Format
Sort by
Items per page

Send to

Choose Destination

Best matches for dca dichloroacetate and cancer:

Therapeutic applications of dichloroacetate and the role of glutathione transferase zeta-1. James MO et al. Pharmacol Ther. (2017)

Dichloroacetate and metformin synergistically suppress the growth of ovarian cancer cells. Li B et al. Oncotarget. (2016)

Dichloroacetate and cancer: new home for an orphan drug? Kankotia S et al. Biochim Biophys Acta. (2014)

Search results

Items: 1 to 20 of 216

1.

Dichloroacetate Affects Mitochondrial Function and Stemness-Associated Properties in Pancreatic Cancer Cell Lines.

Tataranni T, Agriesti F, Pacelli C, Ruggieri V, Laurenzana I, Mazzoccoli C, Sala GD, Panebianco C, Pazienza V, Capitanio N, Piccoli C.

Cells. 2019 May 18;8(5). pii: E478. doi: 10.3390/cells8050478.

2.

Targeting Energy Metabolism by a Platinum(IV) Prodrug as an Alternative Pathway for Cancer Suppression.

Jin S, Guo Y, Song D, Zhu Z, Zhang Z, Sun Y, Yang T, Guo Z, Wang X.

Inorg Chem. 2019 May 6;58(9):6507-6516. doi: 10.1021/acs.inorgchem.9b00708. Epub 2019 Apr 23.

PMID:
31013065
3.

Metabolic stress controls mutant p53 R248Q stability in acute myeloid leukemia cells.

Allende-Vega N, Villalba M.

Sci Rep. 2019 Apr 4;9(1):5637. doi: 10.1038/s41598-019-42220-y.

4.

Time-dependent cytotoxicity of dichloroacetate and metformin against Lewis lung carcinoma.

Kolesnik DL, Pyaskovskaya ON, Yakshibaeva YR, Solyanik GI.

Exp Oncol. 2019 Mar;41(1):14-19.

PMID:
30932416
5.

Aerobic Glycolysis Is Required for Spatial Memory Acquisition But Not Memory Retrieval in Mice.

Harris RA, Lone A, Lim H, Martinez F, Frame AK, Scholl TJ, Cumming RC.

eNeuro. 2019 Feb 22;6(1). pii: ENEURO.0389-18.2019. doi: 10.1523/ENEURO.0389-18.2019. eCollection 2019 Jan-Feb.

6.

Dichloroacetate is an antimetabolite that antagonizes acetate and deprives cancer cells from its benefits: A novel evidence-based medical hypothesis.

El Sayed SM, Baghdadi H, Ahmed NS, Almaramhy HH, Mahmoud AA, El-Sawy SA, Ayat M, Elshazley M, Abdel-Aziz W, Abdel-Latif HM, Ibrahim W, Aboonq MS.

Med Hypotheses. 2019 Jan;122:206-209. doi: 10.1016/j.mehy.2018.11.012. Epub 2018 Nov 22.

PMID:
30593413
7.

Propranolol Promotes Glucose Dependence and Synergizes with Dichloroacetate for Anti-Cancer Activity in HNSCC.

Lucido CT, Miskimins WK, Vermeer PD.

Cancers (Basel). 2018 Nov 30;10(12). pii: E476. doi: 10.3390/cancers10120476.

8.

Sodium Dichloroacetate Pharmacological Effect as Related to Na-K-2Cl Cotransporter Inhibition in Rats.

Stanevičiūtė J, Juknevičienė M, Palubinskienė J, Balnytė I, Valančiūtė A, Vosyliūtė R, Sužiedėlis K, Lesauskaitė V, Stakišaitis D.

Dose Response. 2018 Nov 20;16(4):1559325818811522. doi: 10.1177/1559325818811522. eCollection 2018 Oct-Dec.

9.

Coupling Dichloroacetate Treatment with Curcumin Significantly Enhances Anticancer Potential.

