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Items: 1 to 20 of 180

1.

Burst-Like Transcription of Mutant and Wildtype MYH7-Alleles as Possible Origin of Cell-to-Cell Contractile Imbalance in Hypertrophic Cardiomyopathy.

Montag J, Kowalski K, Makul M, Ernstberger P, Radocaj A, Beck J, Becker E, Tripathi S, Keyser B, Mühlfeld C, Wissel K, Pich A, van der Velden J, Dos Remedios CG, Perrot A, Francino A, Navarro-López F, Brenner B, Kraft T.

Front Physiol. 2018 Apr 9;9:359. doi: 10.3389/fphys.2018.00359. eCollection 2018.

2.

Monophosphorylation of cardiac troponin-I at Ser23/24 is sufficient to regulate cardiac myofibrillar Ca2+ sensitivity and calpain-induced proteolysis.

Martin-Garrido A, Biesiadecki BJ, Salhi HE, Shaifta Y, Dos Remedios CG, Ayuz-Guner S, Cai W, Ge Y, Avkiran M, Kentish JC.

J Biol Chem. 2018 Apr 18. pii: jbc.RA117.001292. doi: 10.1074/jbc.RA117.001292. [Epub ahead of print]

3.

Orphan receptor GPR37L1 contributes to the sexual dimorphism of central cardiovascular control.

Coleman JLJ, Mouat MA, Wu J, Jancovski N, Bassi JK, Chan AY, Humphreys DT, Mrad N, Yu ZY, Ngo T, Iismaa S, Dos Remedios CG, Feneley MP, Allen AM, Graham RM, Smith NJ.

Biol Sex Differ. 2018 Apr 6;9(1):14. doi: 10.1186/s13293-018-0173-y.

4.

Skeletal myosin binding protein-C isoforms regulate thin filament activity in a Ca2+-dependent manner.

Lin BL, Li A, Mun JY, Previs MJ, Previs SB, Campbell SG, Dos Remedios CG, Tombe PP, Craig R, Warshaw DM, Sadayappan S.

Sci Rep. 2018 Feb 8;8(1):2604. doi: 10.1038/s41598-018-21053-1.

5.

Differences in Contractile Function of Myofibrils within Human Embryonic Stem Cell-Derived Cardiomyocytes vs. Adult Ventricular Myofibrils Are Related to Distinct Sarcomeric Protein Isoforms.

Iorga B, Schwanke K, Weber N, Wendland M, Greten S, Piep B, Dos Remedios CG, Martin U, Zweigerdt R, Kraft T, Brenner B.

Front Physiol. 2018 Jan 19;8:1111. doi: 10.3389/fphys.2017.01111. eCollection 2017.

6.

Correction to: The Sydney Heart Bank: improving translational research while eliminating or reducing the use of animal models of human heart disease.

Dos Remedios CG, Lal SP, Li A, McNamara J, Keogh A, Macdonald PS, Cooke R, Ehler E, Knöll R, Marston SB, Stelzer J, Granzier H, Bezzina C, van Dijk S, De Man F, Stienen GJM, Odeberg J, Pontén F, Linke WA, van der Velden J.

Biophys Rev. 2018 Feb 1. doi: 10.1007/s12551-018-0397-4. [Epub ahead of print]

7.

Protein phosphatase 5 regulates titin phosphorylation and function at a sarcomere-associated mechanosensor complex in cardiomyocytes.

Krysiak J, Unger A, Beckendorf L, Hamdani N, von Frieling-Salewsky M, Redfield MM, Dos Remedios CG, Sheikh F, Gergs U, Boknik P, Linke WA.

Nat Commun. 2018 Jan 17;9(1):262. doi: 10.1038/s41467-017-02483-3.

8.

An historical perspective of the discovery of titin filaments -Part 2.

Dos Remedios CG.

Biophys Rev. 2018 Jan 13. doi: 10.1007/s12551-017-0393-0. [Epub ahead of print] Review.

9.

Editorial for issue #1 2018.

Dos Remedios CG, Li A.

Biophys Rev. 2018 Feb;10(1):1-2. doi: 10.1007/s12551-017-0385-0. Epub 2017 Dec 26. No abstract available.

10.

Platelet-Derived Growth Factor Receptor-Alpha Expressing Cardiac Progenitor Cells Can Be Derived from Previously Cryopreserved Human Heart Samples.

Le TYL, Pickett HA, Dos Remedios CG, Barbaro PM, Kizana E, Chong JJH.

Stem Cells Dev. 2018 Feb 1;27(3):184-198. doi: 10.1089/scd.2017.0082. Epub 2018 Jan 16.

PMID:
29205098
11.

Abnormal contractility in human heart myofibrils from patients with dilated cardiomyopathy due to mutations in TTN and contractile protein genes.

Vikhorev PG, Smoktunowicz N, Munster AB, Copeland O, Kostin S, Montgiraud C, Messer AE, Toliat MR, Li A, Dos Remedios CG, Lal S, Blair CA, Campbell KS, Guglin M, Knoll R, Marston SB.

Sci Rep. 2017 Nov 1;7(1):14829. doi: 10.1038/s41598-017-13675-8.

12.

Dose-Dependent Effects of the Myosin Activator Omecamtiv Mecarbil on Cross-Bridge Behavior and Force Generation in Failing Human Myocardium.

Mamidi R, Li J, Gresham KS, Verma S, Doh CY, Li A, Lal S, Dos Remedios CG, Stelzer JE.

Circ Heart Fail. 2017 Oct;10(10). pii: e004257. doi: 10.1161/CIRCHEARTFAILURE.117.004257.

PMID:
29030372
13.

Myofilament Remodeling and Function Is More Impaired in Peripartum Cardiomyopathy Compared with Dilated Cardiomyopathy and Ischemic Heart Disease.

Bollen IAE, Ehler E, Fleischanderl K, Bouwman F, Kempers L, Ricke-Hoch M, Hilfiker-Kleiner D, Dos Remedios CG, Krüger M, Vink A, Asselbergs FW, van Spaendonck-Zwarts KY, Pinto YM, Kuster DWD, van der Velden J.

Am J Pathol. 2017 Dec;187(12):2645-2658. doi: 10.1016/j.ajpath.2017.08.022. Epub 2017 Sep 19. Erratum in: Am J Pathol. 2018 Mar;188(3):828-829.

PMID:
28935576
14.

The Sydney Heart Bank: improving translational research while eliminating or reducing the use of animal models of human heart disease.

Dos Remedios CG, Lal SP, Li A, McNamara J, Keogh A, Macdonald PS, Cooke R, Ehler E, Knöll R, Marston SB, Stelzer J, Granzier H, Bezzina C, van Dijk S, De Man F, Stienen GJM, Odeberg J, Pontén F, Linke W, van der Velden J.

Biophys Rev. 2017 Aug;9(4):431-441. doi: 10.1007/s12551-017-0305-3. Epub 2017 Aug 14. Review. Erratum in: Biophys Rev. 2018 Feb 1;:.

15.

Special Issue of Biophysical Reviews dedicated to the 19th IUPAB Conference in Edinburgh, Scotland (July 2017).

Hall D, Dos Remedios CG.

Biophys Rev. 2017 Aug;9(4):269-271. doi: 10.1007/s12551-017-0312-4. Epub 2017 Aug 12.

16.

MYBPC3 mutations are associated with a reduced super-relaxed state in patients with hypertrophic cardiomyopathy.

McNamara JW, Li A, Lal S, Bos JM, Harris SP, van der Velden J, Ackerman MJ, Cooke R, Dos Remedios CG.

PLoS One. 2017 Jun 28;12(6):e0180064. doi: 10.1371/journal.pone.0180064. eCollection 2017.

17.

New insights into real-time multiprotein fluorescence microscopy.

Dos Remedios CG.

Biophys Rev. 2017 Apr;9(2):65-66. doi: 10.1007/s12551-017-0260-z. Epub 2017 Mar 21. No abstract available.

18.

Increased collagen within the transverse tubules in human heart failure.

Crossman DJ, Shen X, Jüllig M, Munro M, Hou Y, Middleditch M, Shrestha D, Li A, Lal S, Dos Remedios CG, Baddeley D, Ruygrok PN, Soeller C.

Cardiovasc Res. 2017 Jul 1;113(8):879-891. doi: 10.1093/cvr/cvx055.

PMID:
28444133
19.

A model of cardiac contraction based on novel measurements of tension development in human cardiomyocytes.

Land S, Park-Holohan SJ, Smith NP, Dos Remedios CG, Kentish JC, Niederer SA.

J Mol Cell Cardiol. 2017 May;106:68-83. doi: 10.1016/j.yjmcc.2017.03.008. Epub 2017 Apr 7.

PMID:
28392437
20.

Long non-coding RNAs link extracellular matrix gene expression to ischemic cardiomyopathy.

Huang ZP, Ding Y, Chen J, Wu G, Kataoka M, Hu Y, Yang JH, Liu J, Drakos SG, Selzman CH, Kyselovic J, Qu LH, Dos Remedios CG, Pu WT, Wang DZ.

Cardiovasc Res. 2016 Aug 24. pii: cvw201. [Epub ahead of print]

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