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Chondroitin sulfate efficacy versus celecoxib on knee osteoarthritis structural changes using magnetic resonance imaging: a 2-year multicentre exploratory study.

Pelletier JP, Raynauld JP, Beaulieu AD, Bessette L, Morin F, de Brum-Fernandes AJ, Delorme P, Dorais M, Paiement P, Abram F, Martel-Pelletier J.

Arthritis Res Ther. 2016 Nov 3;18(1):256.


Serum levels of 14-3-3η protein supplement C-reactive protein and rheumatoid arthritis-associated antibodies to predict clinical and radiographic outcomes in a prospective cohort of patients with recent-onset inflammatory polyarthritis.

Carrier N, Marotta A, de Brum-Fernandes AJ, Liang P, Masetto A, Ménard HA, Maksymowych WP, Boire G.

Arthritis Res Ther. 2016 Feb 1;18:37. doi: 10.1186/s13075-016-0935-z.


Anti-carbamylated Protein Antibody Levels Correlate with Anti-Sa (Citrullinated Vimentin) Antibody Levels in Rheumatoid Arthritis.

Challener GJ, Jones JD, Pelzek AJ, Hamilton BJ, Boire G, de Brum-Fernandes AJ, Masetto A, Carrier N, Ménard HA, Silverman GJ, Rigby WF.

J Rheumatol. 2016 Feb;43(2):273-81. doi: 10.3899/jrheum.150179. Epub 2015 Dec 15.


Depressive symptoms predict future simple disease activity index scores and simple disease activity index remission in a prospective cohort of patients with early inflammatory polyarthritis.

Leblanc-Trudeau C, Dobkin PL, Carrier N, Cossette P, de Brum-Fernandes AJ, Liang P, Masetto A, Boire G.

Rheumatology (Oxford). 2015 Dec;54(12):2205-14. doi: 10.1093/rheumatology/kev272. Epub 2015 Jul 25.


Serum C-X-C motif chemokine 13 is elevated in early and established rheumatoid arthritis and correlates with rheumatoid factor levels.

Jones JD, Hamilton BJ, Challener GJ, de Brum-Fernandes AJ, Cossette P, Liang P, Masetto A, Ménard HA, Carrier N, Boyle DL, Rosengren S, Boire G, Rigby WF.

Arthritis Res Ther. 2014 Apr 25;16(2):R103. doi: 10.1186/ar4552.


Cytosolic phospholipase A2 and eicosanoids modulate life, death and function of human osteoclasts in vitro.

Allard-Chamard H, Dufort P, Haroun S, de Brum-Fernandes AJ.

Prostaglandins Leukot Essent Fatty Acids. 2014 Apr;90(4):117-23. doi: 10.1016/j.plefa.2013.12.009. Epub 2014 Jan 1.


Secreted phospholipase A2 type II is present in Paget's disease of bone and modulates osteoclastogenesis, apoptosis and bone resorption of human osteoclasts independently of its catalytic activity in vitro.

Allard-Chamard H, Haroun S, de Brum-Fernandes AJ.

Prostaglandins Leukot Essent Fatty Acids. 2014 Feb-Mar;90(2-3):39-45. doi: 10.1016/j.plefa.2013.12.007. Epub 2013 Dec 27.


Prostaglandin D(2) induces apoptosis of human osteoclasts through ERK1/2 and Akt signaling pathways.

Yue L, Haroun S, Parent JL, de Brum-Fernandes AJ.

Bone. 2014 Mar;60:112-21. doi: 10.1016/j.bone.2013.12.011. Epub 2013 Dec 15.


Predictors of pain for patients with early inflammatory polyarthritis.

Dobkin PL, Liu A, Abrahamowicz M, Carrier N, de Brum-Fernandes AJ, Cossette P, Boire G.

Arthritis Care Res (Hoboken). 2013 Jun;65(6):992-9. doi: 10.1002/acr.21923.


Monocytes from patients with osteoarthritis display increased osteoclastogenesis and bone resorption: the In Vitro Osteoclast Differentiation in Arthritis study.

Durand M, Komarova SV, Bhargava A, Trebec-Reynolds DP, Li K, Fiorino C, Maria O, Nabavi N, Manolson MF, Harrison RE, Dixon SJ, Sims SM, Mizianty MJ, Kurgan L, Haroun S, Boire G, de Fatima Lucena-Fernandes M, de Brum-Fernandes AJ.

