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Best matches for dmt1 parkinson's:

Is the 1254T>C polymorphism in the DMT1 gene associated with Parkinson's disease? Saadat SM et al. Neurosci Lett. (2015)

DMT1 polymorphism and risk of Parkinson's disease. He Q et al. Neurosci Lett. (2011)

The VPS35 gene and Parkinson's disease. Deng H et al. Mov Disord. (2013)

Search results

Items: 1 to 20 of 48

1.

S-nitrosylation of divalent metal transporter 1 enhances iron uptake to mediate loss of dopaminergic neurons and motoric deficit.

Liu C, Zhang CW, Lo SQ, Ang ST, Chew KCM, Yu D, Chai BH, Tan B, Tsang F, Tai YK, Tan BWQ, Liang MC, Tan HT, Tang JY, Lai MKP, Chua JJE, Chung MCM, Khanna S, Lim KL, Soong TW.

J Neurosci. 2018 Aug 13. pii: 3262-17. doi: 10.1523/JNEUROSCI.3262-17.2018. [Epub ahead of print]

PMID:
30104344
2.

Activation of NMDA receptors mediated iron accumulation via modulating iron transporters in Parkinson's disease.

Xu H, Liu X, Xia J, Yu T, Qu Y, Jiang H, Xie J.

FASEB J. 2018 Jun 13:fj201800060RR. doi: 10.1096/fj.201800060RR. [Epub ahead of print]

PMID:
29897813
3.

Ceruloplasmin, a Potential Therapeutic Agent for Alzheimer's Disease.

Zhao YS, Zhang LH, Yu PP, Gou YJ, Zhao J, You LH, Wang ZY, Zheng X, Yan LJ, Yu P, Chang YZ.

Antioxid Redox Signal. 2018 May 10;28(14):1323-1337. doi: 10.1089/ars.2016.6883. Epub 2017 Oct 17.

PMID:
28874056
4.

Transgenic Mice Overexpressing the Divalent Metal Transporter 1 Exhibit Iron Accumulation and Enhanced Parkin Expression in the Brain.

Zhang CW, Tai YK, Chai BH, Chew KCM, Ang ET, Tsang F, Tan BWQ, Hong ETE, Asad ABA, Chuang KH, Lim KL, Soong TW.

Neuromolecular Med. 2017 Sep;19(2-3):375-386. doi: 10.1007/s12017-017-8451-0. Epub 2017 Jul 10.

5.

Interleukin-6 regulates iron-related proteins through c-Jun N-terminal kinase activation in BV2 microglial cell lines.

Zhou S, Du X, Xie J, Wang J.

PLoS One. 2017 Jul 3;12(7):e0180464. doi: 10.1371/journal.pone.0180464. eCollection 2017.

6.

New Insights into the Crosstalk between NMDARs and Iron: Implications for Understanding Pathology of Neurological Diseases.

Xu H, Jiang H, Xie J.

Front Mol Neurosci. 2017 Mar 16;10:71. doi: 10.3389/fnmol.2017.00071. eCollection 2017. Review.

7.

Structural Mechanism for Cargo Recognition by the Retromer Complex.

Lucas M, Gershlick DC, Vidaurrazaga A, Rojas AL, Bonifacino JS, Hierro A.

Cell. 2016 Dec 1;167(6):1623-1635.e14. doi: 10.1016/j.cell.2016.10.056. Epub 2016 Nov 23.

8.

Activation of ATP-sensitive potassium channels enhances DMT1-mediated iron uptake in SK-N-SH cells in vitro.

Du X, Xu H, Shi L, Jiang Z, Song N, Jiang H, Xie J.

Sci Rep. 2016 Sep 20;6:33674. doi: 10.1038/srep33674.

9.

Expression of Iron Transporters and Pathological Hallmarks of Parkinson's and Alzheimer's Diseases in the Brain of Young, Adult, and Aged Rats.

Lu LN, Qian ZM, Wu KC, Yung WH, Ke Y.

