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Items: 1 to 20 of 96

1.

DNA methylation landscape of the genes regulating D-serine and D-aspartate metabolism in post-mortem brain from controls and subjects with schizophrenia.

Keller S, Punzo D, Cuomo M, Affinito O, Coretti L, Sacchi S, Florio E, Lembo F, Carella M, Copetti M, Cocozza S, Balu DT, Errico F, Usiello A, Chiariotti L.

Sci Rep. 2018 Jul 5;8(1):10163. doi: 10.1038/s41598-018-28332-x.

2.

Prediction Analysis for Transition to Schizophrenia in Individuals at Clinical High Risk for Psychosis: The Relationship of DAO, DAOA, and NRG1 Variants with Negative Symptoms and Cognitive Deficits.

Jagannath V, Theodoridou A, Gerstenberg M, Franscini M, Heekeren K, Correll CU, Rössler W, Grünblatt E, Walitza S.

Front Psychiatry. 2017 Dec 20;8:292. doi: 10.3389/fpsyt.2017.00292. eCollection 2017.

3.

Human d-amino acid oxidase: The inactive G183R variant.

Murtas G, Caldinelli L, Cappelletti P, Sacchi S, Pollegioni L.

Biochim Biophys Acta Proteins Proteom. 2018 Jul;1866(7):822-830. doi: 10.1016/j.bbapap.2017.12.007. Epub 2017 Dec 21.

PMID:
29274788
4.

Cellular Phenotypes in Human iPSC-Derived Neurons from a Genetic Model of Autism Spectrum Disorder.

Deshpande A, Yadav S, Dao DQ, Wu ZY, Hokanson KC, Cahill MK, Wiita AP, Jan YN, Ullian EM, Weiss LA.

Cell Rep. 2017 Dec 5;21(10):2678-2687. doi: 10.1016/j.celrep.2017.11.037.

5.
6.

A systematic meta-analysis of the association of Neuregulin 1 (NRG1), D-amino acid oxidase (DAO), and DAO activator (DAOA)/G72 polymorphisms with schizophrenia.

Jagannath V, Gerstenberg M, Correll CU, Walitza S, Grünblatt E.

J Neural Transm (Vienna). 2018 Jan;125(1):89-102. doi: 10.1007/s00702-017-1782-z. Epub 2017 Sep 1.

PMID:
28864885
7.

Assessment of the Target Engagement and D-Serine Biomarker Profiles of the D-Amino Acid Oxidase Inhibitors Sodium Benzoate and PGM030756.

Howley E, Bestwick M, Fradley R, Harrison H, Leveridge M, Okada K, Fieldhouse C, Farnaby W, Canning H, Sykes AP, Merchant K, Hazel K, Kerr C, Kinsella N, Walsh L, Livermore DG, Hoffman I, Ellery J, Mitchell P, Patel T, Carlton M, Barnes M, Miller DJ.

Neurochem Res. 2017 Nov;42(11):3279-3288. doi: 10.1007/s11064-017-2367-9. Epub 2017 Aug 5.

PMID:
28780732
8.

Elucidation of inhibitor-binding pockets of d-amino acid oxidase using docking simulation and N-sulfanylethylanilide-based labeling technology.

Kohiki T, Kato Y, Nishikawa Y, Yorita K, Sagawa I, Denda M, Inokuma T, Shigenaga A, Fukui K, Otaka A.

Org Biomol Chem. 2017 Jun 27;15(25):5289-5297. doi: 10.1039/c7ob00633k.

PMID:
28509930
9.

The DAOA gene is associated with schizophrenia in the Taiwanese population.

Chu CS, Chow PC, Cohen-Woods S, Gaysina D, Tang KY, McGuffin P.

Psychiatry Res. 2017 Jun;252:201-207. doi: 10.1016/j.psychres.2017.03.013. Epub 2017 Mar 7.

PMID:
28285246
10.
11.

Reduced levels of Cacna1c attenuate mesolimbic dopamine system function.

Terrillion CE, Dao DT, Cachope R, Lobo MK, Puche AC, Cheer JF, Gould TD.

