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Items: 11

1.

Acute Moraxella catarrhalis Airway Infection of Chronically Smoke-Exposed Mice Increases Mechanisms of Emphysema Development: A Pilot Study.

Fischer K, Doehn JM, Herr C, Lachner C, Heinrich A, Kershaw O, Voss M, Jacobson MH, Gruber AD, Clauss M, Witzenrath M, Bals R, Gutbier B, Slevogt H.

Eur J Microbiol Immunol (Bp). 2018 Dec 11;8(4):128-134. doi: 10.1556/1886.2018.00019. eCollection 2018 Dec 23.

2.

Spleen tyrosine kinase inhibition blocks airway constriction and protects from Th2-induced airway inflammation and remodeling.

Tabeling C, Herbert J, Hocke AC, Lamb DJ, Wollin SL, Erb KJ, Boiarina E, Movassagh H, Scheffel J, Doehn JM, Hippenstiel S, Maurer M, Gounni AS, Kuebler WM, Suttorp N, Witzenrath M.

Allergy. 2017 Jul;72(7):1061-1072. doi: 10.1111/all.13101. Epub 2017 Jan 12.

PMID:
27906453
3.

Pentraxin-3 levels in graft-versus-host disease during allogeneic hematopoietic stem cell transplantation.

Doehn JM, Winkler A, Kuzmina Z, Hladik A, Greinix H, Knapp S, Robak O.

Exp Hematol. 2016 Oct;44(10):917-23. doi: 10.1016/j.exphem.2016.07.002. Epub 2016 Jul 9.

PMID:
27403536
4.

PKCα Deficiency in Mice Is Associated with Pulmonary Vascular Hyperresponsiveness to Thromboxane A2 and Increased Thromboxane Receptor Expression.

Tabeling C, Noe E, Naujoks J, Doehn JM, Hippenstiel S, Opitz B, Suttorp N, Klopfleisch R, Witzenrath M.

J Vasc Res. 2015;52(4):279-88. doi: 10.1159/000443402. Epub 2016 Feb 19.

PMID:
26890419
5.

Moraxella catarrhalis induces an immune response in the murine lung that is independent of human CEACAM5 expression and long-term smoke exposure.

Gutbier B, Fischer K, Doehn JM, von Lachner C, Herr C, Klaile E, Frischmann U, Singer BB, Riesbeck K, Zimmermann W, Suttorp N, Bachmann S, Bals R, Witzenrath M, Slevogt H.

Am J Physiol Lung Cell Mol Physiol. 2015 Aug 1;309(3):L250-61. doi: 10.1152/ajplung.00265.2014. Epub 2015 Jun 5.

6.

Role of Pneumococcal Autolysin for KLF4 Expression and Chemokine Secretion in Lung Epithelium.

Zahlten J, Herta T, Kabus C, Steinfeldt M, Kershaw O, García P, Hocke AC, Gruber AD, Hübner RH, Steinicke R, Doehn JM, Suttorp N, Hippenstiel S.

Am J Respir Cell Mol Biol. 2015 Oct;53(4):544-54. doi: 10.1165/rcmb.2014-0024OC.

PMID:
25756955
7.

Streptococcus pneumoniae-Induced Oxidative Stress in Lung Epithelial Cells Depends on Pneumococcal Autolysis and Is Reversible by Resveratrol.

Zahlten J, Kim YJ, Doehn JM, Pribyl T, Hocke AC, García P, Hammerschmidt S, Suttorp N, Hippenstiel S, Hübner RH.

J Infect Dis. 2015 Jun 1;211(11):1822-30. doi: 10.1093/infdis/jiu806. Epub 2014 Dec 15.

PMID:
25512625
8.

Juvenile megaesophagus in PKCα-deficient mice is associated with an increase in the segment of the distal esophagus lined by smooth muscle cells.

Noe E, Tabeling C, Doehn JM, Naujoks J, Opitz B, Hippenstiel S, Witzenrath M, Klopfleisch R.

Ann Anat. 2014 Sep;196(5):365-71. doi: 10.1016/j.aanat.2014.04.001. Epub 2014 May 4.

PMID:
24862691
9.

Delivery of the endolysin Cpl-1 by inhalation rescues mice with fatal pneumococcal pneumonia.

Doehn JM, Fischer K, Reppe K, Gutbier B, Tschernig T, Hocke AC, Fischetti VA, Löffler J, Suttorp N, Hippenstiel S, Witzenrath M.

J Antimicrob Chemother. 2013 Sep;68(9):2111-7. doi: 10.1093/jac/dkt131. Epub 2013 Apr 30.

PMID:
23633685
10.

Streptococcus pneumoniae stimulates a STING- and IFN regulatory factor 3-dependent type I IFN production in macrophages, which regulates RANTES production in macrophages, cocultured alveolar epithelial cells, and mouse lungs.

Koppe U, Högner K, Doehn JM, Müller HC, Witzenrath M, Gutbier B, Bauer S, Pribyl T, Hammerschmidt S, Lohmeyer J, Suttorp N, Herold S, Opitz B.

J Immunol. 2012 Jan 15;188(2):811-7. doi: 10.4049/jimmunol.1004143. Epub 2011 Dec 12.

11.

Systemic use of the endolysin Cpl-1 rescues mice with fatal pneumococcal pneumonia.

Witzenrath M, Schmeck B, Doehn JM, Tschernig T, Zahlten J, Loeffler JM, Zemlin M, Müller H, Gutbier B, Schütte H, Hippenstiel S, Fischetti VA, Suttorp N, Rosseau S.

Crit Care Med. 2009 Feb;37(2):642-9. doi: 10.1097/CCM.0b013e31819586a6.

PMID:
19114881

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