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Items: 1 to 20 of 62

1.

Prph2 initiates outer segment morphogenesis but maturation requires Prph2/Rom1 oligomerization.

Conley SM, Stuck MW, Watson JN, Zulliger R, Burnett JL, Naash MI.

Hum Mol Genet. 2019 Feb 1;28(3):459-475. doi: 10.1093/hmg/ddy359.

PMID:
30307502
2.

Differential composition of DHA and very-long-chain PUFAs in rod and cone photoreceptors.

Agbaga MP, Merriman DK, Brush RS, Lydic TA, Conley SM, Naash MI, Jackson S, Woods AS, Reid GE, Busik JV, Anderson RE.

J Lipid Res. 2018 Sep;59(9):1586-1596. doi: 10.1194/jlr.M082495. Epub 2018 Jul 9.

PMID:
29986998
3.

Oligomerization of Prph2 and Rom1 is essential for photoreceptor outer segment formation.

Zulliger R, Conley SM, Mwoyosvi ML, Al-Ubaidi MR, Naash MI.

Hum Mol Genet. 2018 Oct 15;27(20):3507-3518. doi: 10.1093/hmg/ddy240.

PMID:
29961824
4.

IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging.

Fulop GA, Ramirez-Perez FI, Kiss T, Tarantini S, Valcarcel Ares MN, Toth P, Yabluchanskiy A, Conley SM, Ballabh P, Martinez-Lemus LA, Ungvari Z, Csiszar A.

J Gerontol A Biol Sci Med Sci. 2019 Mar 14;74(4):446-454. doi: 10.1093/gerona/gly144.

PMID:
29931048
5.

DNA nanoparticles are safe and nontoxic in non-human primate eyes.

Kelley RA, Conley SM, Makkia R, Watson JN, Han Z, Cooper MJ, Naash MI.

Int J Nanomedicine. 2018 Mar 8;13:1361-1379. doi: 10.2147/IJN.S157000. eCollection 2018.

6.

Rom1 converts Y141C-Prph2-associated pattern dystrophy to retinitis pigmentosa.

Conley SM, Stuck MW, Watson JN, Naash MI.

Hum Mol Genet. 2017 Feb 1;26(3):509-518. doi: 10.1093/hmg/ddw408.

7.

The K153Del PRPH2 mutation differentially impacts photoreceptor structure and function.

Chakraborty D, Conley SM, Zulliger R, Naash MI.

Hum Mol Genet. 2016 Aug 15;25(16):3500-3514. doi: 10.1093/hmg/ddw193. Epub 2016 Jun 29.

8.

Role of RDS and Rhodopsin in Cngb1-Related Retinal Degeneration.

Chakraborty D, Conley SM, Pittler SJ, Naash MI.

Invest Ophthalmol Vis Sci. 2016 Mar;57(3):787-97. doi: 10.1167/iovs.15-18516.

9.

PRPH2/RDS and ROM-1: Historical context, current views and future considerations.

Stuck MW, Conley SM, Naash MI.

Prog Retin Eye Res. 2016 May;52:47-63. doi: 10.1016/j.preteyeres.2015.12.002. Epub 2016 Jan 8. Review.

10.

Varying the GARP2-to-RDS Ratio Leads to Defects in Rim Formation and Rod and Cone Function.

Chakraborty D, Conley SM, DeRamus ML, Pittler SJ, Naash MI.

Invest Ophthalmol Vis Sci. 2015 Dec;56(13):8187-98. doi: 10.1167/iovs.15-17785.

11.

Non-viral therapeutic approaches to ocular diseases: An overview and future directions.

Zulliger R, Conley SM, Naash MI.

J Control Release. 2015 Dec 10;219:471-487. doi: 10.1016/j.jconrel.2015.10.007. Epub 2015 Oct 9. Review.

12.

Characterization of Ribozymes Targeting a Congenital Night Blindness Mutation in Rhodopsin Mutation.

Conley SM, Whalen P, Lewin AS, Naash MI.

Adv Exp Med Biol. 2016;854:509-15. doi: 10.1007/978-3-319-17121-0_68.

PMID:
26427453
13.

Therapeutic Approach of Nanotechnology for Oxidative Stress Induced Ocular Neurodegenerative Diseases.

Mitra RN, Conley SM, Naash MI.

Adv Exp Med Biol. 2016;854:463-9. doi: 10.1007/978-3-319-17121-0_62.

PMID:
26427447
14.

RDS Functional Domains and Dysfunction in Disease.

Stuck MW, Conley SM, Naash MI.

Adv Exp Med Biol. 2016;854:217-22. doi: 10.1007/978-3-319-17121-0_29. Review.

PMID:
26427414
15.

Retinal Degeneration Slow (RDS) Glycosylation Plays a Role in Cone Function and in the Regulation of RDS┬ĚROM-1 Protein Complex Formation.

Stuck MW, Conley SM, Naash MI.

J Biol Chem. 2015 Nov 13;290(46):27901-13. doi: 10.1074/jbc.M115.683698. Epub 2015 Sep 29.

16.

SNAREs Interact with Retinal Degeneration Slow and Rod Outer Segment Membrane Protein-1 during Conventional and Unconventional Outer Segment Targeting.

Zulliger R, Conley SM, Mwoyosvi ML, Stuck MW, Azadi S, Naash MI.

PLoS One. 2015 Sep 25;10(9):e0138508. doi: 10.1371/journal.pone.0138508. eCollection 2015.

17.

Genomic DNA nanoparticles rescue rhodopsin-associated retinitis pigmentosa phenotype.

Han Z, Banworth MJ, Makkia R, Conley SM, Al-Ubaidi MR, Cooper MJ, Naash MI.

FASEB J. 2015 Jun;29(6):2535-44. doi: 10.1096/fj.15-270363. Epub 2015 Feb 24.

18.

Gene therapy for PRPH2-associated ocular disease: challenges and prospects.

Conley SM, Naash MI.

Cold Spring Harb Perspect Med. 2014 Aug 28;4(11):a017376. doi: 10.1101/cshperspect.a017376. Review.

19.

Yttrium oxide nanoparticles prevent photoreceptor death in a light-damage model of retinal degeneration.

Mitra RN, Merwin MJ, Han Z, Conley SM, Al-Ubaidi MR, Naash MI.

Free Radic Biol Med. 2014 Oct;75:140-8. doi: 10.1016/j.freeradbiomed.2014.07.013. Epub 2014 Jul 24.

20.

The Y141C knockin mutation in RDS leads to complex phenotypes in the mouse.

Stuck MW, Conley SM, Naash MI.

Hum Mol Genet. 2014 Dec 1;23(23):6260-74. doi: 10.1093/hmg/ddu345. Epub 2014 Jul 7.

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