Genes Brain Behav. 2017 Jun;16(5):495-505. doi: 10.1111/gbb.12371. Epub 2017 Mar 13.

12.

Structure models of G72, the product of a susceptibility gene to schizophrenia.

Kato Y, Fukui K.

J Biochem. 2017 Feb 1;161(2):223-230. doi: 10.1093/jb/mvw064.

PMID:
27815320
13.

Regulating levels of the neuromodulator d-serine in human brain: structural insight into pLG72 and d-amino acid oxidase interaction.

Birolo L, Sacchi S, Smaldone G, Molla G, Leo G, Caldinelli L, Pirone L, Eliometri P, Di Gaetano S, Orefice I, Pedone E, Pucci P, Pollegioni L.

FEBS J. 2016 Sep;283(18):3353-70. doi: 10.1111/febs.13809. Epub 2016 Aug 5.

14.

Effect of risperidone on plasma d-serine concentration in rats post-administered with d-serine.

Onozato M, Nakazawa H, Hakariya H, Shishikura M, Nagashima C, Ishimaru K, Sakamoto T, Iizuka H, Ichiba H, Fukushima T.

Life Sci. 2016 Aug 1;158:98-103. doi: 10.1016/j.lfs.2016.06.021. Epub 2016 Jun 25.

PMID:
27352936
15.

Ultimate Translation: Developing Therapeutics Targeting on N-Methyl-d-Aspartate Receptor.

Tsai GE.

Adv Pharmacol. 2016;76:257-309. doi: 10.1016/bs.apha.2016.03.003. Epub 2016 May 24. Review.

PMID:
27288080
16.

Haplotypes of the D-Amino Acid Oxidase Gene Are Significantly Associated with Schizophrenia and Its Neurocognitive Deficits.

Liu YL, Wang SC, Hwu HG, Fann CS, Yang UC, Yang WC, Hsu PC, Chang CC, Wen CC, Tsai-Wu JJ, Hwang TJ, Hsieh MH, Liu CC, Chien YL, Fang CP, Faraone SV, Tsuang MT, Chen WJ, Liu CM.

PLoS One. 2016 Mar 17;11(3):e0150435. doi: 10.1371/journal.pone.0150435. eCollection 2016.

17.

Searching for cognitive enhancement in the Morris water maze: better and worse performance in D-amino acid oxidase knockout (Dao(-/-)) mice.

Pritchett D, Taylor AM, Barkus C, Engle SJ, Brandon NJ, Sharp T, Foster RG, Harrison PJ, Peirson SN, Bannerman DM.

Eur J Neurosci. 2016 Apr;43(7):979-89. doi: 10.1111/ejn.13192. Epub 2016 Mar 23.

18.

Genome-wide significant linkage of schizophrenia-related neuroanatomical trait to 12q24.

Sprooten E, Gupta CN, Knowles EE, McKay DR, Mathias SR, Curran JE, Kent JW Jr, Carless MA, Almeida MA, Dyer TD, Göring HH, Olvera RL, Kochunov P, Fox PT, Duggirala R, Almasy L, Calhoun VD, Blangero J, Turner JA, Glahn DC.

Am J Med Genet B Neuropsychiatr Genet. 2015 Dec;168(8):678-86. doi: 10.1002/ajmg.b.32360. Epub 2015 Oct 5.

19.

A high-performance liquid chromatography assay with a triazole-bonded column for evaluation of d-amino acid oxidase activity.

Iwasaki M, Kashiwaguma Y, Nagashima C, Izumi M, Uekusa A, Iwasa S, Onozato M, Ichiba H, Fukushima T.

Biomed Chromatogr. 2016 Mar;30(3):384-9. doi: 10.1002/bmc.3559. Epub 2015 Aug 27.

PMID:
26174062
20.

Adaptive evolution and elucidating the potential inhibitor against schizophrenia to target DAOA (G72) isoforms.

Sehgal SA, Mannan S, Kanwal S, Naveed I, Mir A.

Drug Des Devel Ther. 2015 Jul 3;9:3471-80. doi: 10.2147/DDDT.S63946. eCollection 2015.

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