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Items: 1 to 20 of 344

1.

Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28.

Wang L, Rowe RG, Jaimes A, Yu C, Nam Y, Pearson DS, Zhang J, Xie X, Marion W, Heffron GJ, Daley GQ, Sliz P.

Cell Rep. 2018 Jun 5;23(10):3091-3101. doi: 10.1016/j.celrep.2018.04.116.

2.

A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development.

Cesana M, Guo MH, Cacchiarelli D, Wahlster L, Barragan J, Doulatov S, Vo LT, Salvatori B, Trapnell C, Clement K, Cahan P, Tsanov KM, Sousa PM, Tazon-Vega B, Bolondi A, Giorgi FM, Califano A, Rinn JL, Meissner A, Hirschhorn JN, Daley GQ.

Cell Stem Cell. 2018 Apr 5;22(4):575-588.e7. doi: 10.1016/j.stem.2018.03.012.

PMID:
29625070
3.

Reconstruction of complex single-cell trajectories using CellRouter.

Lummertz da Rocha E, Rowe RG, Lundin V, Malleshaiah M, Jha DK, Rambo CR, Li H, North TE, Collins JJ, Daley GQ.

Nat Commun. 2018 Mar 1;9(1):892. doi: 10.1038/s41467-018-03214-y.

4.

Regulation of embryonic haematopoietic multipotency by EZH1.

Vo LT, Kinney MA, Liu X, Zhang Y, Barragan J, Sousa PM, Jha DK, Han A, Cesana M, Shao Z, North TE, Orkin SH, Doulatov S, Xu J, Daley GQ.

Nature. 2018 Jan 25;553(7689):506-510. doi: 10.1038/nature25435. Epub 2018 Jan 17.

5.

Comprehensive Mapping of Pluripotent Stem Cell Metabolism Using Dynamic Genome-Scale Network Modeling.

Chandrasekaran S, Zhang J, Sun Z, Zhang L, Ross CA, Huang YC, Asara JM, Li H, Daley GQ, Collins JJ.

Cell Rep. 2017 Dec 5;21(10):2965-2977. doi: 10.1016/j.celrep.2017.07.048.

6.

Is There Merit in Merit Aid?

Ziegelstein RC, Prober CG, Minor LB, Daley GQ, Rothman PB, Hundert EM.

N Engl J Med. 2017 Dec 21;377(25):2415-2417. doi: 10.1056/NEJMp1713146. Epub 2017 Oct 25. No abstract available.

PMID:
29069550
7.

Using CRISPR-Cas9 to Generate Gene-Corrected Autologous iPSCs for the Treatment of Inherited Retinal Degeneration.

Burnight ER, Gupta M, Wiley LA, Anfinson KR, Tran A, Triboulet R, Hoffmann JM, Klaahsen DL, Andorf JL, Jiao C, Sohn EH, Adur MK, Ross JW, Mullins RF, Daley GQ, Schlaeger TM, Stone EM, Tucker BA.

Mol Ther. 2017 Sep 6;25(9):1999-2013. doi: 10.1016/j.ymthe.2017.05.015. Epub 2017 Jun 12.

8.

Haematopoietic stem and progenitor cells from human pluripotent stem cells.

Sugimura R, Jha DK, Han A, Soria-Valles C, da Rocha EL, Lu YF, Goettel JA, Serrao E, Rowe RG, Malleshaiah M, Wong I, Sousa P, Zhu TN, Ditadi A, Keller G, Engelman AN, Snapper SB, Doulatov S, Daley GQ.

Nature. 2017 May 25;545(7655):432-438. doi: 10.1038/nature22370. Epub 2017 May 17.

9.

Reassembling embryos in vitro from component stem cells.

Kubaczka C, Daley GQ.

Cell Res. 2017 Aug;27(8):961-962. doi: 10.1038/cr.2017.61. Epub 2017 Apr 21. Review.

10.

Autophagy: It's in Your Blood.

Doulatov S, Daley GQ.

Dev Cell. 2017 Mar 27;40(6):518-520. doi: 10.1016/j.devcel.2017.03.011.

11.

Polar Extremes in the Clinical Use of Stem Cells.

Daley GQ.

N Engl J Med. 2017 Mar 16;376(11):1075-1077. doi: 10.1056/NEJMe1701379. No abstract available.

PMID:
28296612
12.

Signaling through RNA-binding proteins as a cell fate regulatory mechanism.

Tsanov KM, Daley GQ.

Cell Cycle. 2017 Apr 18;16(8):723-724. doi: 10.1080/15384101.2017.1302205. Epub 2017 Mar 8. No abstract available.

13.

Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors.

Doulatov S, Vo LT, Macari ER, Wahlster L, Kinney MA, Taylor AM, Barragan J, Gupta M, McGrath K, Lee HY, Humphries JM, DeVine A, Narla A, Alter BP, Beggs AH, Agarwal S, Ebert BL, Gazda HT, Lodish HF, Sieff CA, Schlaeger TM, Zon LI, Daley GQ.

Sci Transl Med. 2017 Feb 8;9(376). pii: eaah5645. doi: 10.1126/scitranslmed.aah5645.

14.

Disruptive reproductive technologies.

Cohen IG, Daley GQ, Adashi EY.

Sci Transl Med. 2017 Jan 11;9(372). pii: eaag2959. doi: 10.1126/scitranslmed.aag2959.

PMID:
28077678
15.

Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity.

Lu YF, Cahan P, Ross S, Sahalie J, Sousa PM, Hadland BK, Cai W, Serrao E, Engelman AN, Bernstein ID, Daley GQ.

Cell Rep. 2016 Dec 20;17(12):3178-3192. doi: 10.1016/j.celrep.2016.11.077.

16.

LIN28 phosphorylation by MAPK/ERK couples signalling to the post-transcriptional control of pluripotency.

Tsanov KM, Pearson DS, Wu Z, Han A, Triboulet R, Seligson MT, Powers JT, Osborne JK, Kane S, Gygi SP, Gregory RI, Daley GQ.

Nat Cell Biol. 2017 Jan;19(1):60-67. doi: 10.1038/ncb3453. Epub 2016 Dec 19.

17.

Stem cells: Valine starvation leads to a hungry niche.

Rowe RG, Daley GQ.

Nature. 2017 Jan 12;541(7636):166-167. doi: 10.1038/nature21106. Epub 2016 Dec 14. No abstract available.

18.

Progress towards generation of human haematopoietic stem cells.

Wahlster L, Daley GQ.

Nat Cell Biol. 2016 Nov;18(11):1111-1117. doi: 10.1038/ncb3419. Epub 2016 Oct 10. Review.

PMID:
27723718
19.

TGF-╬▓ inhibitors stimulate red blood cell production by enhancing self-renewal of BFU-E erythroid progenitors.

Gao X, Lee HY, da Rocha EL, Zhang C, Lu YF, Li D, Feng Y, Ezike J, Elmes RR, Barrasa MI, Cahan P, Li H, Daley GQ, Lodish HF.

Blood. 2016 Dec 8;128(23):2637-2641. Epub 2016 Oct 24.

20.

The LIN28B/let-7 axis is a novel therapeutic pathway in multiple myeloma.

Manier S, Powers JT, Sacco A, Glavey SV, Huynh D, Reagan MR, Salem KZ, Moschetta M, Shi J, Mishima Y, Roche-Lestienne C, Leleu X, Roccaro AM, Daley GQ, Ghobrial IM.

Leukemia. 2017 Apr;31(4):853-860. doi: 10.1038/leu.2016.296. Epub 2016 Oct 24.

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