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Items: 1 to 20 of 218

1.

"Marker of Self" CD47 on lentiviral vectors decreases macrophage-mediated clearance and increases delivery to SIRPA-expressing lung carcinoma tumors.

Sosale NG, Ivanovska II, Tsai RK, Swift J, Hsu JW, Alvey CM, Zoltick PW, Discher DE.

Mol Ther Methods Clin Dev. 2016 Dec 7;3:16080. doi: 10.1038/mtm.2016.80.

2.

Mechanosensing by the nucleus: From pathways to scaling relationships.

Cho S, Irianto J, Discher DE.

J Cell Biol. 2017 Jan 2. pii: jcb.201610042. doi: 10.1083/jcb.201610042. [Epub ahead of print] Review.

PMID:
28043971
3.

DNA Damage Follows Repair Factor Depletion and Portends Genome Variation in Cancer Cells after Pore Migration.

Irianto J, Xia Y, Pfeifer CR, Athirasala A, Ji J, Alvey C, Tewari M, Bennett RR, Harding SM, Liu AJ, Greenberg RA, Discher DE.

Curr Biol. 2016 Dec 9. pii: S0960-9822(16)31403-8. doi: 10.1016/j.cub.2016.11.049. [Epub ahead of print]

PMID:
27989676
4.

Matrix rigidity regulates the microtubule network polarization in migration.

Raab M, Discher DE.

Cytoskeleton (Hoboken). 2016 Dec 9. doi: 10.1002/cm.21349. [Epub ahead of print]

PMID:
27935261
5.

Nuclear constriction segregates mobile nuclear proteins away from chromatin.

Irianto J, Pfeifer CR, Bennett RR, Xia Y, Ivanovska IL, Liu AJ, Greenberg RA, Discher DE.

Mol Biol Cell. 2016 Dec 15;27(25):4011-4020.

PMID:
27798234
6.

Nuclear lamins in cancer.

Irianto J, Pfeifer CR, Ivanovska IL, Swift J, Discher DE.

Cell Mol Bioeng. 2016 Jun;9(2):258-267.

PMID:
27570565
7.

Leishmania major Infection-Induced VEGF-A/VEGFR-2 Signaling Promotes Lymphangiogenesis That Controls Disease.

Weinkopff T, Konradt C, Christian DA, Discher DE, Hunter CA, Scott P.

J Immunol. 2016 Sep 1;197(5):1823-31. doi: 10.4049/jimmunol.1600717.

PMID:
27474074
8.

Mechanical signaling coordinates the embryonic heartbeat.

Chiou KK, Rocks JW, Chen CY, Cho S, Merkus KE, Rajaratnam A, Robison P, Tewari M, Vogel K, Majkut SF, Prosser BL, Discher DE, Liu AJ.

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):8939-44. doi: 10.1073/pnas.1520428113.

PMID:
27457951
9.

SnapShot: Mechanosensing Matrix.

Irianto J, Pfeifer CR, Xia Y, Discher DE.

Cell. 2016 Jun 16;165(7):1820-1820.e1. doi: 10.1016/j.cell.2016.06.002.

PMID:
27315485
10.

Filomicelles from aromatic diblock copolymers increase paclitaxel-induced tumor cell death and aneuploidy compared with aliphatic copolymers.

Nair PR, Karthick SA, Spinler KR, Vakili MR, Lavasanifar A, Discher DE.

Nanomedicine (Lond). 2016 Jun;11(12):1551-69. doi: 10.2217/nnm-2016-0007.

PMID:
27177319
11.

The reason sickle reticulocytes expose PS.

Discher DE, Ney PA.

Blood. 2015 Oct 8;126(15):1737-8. doi: 10.1182/blood-2015-08-665117.

12.

Macrophage engulfment of a cell or nanoparticle is regulated by unavoidable opsonization, a species-specific 'Marker of Self' CD47, and target physical properties.

Sosale NG, Spinler KR, Alvey C, Discher DE.

Curr Opin Immunol. 2015 Aug;35:107-12. doi: 10.1016/j.coi.2015.06.013. Review.

13.

Fractal heterogeneity in minimal matrix models of scars modulates stiff-niche stem-cell responses via nuclear exit of a mechanorepressor.

Dingal PC, Bradshaw AM, Cho S, Raab M, Buxboim A, Swift J, Discher DE.

Nat Mater. 2015 Sep;14(9):951-60. doi: 10.1038/nmat4350.

14.

Stem cell mechanobiology: diverse lessons from bone marrow.

Ivanovska IL, Shin JW, Swift J, Discher DE.

Trends Cell Biol. 2015 Sep;25(9):523-32. doi: 10.1016/j.tcb.2015.04.003. Review.

16.

Cell motion and mechanobiology.

Paluch EK, Discher DE.

Mol Biol Cell. 2015 Mar 15;26(6):1011. doi: 10.1091/mbc.E14-12-1590. No abstract available.

17.

Substrate stiffness-modulated registry phase correlations in cardiomyocytes map structural order to coherent beating.

Dasbiswas K, Majkut S, Discher DE, Safran SA.

Nat Commun. 2015 Jan 19;6:6085. doi: 10.1038/ncomms7085.

PMID:
25597833
18.

Simple insoluble cues specify stem cell differentiation.

Dingal PC, Wells RG, Discher DE.

Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18104-5. doi: 10.1073/pnas.1421562112. No abstract available.

19.

Systems mechanobiology: tension-inhibited protein turnover is sufficient to physically control gene circuits.

Dingal PC, Discher DE.

Biophys J. 2014 Dec 2;107(11):2734-43. doi: 10.1016/j.bpj.2014.10.042.

20.

Cell rigidity and shape override CD47's "self"-signaling in phagocytosis by hyperactivating myosin-II.

Sosale NG, Rouhiparkouhi T, Bradshaw AM, Dimova R, Lipowsky R, Discher DE.

Blood. 2015 Jan 15;125(3):542-52. doi: 10.1182/blood-2014-06-585299.

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