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Best matches for depression sigma receptor:

Sigma-1 receptor chaperone and brain-derived neurotrophic factor: emerging links between cardiovascular disease and depression. Hashimoto K et al. Prog Neurobiol. (2013)

Sigma-1 receptor: the novel intracellular target of neuropsychotherapeutic drugs. Hayashi T et al. J Pharmacol Sci. (2015)

Sigma receptor modulators: a patent review. Collina S et al. Expert Opin Ther Pat. (2013)

Search results

Items: 1 to 20 of 208

1.

Chronic stimulation of the Sigma-1 receptor ameliorates autonomic nerve dysfunction and atrial fibrillation susceptibility in rat models of depression.

Liu X, Qu C, Yang H, Shi S, Zhang C, Zhang Y, Liang J, Yang B.

Am J Physiol Heart Circ Physiol. 2018 Sep 14. doi: 10.1152/ajpheart.00607.2017. [Epub ahead of print]

PMID:
30216117
2.

Potential independent action of sigma receptor ligands through inhibition of the Kv2.1 channel.

Liu X, Fu Y, Yang H, Mavlyutov T, Li J, McCurdy CR, Guo LW, Pattnaik BR.

Oncotarget. 2017 Jul 26;8(35):59345-59358. doi: 10.18632/oncotarget.19581. eCollection 2017 Aug 29.

3.

Hyperactivity of Hypothalamic-Pituitary-Adrenal Axis Due to Dysfunction of the Hypothalamic Glucocorticoid Receptor in Sigma-1 Receptor Knockout Mice.

Di T, Zhang S, Hong J, Zhang T, Chen L.

Front Mol Neurosci. 2017 Sep 6;10:287. doi: 10.3389/fnmol.2017.00287. eCollection 2017.

4.

Deuterated (d6)-dextromethorphan elicits antidepressant-like effects in mice.

Nguyen L, Scandinaro AL, Matsumoto RR.

Pharmacol Biochem Behav. 2017 Oct;161:30-37. doi: 10.1016/j.pbb.2017.09.005. Epub 2017 Sep 12.

PMID:
28916283
5.

Efficacy and Safety of MIN-101: A 12-Week Randomized, Double-Blind, Placebo-Controlled Trial of a New Drug in Development for the Treatment of Negative Symptoms in Schizophrenia.

Davidson M, Saoud J, Staner C, Noel N, Luthringer E, Werner S, Reilly J, Schaffhauser JY, Rabinowitz J, Weiser M, Luthringer R.

Am J Psychiatry. 2017 Dec 1;174(12):1195-1202. doi: 10.1176/appi.ajp.2017.17010122. Epub 2017 Jul 28.

PMID:
28750582
6.
7.

Psychopharmacology of combined activation of the serotonin1A and σ1 receptors.

Ago Y, Hasebe S, Hiramatsu N, Hashimoto H, Takuma K, Matsuda T.

Eur J Pharmacol. 2017 Aug 15;809:172-177. doi: 10.1016/j.ejphar.2017.05.035. Epub 2017 May 18. Review.

PMID:
28529139
8.

Dextromethorphan/quinidine pharmacotherapy in patients with treatment resistant depression: A proof of concept clinical trial.

Murrough JW, Wade E, Sayed S, Ahle G, Kiraly DD, Welch A, Collins KA, Soleimani L, Iosifescu DV, Charney DS.

J Affect Disord. 2017 Aug 15;218:277-283. doi: 10.1016/j.jad.2017.04.072. Epub 2017 Apr 29.

PMID:
28478356
9.

Stimulation of the Sigma-1 Receptor and the Effects on Neurogenesis and Depressive Behaviors in Mice.

Fukunaga K, Moriguchi S.

Adv Exp Med Biol. 2017;964:201-211. doi: 10.1007/978-3-319-50174-1_14. Review.

PMID:
28315273
10.

Sigma-1 Receptors Fine-Tune the Neuronal Networks.

Tsai SA, Su TP.

Adv Exp Med Biol. 2017;964:79-83. doi: 10.1007/978-3-319-50174-1_7. Review.

11.

Introduction to Sigma Receptors: Their Role in Disease and as Therapeutic Targets.

Smith SB.

Adv Exp Med Biol. 2017;964:1-4. doi: 10.1007/978-3-319-50174-1_1. Review.

PMID:
28315260
12.

The Impact of a Single Nucleotide Polymorphism in SIGMAR1 on Depressive Symptoms in Major Depressive Disorder and Bipolar Disorder.

Mandelli L, Wang SM, Han C, Lee SJ, Patkar AA, Masand PS, Pae CU, Serretti A.

Adv Ther. 2017 Mar;34(3):713-724. doi: 10.1007/s12325-017-0482-2. Epub 2017 Jan 31.

PMID:
28144920
13.

Sigma-1 receptor deficiency reduces GABAergic inhibition in the basolateral amygdala leading to LTD impairment and depressive-like behaviors.

Zhang B, Wang L, Chen T, Hong J, Sha S, Wang J, Xiao H, Chen L.

Neuropharmacology. 2017 Apr;116:387-398. doi: 10.1016/j.neuropharm.2017.01.014. Epub 2017 Jan 17.

PMID:
28108357
14.

CREB decreases astrocytic excitability by modifying subcellular calcium fluxes via the sigma-1 receptor.

Eraso-Pichot A, Larramona-Arcas R, Vicario-Orri E, Villalonga R, Pardo L, Galea E, Masgrau R.

Cell Mol Life Sci. 2017 Mar;74(5):937-950. doi: 10.1007/s00018-016-2397-5. Epub 2016 Oct 19.

PMID:
27761593
15.

Corticosteroids Mediate Heart Failure-Induced Depression through Reduced σ1-Receptor Expression.

Shinoda Y, Tagashira H, Bhuiyan MS, Hasegawa H, Kanai H, Zhang C, Han F, Fukunaga K.

PLoS One. 2016 Oct 14;11(10):e0163992. doi: 10.1371/journal.pone.0163992. eCollection 2016.

17.

Pharmacological Investigations of the Dissociative 'Legal Highs' Diphenidine, Methoxphenidine and Analogues.

Wallach J, Kang H, Colestock T, Morris H, Bortolotto ZA, Collingridge GL, Lodge D, Halberstadt AL, Brandt SD, Adejare A.

PLoS One. 2016 Jun 17;11(6):e0157021. doi: 10.1371/journal.pone.0157021. eCollection 2016.

18.

Pimavanserin: An Inverse Agonist Antipsychotic Drug.

Howland RH.

J Psychosoc Nurs Ment Health Serv. 2016 Jun 1;54(6):21-4. doi: 10.3928/02793695-20160523-01.

PMID:
27245248
19.

[Stimulation of sigma-1 receptor ameliorates depressive-like behaviors via mitochondrial ATP production in CaMKIV null mice].

Moriguchi S, Fukunaga K.

Nihon Yakurigaku Zasshi. 2016 Apr;147(4):206-10. doi: 10.1254/fpj.147.206. Japanese. No abstract available.

PMID:
27063903
20.

Crystal structure of the human σ1 receptor.

Schmidt HR, Zheng S, Gurpinar E, Koehl A, Manglik A, Kruse AC.

Nature. 2016 Apr 28;532(7600):527-30. doi: 10.1038/nature17391. Epub 2016 Apr 4.

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