Kan PC, Chang YJ, Chien CS, Su CY, Fang HW.

Anticancer Res. 2018 Nov;38(11):6253-6261. doi: 10.21873/anticanres.12981.

PMID:
30396945
10.

Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells.

Verma A, Lam YM, Leung YC, Hu X, Chen X, Cheung E, Tam KY.

J Pharm Pharmacol. 2019 Mar;71(3):306-315. doi: 10.1111/jphp.13033. Epub 2018 Oct 25.

PMID:
30362115
11.
12.

Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer.

Yang Z, Zhang SL, Hu X, Tam KY.

Eur J Pharmacol. 2018 Nov 5;838:41-52. doi: 10.1016/j.ejphar.2018.09.016. Epub 2018 Sep 10.

PMID:
30213498
13.

Surface-Functionalization of Zr-Fumarate MOF for Selective Cytotoxicity and Immune System Compatibility in Nanoscale Drug Delivery.

Abánades Lázaro I, Haddad S, Rodrigo-Muñoz JM, Marshall RJ, Sastre B, Del Pozo V, Fairen-Jimenez D, Forgan RS.

ACS Appl Mater Interfaces. 2018 Sep 19;10(37):31146-31157. doi: 10.1021/acsami.8b11652. Epub 2018 Sep 5.

PMID:
30136840
14.

Half-sandwich Os(ii) and Ru(ii) bathophenanthroline complexes: anticancer drug candidates with unusual potency and a cellular activity profile in highly invasive triple-negative breast cancer cells.

Pracharova J, Novohradsky V, Kostrhunova H, Štarha P, Trávníček Z, Kasparkova J, Brabec V.

Dalton Trans. 2018 Sep 11;47(35):12197-12208. doi: 10.1039/c8dt02236d.

PMID:
30112527
15.
16.

The Role of Pyruvate Dehydrogenase Kinase-4 (PDK4) in Bladder Cancer and Chemoresistance.

Woolbright BL, Choudhary D, Mikhalyuk A, Trammel C, Shanmugam S, Abbott E, Pilbeam CC, Taylor JA 3rd.

Mol Cancer Ther. 2018 Sep;17(9):2004-2012. doi: 10.1158/1535-7163.MCT-18-0063. Epub 2018 Jun 15.

PMID:
29907593
17.

Targeted reversal and phosphorescence lifetime imaging of cancer cell metabolism via a theranostic rhenium(I)-DCA conjugate.

Yang J, Cao Q, Zhang H, Hao L, Zhou D, Gan Z, Li Z, Tong YX, Ji LN, Mao ZW.

Biomaterials. 2018 Sep;176:94-105. doi: 10.1016/j.biomaterials.2018.05.040. Epub 2018 May 25.

PMID:
29870900
18.

Age-Related Changes in Expression and Activity of Human Hepatic Mitochondrial Glutathione Transferase Zeta1.

Zhong G, James MO, Smeltz MG, Jahn SC, Langaee T, Simpson P, Stacpoole PW.

Drug Metab Dispos. 2018 Aug;46(8):1118-1128. doi: 10.1124/dmd.118.081810. Epub 2018 May 31.

PMID:
29853471
19.

Dichloroacetate enhances the antitumor efficacy of chemotherapeutic agents via inhibiting autophagy in non-small-cell lung cancer.

Lu X, Zhou D, Hou B, Liu QX, Chen Q, Deng XF, Yu ZB, Dai JG, Zheng H.

Cancer Manag Res. 2018 May 16;10:1231-1241. doi: 10.2147/CMAR.S156530. eCollection 2018.

20.

Dual-acting antitumor Pt(iv) prodrugs of kiteplatin with dichloroacetate axial ligands.

Savino S, Gandin V, Hoeschele JD, Marzano C, Natile G, Margiotta N.

Dalton Trans. 2018 May 29;47(21):7144-7158. doi: 10.1039/c8dt00686e.

PMID:
29766157

Supplemental Content

Loading ...
Support Center