Arthritis Rheum. 2013 Jan;65(1):148-58. doi: 10.1002/art.37722.


Prostaglandin D2 induces apoptosis of human osteoclasts by activating the CRTH2 receptor and the intrinsic apoptosis pathway.

Yue L, Durand M, Lebeau Jacob MC, Hogan P, McManus S, Roux S, de Brum-Fernandes AJ.

Bone. 2012 Sep;51(3):338-46. doi: 10.1016/j.bone.2012.06.003. Epub 2012 Jun 12.


Utility and feasibility of musculoskeletal ultrasonography (MSK US) in rheumatology practice in Canada: needs assessment.

Larché MJ, McDonald-Blumer H, Bruns A, Roth J, Khy V, de Brum-Fernandes AJ, Wakefield RJ, Brown AK, Bykerk V.

Clin Rheumatol. 2011 Oct;30(10):1277-83. doi: 10.1007/s10067-011-1743-0. Epub 2011 Apr 12.


The increased in vitro osteoclastogenesis in patients with rheumatoid arthritis is due to increased percentage of precursors and decreased apoptosis - the In Vitro Osteoclast Differentiation in Arthritis (IODA) study.

Durand M, Boire G, Komarova SV, Dixon SJ, Sims SM, Harrison RE, Nabavi N, Maria O, Manolson MF, Mizianty M, Kurgan L, de Brum-Fernandes AJ.

Bone. 2011 Mar 1;48(3):588-96. doi: 10.1016/j.bone.2010.10.167. Epub 2010 Oct 17.


Outcomes in recent-onset inflammatory polyarthritis differ according to initial titers, persistence over time, and specificity of the autoantibodies.

Guzian MC, Carrier N, Cossette P, de Brum-Fernandes AJ, Liang P, Ménard HA, Boire G.

Arthritis Care Res (Hoboken). 2010 Nov;62(11):1624-32. doi: 10.1002/acr.20288. Epub 2010 Jul 8.


Increased concentrations of prostaglandin D2 during post-fracture bone remodeling.

Gallant MA, Chamoux E, Bisson M, Wolsen C, Parent JL, Roux S, de Brum-Fernandes AJ.

J Rheumatol. 2010 Mar;37(3):644-9. doi: 10.3899/jrheum.090622. Epub 2010 Jan 15.


Characterization of C-terminal tail determinants involved in CRTH2 receptor trafficking: identification of a recycling motif.

Roy SJ, Parent A, Gallant MA, de Brum-Fernandes AJ, Stanková J, Parent JL.

Eur J Pharmacol. 2010 Mar 25;630(1-3):10-8. doi: 10.1016/j.ejphar.2009.12.022. Epub 2009 Dec 24.


CD40-activated B cells from patients with systemic lupus erythematosus can be modulated by therapeutic immunoglobulins in vitro.

Néron S, Boire G, Dussault N, Racine C, de Brum-Fernandes AJ, Côté S, Jacques A.

Arch Immunol Ther Exp (Warsz). 2009 Nov-Dec;57(6):447-58. doi: 10.1007/s00005-009-0048-3. Epub 2009 Oct 29.


Cardiovascular safety of celecoxib in acute myocardial infarction patients: a nested case-control study.

Vanasse A, de Brum-Fernandes AJ, Courteau J.

Heart Int. 2009 Jun 30;4(1):e10. doi: 10.4081/hi.2009.e10.


Evaluation of the antitumoral effect of dihydrocucurbitacin-B in both in vitro and in vivo models.

Siqueira JM, Gazola AC, Farias MR, Volkov L, Rivard N, de Brum-Fernandes AJ, Ribeiro-do-Valle RM.

Cancer Chemother Pharmacol. 2009 Aug;64(3):529-38. doi: 10.1007/s00280-008-0901-9. Epub 2009 Jan 30.


Prostaglandin D2 receptors control osteoclastogenesis and the activity of human osteoclasts.

Durand M, Gallant MA, de Brum-Fernandes AJ.

J Bone Miner Res. 2008 Jul;23(7):1097-105. doi: 10.1359/jbmr.080228.

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