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Items: 1 to 20 of 38


The PDE4 cAMP-Specific Phosphodiesterases: Targets for Drugs with Antidepressant and Memory-Enhancing Action.

Bolger GB.

Adv Neurobiol. 2017;17:63-102. doi: 10.1007/978-3-319-58811-7_4. Review.


Depressive-like phenotype induced by prenatal dexamethasone in mice is reversed by desipramine.

Conti M, Spulber S, Raciti M, Ceccatelli S.

Neuropharmacology. 2017 Nov;126:242-249. doi: 10.1016/j.neuropharm.2017.09.015. Epub 2017 Sep 13.


Role of DISC1 in Neuronal Trafficking and its Implication in Neuropsychiatric Manifestation and Neurotherapeutics.

Tomoda T, Hikida T, Sakurai T.

Neurotherapeutics. 2017 Jul;14(3):623-629. doi: 10.1007/s13311-017-0556-5. Review.


Rare disruptive variants in the DISC1 Interactome and Regulome: association with cognitive ability and schizophrenia.

Teng S, Thomson PA, McCarthy S, Kramer M, Muller S, Lihm J, Morris S, Soares DC, Hennah W, Harris S, Camargo LM, Malkov V, McIntosh AM, Millar JK, Blackwood DH, Evans KL, Deary IJ, Porteous DJ, McCombie WR.

Mol Psychiatry. 2018 May;23(5):1270-1277. doi: 10.1038/mp.2017.115. Epub 2017 Jun 20.


Expression of Disrupted-in-schizophrenia 1 in Hippocampus in Postpartum Depression Animal Models Induced by Pre-pregnancy Stress.

Xia B, Chen C, Zhang H, Zhou X, Tao W, Wu H, Chen G.

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2017 Apr 20;39(2):230-235. doi: 10.3881/j.issn.1000-503X.2017.02.011.


Effects of a Balanced Translocation between Chromosomes 1 and 11 Disrupting the DISC1 Locus on White Matter Integrity.

Whalley HC, Dimitrova R, Sprooten E, Dauvermann MR, Romaniuk L, Duff B, Watson AR, Moorhead B, Bastin M, Semple SI, Giles S, Hall J, Thomson P, Roberts N, Hughes ZA, Brandon NJ, Dunlop J, Whitcher B, Blackwood DH, McIntosh AM, Lawrie SM.

PLoS One. 2015 Jun 23;10(6):e0130900. doi: 10.1371/journal.pone.0130900. eCollection 2015.


Venlafaxine increases cell proliferation and regulates DISC1, PDE4B and NMDA receptor 2B expression in the hippocampus in chronic mild stress mice.

Zhang X, Li X, Li M, Ren J, Yun K, An Y, Lin L, Zhang H.

Eur J Pharmacol. 2015 May 15;755:58-65. doi: 10.1016/j.ejphar.2015.02.044. Epub 2015 Mar 11.


Disturbance of oligodendrocyte function plays a key role in the pathogenesis of schizophrenia and major depressive disorder.

Miyata S, Hattori T, Shimizu S, Ito A, Tohyama M.

Biomed Res Int. 2015;2015:492367. doi: 10.1155/2015/492367. Epub 2015 Feb 1. Review.


DISC1 gene and affective psychopathology: a combined structural and functional MRI study.

Opmeer EM, van Tol MJ, Kortekaas R, van der Wee NJ, Woudstra S, van Buchem MA, Penninx BW, Veltman DJ, Aleman A.

J Psychiatr Res. 2015 Feb;61:150-7. doi: 10.1016/j.jpsychires.2014.11.014. Epub 2014 Dec 11.


Disc1 variation leads to specific alterations in adult neurogenesis.

Chandran JS, Kazanis I, Clapcote SJ, Ogawa F, Millar JK, Porteous DJ, Ffrench-Constant C.

PLoS One. 2014 Oct 1;9(10):e108088. doi: 10.1371/journal.pone.0108088. eCollection 2014.


DISC1-TSNAX and DAOA genes in major depression and citalopram efficacy.

Arias B, Fabbri C, Serretti A, Drago A, Mitjans M, Gastó C, Catalán R, Fañanás L.

J Affect Disord. 2014 Oct;168:91-7. doi: 10.1016/j.jad.2014.06.048. Epub 2014 Jul 5.


No evidence of DISC1-associated morphological changes in the hippocampus, anterior cingulate cortex, or striatum in major depressive disorder cases and healthy controls.

Stacey D, Redlich R, Opel N, Grotegerd D, Arolt V, Kugel H, Heindel W, Baune BT, Dannlowski U.

J Affect Disord. 2014 Sep;166:103-7. doi: 10.1016/j.jad.2014.05.001. Epub 2014 May 11.


Inhibition of protein translation by the DISC1-Boymaw fusion gene from a Scottish family with major psychiatric disorders.

Ji B, Higa KK, Kim M, Zhou L, Young JW, Geyer MA, Zhou X.

Hum Mol Genet. 2014 Nov 1;23(21):5683-705. doi: 10.1093/hmg/ddu285. Epub 2014 Jun 6.


Disrupted in schizophrenia 1 modulates medial prefrontal cortex pyramidal neuron activity through cAMP regulation of transient receptor potential C and small-conductance K+ channels.

El-Hassar L, Simen AA, Duque A, Patel KD, Kaczmarek LK, Arnsten AF, Yeckel MF.

Biol Psychiatry. 2014 Sep 15;76(6):476-85. doi: 10.1016/j.biopsych.2013.12.019. Epub 2014 Jan 20.


708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits.

Thomson PA, Parla JS, McRae AF, Kramer M, Ramakrishnan K, Yao J, Soares DC, McCarthy S, Morris SW, Cardone L, Cass S, Ghiban E, Hennah W, Evans KL, Rebolini D, Millar JK, Harris SE, Starr JM, MacIntyre DJ; Generation Scotland, McIntosh AM, Watson JD, Deary IJ, Visscher PM, Blackwood DH, McCombie WR, Porteous DJ.

Mol Psychiatry. 2014 Jun;19(6):668-75. doi: 10.1038/mp.2013.68. Epub 2013 Jun 4.


Association of DISC1 variants with age of onset in a population-based sample of recurrent major depression.

Thomson PA, MacIntyre DJ, Hamilton G, Dominiczak A, Smith BH, Morris A, Evans KL, Porteous DJ.

Mol Psychiatry. 2013 Jul;18(7):745-7. doi: 10.1038/mp.2012.117. Epub 2012 Aug 7. No abstract available.


Molecular genetics of the psychosis phenotype.

DeRosse P, Malhotra AK, Lencz T.

Can J Psychiatry. 2012 Jul;57(7):446-53. Review.


Social defeat interacts with Disc1 mutations in the mouse to affect behavior.

Haque FN, Lipina TV, Roder JC, Wong AH.

Behav Brain Res. 2012 Aug 1;233(2):337-44. doi: 10.1016/j.bbr.2012.05.037. Epub 2012 May 30.


The DISC1 promoter: characterization and regulation by FOXP2.

Walker RM, Hill AE, Newman AC, Hamilton G, Torrance HS, Anderson SM, Ogawa F, Derizioti P, Nicod J, Vernes SC, Fisher SE, Thomson PA, Porteous DJ, Evans KL.

Hum Mol Genet. 2012 Jul 1;21(13):2862-72. doi: 10.1093/hmg/dds111. Epub 2012 Mar 20.


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