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Topical drug therapeutics for neuropathic pain.

Coderre TJ.

Expert Opin Pharmacother. 2018 Aug;19(11):1211-1220. doi: 10.1080/14656566.2018.1501026. Epub 2018 Jul 25. Review.


Mild Social Stress in Mice Produces Opioid-Mediated Analgesia in Visceral but Not Somatic Pain States.

Pitcher MH, Gonzalez-Cano R, Vincent K, Lehmann M, Cobos EJ, Coderre TJ, Baeyens JM, Cervero F.

J Pain. 2017 Jun;18(6):716-725. doi: 10.1016/j.jpain.2017.02.422. Epub 2017 Feb 20.


Spinal intracellular metabotropic glutamate receptor 5 (mGluR5) contributes to pain and c-fos expression in a rat model of inflammatory pain.

Vincent K, Wang SF, Laferrière A, Kumar N, Coderre TJ.

Pain. 2017 Apr;158(4):705-716. doi: 10.1097/j.pain.0000000000000823.


Consistent sex-dependent effects of PKMζ gene ablation and pharmacological inhibition on the maintenance of referred pain.

Nasir H, Mahboubi H, Gyawali S, Ding S, Mickeviciute A, Ragavendran JV, Laferrière A, Stochaj U, Coderre TJ.

Mol Pain. 2016 Nov 29;12. pii: 1744806916675347. Print 2016.


A Cyclic Tetrapeptide ("Cyclodal") and Its Mirror-Image Isomer Are Both High-Affinity μ Opioid Receptor Antagonists.

Weltrowska G, Nguyen TM, Chung NN, Wood J, Ma X, Guo J, Wilkes BC, Ge Y, Laferrière A, Coderre TJ, Schiller PW.

J Med Chem. 2016 Oct 13;59(19):9243-9254. doi: 10.1021/acs.jmedchem.6b01200. Epub 2016 Oct 3.


Effects of topical combinations of clonidine and pentoxifylline on capsaicin-induced allodynia and postcapsaicin tourniquet-induced pain in healthy volunteers: a double-blind, randomized, controlled study.

Ragavendran JV, Laferrière A, Bennett GJ, Ware MA, Gandhi W, Bley K, Schweinhardt P, Coderre TJ.

Pain. 2016 Oct;157(10):2366-74. doi: 10.1097/j.pain.0000000000000659.


Intracellular mGluR5 plays a critical role in neuropathic pain.

Vincent K, Cornea VM, Jong YJ, Laferrière A, Kumar N, Mickeviciute A, Fung JS, Bandegi P, Ribeiro-da-Silva A, O'Malley KL, Coderre TJ.

Nat Commun. 2016 Feb 3;7:10604. doi: 10.1038/ncomms10604.


The bifunctional μ opioid agonist/antioxidant [Dmt(1)]DALDA is a superior analgesic in an animal model of complex regional pain syndrome-type i.

Schiller PW, Nguyen TM, Saray A, Poon AW, Laferrière A, Coderre TJ.

ACS Chem Neurosci. 2015 Nov 18;6(11):1789-93. doi: 10.1021/acschemneuro.5b00228. Epub 2015 Sep 14.


Topical combinations to treat microvascular dysfunction of chronic postischemia pain.

Laferrière A, Abaji R, Tsai CY, Ragavendran JV, Coderre TJ.

Anesth Analg. 2014 Apr;118(4):830-40. doi: 10.1213/ANE.0000000000000141.


Pentoxifylline reduces chronic post-ischaemia pain by alleviating microvascular dysfunction.

Ragavendran JV, Laferrière A, Khorashadi M, Coderre TJ.

Eur J Pain. 2014 Mar;18(3):406-14. doi: 10.1002/j.1532-2149.2013.00381.x. Epub 2013 Jul 31.


Glycemia-dependent nuclear factor κB activation contributes to mechanical allodynia in rats with chronic postischemia pain.

Ross-Huot MC, Laferrière A, Khorashadi M, Coderre TJ.

Anesthesiology. 2013 Sep;119(3):687-97. doi: 10.1097/ALN.0b013e318299980c.


Systemic pregabalin attenuates facial hypersensitivity and noxious stimulus-evoked release of glutamate in medullary dorsal horn in a rodent model of trigeminal neuropathic pain.

Kumar N, Cherkas PS, Varathan V, Miyamoto M, Chiang CY, Dostrovsky JO, Sessle BJ, Coderre TJ.

Neurochem Int. 2013 May;62(6):831-5. doi: 10.1016/j.neuint.2013.02.022. Epub 2013 Feb 26.


Topical combinations aimed at treating microvascular dysfunction reduce allodynia in rat models of CRPS-I and neuropathic pain.

Ragavendran JV, Laferrière A, Xiao WH, Bennett GJ, Padi SS, Zhang J, Coderre TJ.

J Pain. 2013 Jan;14(1):66-78. doi: 10.1016/j.jpain.2012.10.004.


Involvement of ATP in noxious stimulus-evoked release of glutamate in rat medullary dorsal horn: a microdialysis study.

Kumar N, Cherkas PS, Chiang CY, Dostrovsky JO, