerization by directly mediating inter-subunit interactions: Structural and thermodynamic modeling studies.

Deng N, Hoyte A, Mansour YE, Mohamed MS, Fuchs JR, Engelman AN, Kvaratskhelia M, Levy R.

Protein Sci. 2016 Nov;25(11):1911-1917. doi: 10.1002/pro.2997. Epub 2016 Aug 17.

18.

Correction: Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration.

Zurnic I, Hütter S, Rzeha U, Helbig R, Stanke N, Reh J, Müllers E, Hamann MV, Kern T, Gerresheim GK, Lindel F, Serrao E, Lesbats P, Engelman AN, Cherepanov P, Lindemann D.

PLoS Pathog. 2016 Oct 10;12(10):e1005956. doi: 10.1371/journal.ppat.1005956. eCollection 2016 Oct.

19.

A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core Domain.

Patel D, Antwi J, Koneru PC, Serrao E, Forli S, Kessl JJ, Feng L, Deng N, Levy RM, Fuchs JR, Olson AJ, Engelman AN, Bauman JD, Kvaratskhelia M, Arnold E.

J Biol Chem. 2016 Nov 4;291(45):23569-23577. Epub 2016 Sep 19.

20.

The Effect of Gene Alterations and Tyrosine Kinase Inhibition on Survival and Cause of Death in Patients With Adenocarcinoma of the Lung and Brain Metastases.

Sperduto PW, Yang TJ, Beal K, Pan H, Brown PD, Bangdiwala A, Shanley R, Yeh N, Gaspar LE, Braunstein S, Sneed P, Boyle J, Kirkpatrick JP, Mak KS, Shih HA, Engelman A, Roberge D, Arvold ND, Alexander B, Awad MM, Contessa J, Chiang V, Hardie J, Ma D, Lou E, Sperduto W, Mehta MP.

Int J Radiat Oncol Biol Phys. 2016 Oct 1;96(2):406-413. doi: 10.1016/j.ijrobp.2016.06.006. Epub 2016 Jun 14.

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