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Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence.

Fernández E, Collins MO, Frank RAW, Zhu F, Kopanitsa MV, Nithianantharajah J, Lemprière SA, Fricker D, Elsegood KA, McLaughlin CL, Croning MDR, Mclean C, Armstrong JD, Hill WD, Deary IJ, Cencelli G, Bagni C, Fromer M, Purcell SM, Pocklington AJ, Choudhary JS, Komiyama NH, Grant SGN.

Cell Rep. 2017 Oct 17;21(3):679-691. doi: 10.1016/j.celrep.2017.09.045.


Intragenic CNTNAP2 Deletions: A Bridge Too Far?

Poot M.

Mol Syndromol. 2017 May;8(3):118-130. doi: 10.1159/000456021. Epub 2017 Feb 10. Review.


Re-arrangements of gene transcripts at glutamatergic synapses after prolonged treatments with antipsychotics: A putative link with synaptic remodeling.

Buonaguro EF, Iasevoli F, Marmo F, Eramo A, Latte G, Avagliano C, Tomasetti C, de Bartolomeis A.

Prog Neuropsychopharmacol Biol Psychiatry. 2017 Jun 2;76:29-41. doi: 10.1016/j.pnpbp.2017.02.012. Epub 2017 Feb 22.


TAOK2 Kinase Mediates PSD95 Stability and Dendritic Spine Maturation through Septin7 Phosphorylation.

Yadav S, Oses-Prieto JA, Peters CJ, Zhou J, Pleasure SJ, Burlingame AL, Jan LY, Jan YN.

Neuron. 2017 Jan 18;93(2):379-393. doi: 10.1016/j.neuron.2016.12.006. Epub 2017 Jan 5.


Human Rho Guanine Nucleotide Exchange Factor 11 (ARHGEF11) Regulates Dendritic Morphogenesis.

Mizuki Y, Takaki M, Sakamoto S, Okamoto S, Kishimoto M, Okahisa Y, Itoh M, Yamada N.

Int J Mol Sci. 2016 Dec 29;18(1). pii: E67. doi: 10.3390/ijms18010067.


Pathological Basis for Deficient Excitatory Drive to Cortical Parvalbumin Interneurons in Schizophrenia.

Chung DW, Fish KN, Lewis DA.

Am J Psychiatry. 2016 Nov 1;173(11):1131-1139. Epub 2016 Jul 22.


Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

Li J, Wilkinson B, Clementel VA, Hou J, O'Dell TJ, Coba MP.

Sci Signal. 2016 Aug 9;9(440):rs8. doi: 10.1126/scisignal.aaf6716.


Resequencing and Association Analysis of Six PSD-95-Related Genes as Possible Susceptibility Genes for Schizophrenia and Autism Spectrum Disorders.

Xing J, Kimura H, Wang C, Ishizuka K, Kushima I, Arioka Y, Yoshimi A, Nakamura Y, Shiino T, Oya-Ito T, Takasaki Y, Uno Y, Okada T, Iidaka T, Aleksic B, Mori D, Ozaki N.

Sci Rep. 2016 Jun 7;6:27491. doi: 10.1038/srep27491.


Switching antipsychotics: Imaging the differential effect on the topography of postsynaptic density transcripts in antipsychotic-naïve vs. antipsychotic-exposed rats.

de Bartolomeis A, Marmo F, Buonaguro EF, Latte G, Tomasetti C, Iasevoli F.

Prog Neuropsychopharmacol Biol Psychiatry. 2016 Oct 3;70:24-38. doi: 10.1016/j.pnpbp.2016.04.015. Epub 2016 May 10.


Changes in cholinergic and glutamatergic markers in the striatum from a sub-set of subjects with schizophrenia.

Dean B, Thomas N, Lai CY, Chen WJ, Scarr E.

Schizophr Res. 2015 Dec;169(1-3):83-88. doi: 10.1016/j.schres.2015.10.028. Epub 2015 Nov 3.


Molecular evidence for decreased synaptic efficacy in the postmortem olfactory bulb of individuals with schizophrenia.

Egbujo CN, Sinclair D, Borgmann-Winter KE, Arnold SE, Turetsky BI, Hahn CG.

Schizophr Res. 2015 Oct;168(1-2):554-62. doi: 10.1016/j.schres.2015.07.026. Epub 2015 Aug 7.


Changes in cortical N-methyl-D-aspartate receptors and post-synaptic density protein 95 in schizophrenia, mood disorders and suicide.

Dean B, Gibbons AS, Boer S, Uezato A, Meador-Woodruff J, Scarr E, McCullumsmith RE.

Aust N Z J Psychiatry. 2016 Mar;50(3):275-83. doi: 10.1177/0004867415586601. Epub 2015 May 26.


D-aspartate dysregulation in Ddo(-/-) mice modulates phencyclidine-induced gene expression changes of postsynaptic density molecules in cortex and striatum.

de Bartolomeis A, Errico F, Aceto G, Tomasetti C, Usiello A, Iasevoli F.

Prog Neuropsychopharmacol Biol Psychiatry. 2015 Oct 1;62:35-43. doi: 10.1016/j.pnpbp.2015.05.003. Epub 2015 May 12.


Functional Uncoupling NMDAR NR2A Subunit from PSD-95 in the Prefrontal Cortex: Effects on Behavioral Dysfunction and Parvalbumin Loss after Early-Life Stress.

Ganguly P, Holland FH, Brenhouse HC.

Neuropsychopharmacology. 2015 Nov;40(12):2666-75. doi: 10.1038/npp.2015.134. Epub 2015 May 8. Erratum in: Neuropsychopharmacology. 2016 Mar;41(4):1188.


Evidence for schizophrenia as a disorder of neuroplasticity.

McCullumsmith RE.

Am J Psychiatry. 2015 Apr;172(4):312-3. doi: 10.1176/appi.ajp.2015.15010069. No abstract available.


Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis.

Fossati G, Morini R, Corradini I, Antonucci F, Trepte P, Edry E, Sharma V, Papale A, Pozzi D, Defilippi P, Meier JC, Brambilla R, Turco E, Rosenblum K, Wanker EE, Ziv NE, Menna E, Matteoli M.

Cell Death Differ. 2015 Sep;22(9):1425-36. doi: 10.1038/cdd.2014.227. Epub 2015 Feb 13.


Progressive recruitment of cortical and striatal regions by inducible postsynaptic density transcripts after increasing doses of antipsychotics with different receptor profiles: insights for psychosis treatment.

de Bartolomeis A, Iasevoli F, Marmo F, Buonaguro EF, Eramo A, Rossi R, Avvisati L, Latte G, Tomasetti C.

Eur Neuropsychopharmacol. 2015 Apr;25(4):566-82. doi: 10.1016/j.euroneuro.2015.01.003. Epub 2015 Jan 15.


Synaptic proteins in the hippocampus indicative of increased neuronal activity in CA3 in schizophrenia.

Li W, Ghose S, Gleason K, Begovic A, Perez J, Bartko J, Russo S, Wagner AD, Selemon L, Tamminga CA.

Am J Psychiatry. 2015 Apr;172(4):373-82. doi: 10.1176/appi.ajp.2014.14010123. Epub 2015 Jan 13. Erratum in: Am J Psychiatry. 2015 May;172(5):488.


Reductions in synaptic proteins and selective alteration of prepulse inhibition in male C57BL/6 mice after postnatal administration of a VIP receptor (VIPR2) agonist.

Ago Y, Condro MC, Tan YV, Ghiani CA, Colwell CS, Cushman JD, Fanselow MS, Hashimoto H, Waschek JA.

Psychopharmacology (Berl). 2015 Jun;232(12):2181-9. doi: 10.1007/s00213-014-3848-z. Epub 2015 Jan 11.

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