Mol Neurobiol. 2017 Sep;54(7):5213-5224. doi: 10.1007/s12035-016-0067-0. Epub 2016 Aug 30.

PMID:
27578012
10.

Deferoxamine-mediated up-regulation of HIF-1α prevents dopaminergic neuronal death via the activation of MAPK family proteins in MPTP-treated mice.

Guo C, Hao LJ, Yang ZH, Chai R, Zhang S, Gu Y, Gao HL, Zhong ML, Wang T, Li JY, Wang ZY.

Exp Neurol. 2016 Jun;280:13-23. doi: 10.1016/j.expneurol.2016.03.016. Epub 2016 Mar 18.

PMID:
26996132
11.

EGCG Protects against 6-OHDA-Induced Neurotoxicity in a Cell Culture Model.

Chen D, Kanthasamy AG, Reddy MB.

Parkinsons Dis. 2015;2015:843906. doi: 10.1155/2015/843906. Epub 2015 Dec 6.

12.

Discovery and characterization of a novel non-competitive inhibitor of the divalent metal transporter DMT1/SLC11A2.

Montalbetti N, Simonin A, Simonin C, Awale M, Reymond JL, Hediger MA.

Biochem Pharmacol. 2015 Aug 1;96(3):216-24. doi: 10.1016/j.bcp.2015.05.002. Epub 2015 Jun 3.

PMID:
26047847
13.

Is the 1254T>C polymorphism in the DMT1 gene associated with Parkinson's disease?

Saadat SM, Değirmenci İ, Özkan S, Saydam F, Özdemir Köroğlu Z, Çolak E, Güneş HV.

Neurosci Lett. 2015 May 6;594:51-4. doi: 10.1016/j.neulet.2015.03.054. Epub 2015 Mar 26.

PMID:
25817364
14.

Ndfip1 attenuated 6-OHDA-induced iron accumulation via regulating the degradation of DMT1.

Jia W, Xu H, Du X, Jiang H, Xie J.

Neurobiol Aging. 2015 Feb;36(2):1183-93. doi: 10.1016/j.neurobiolaging.2014.10.021. Epub 2014 Oct 18.

PMID:
25467637
15.
16.

Hepcidin Suppresses Brain Iron Accumulation by Downregulating Iron Transport Proteins in Iron-Overloaded Rats.

Du F, Qian ZM, Luo Q, Yung WH, Ke Y.

Mol Neurobiol. 2015 Aug;52(1):101-14. doi: 10.1007/s12035-014-8847-x. Epub 2014 Aug 13.

PMID:
25115800
17.

Increased Ndfip1 in the substantia nigra of Parkinsonian brains is associated with elevated iron levels.

Howitt J, Gysbers AM, Ayton S, Carew-Jones F, Putz U, Finkelstein DI, Halliday GM, Tan SS.

PLoS One. 2014 Jan 24;9(1):e87119. doi: 10.1371/journal.pone.0087119. eCollection 2014.

18.

Brain angiotensin regulates iron homeostasis in dopaminergic neurons and microglial cells.

Garrido-Gil P, Rodriguez-Pallares J, Dominguez-Meijide A, Guerra MJ, Labandeira-Garcia JL.

Exp Neurol. 2013 Dec;250:384-96. doi: 10.1016/j.expneurol.2013.10.013. Epub 2013 Oct 30.

PMID:
24184051
19.

Review: iron metabolism and the role of iron in neurodegenerative disorders.

Hadzhieva M, Kirches E, Mawrin C.

Neuropathol Appl Neurobiol. 2014 Apr;40(3):240-57. doi: 10.1111/nan.12096. Review.

PMID:
24164678
20.

6-Hydroxydopamine promotes iron traffic in primary cultured astrocytes.

Zhang HY, Wang ND, Song N, Xu HM, Shi LM, Jiang H, Xie JX.

Biometals. 2013 Oct;26(5):705-14. doi: 10.1007/s10534-013-9647-x. Epub 2013 Jun 17.

PMID:
23771608

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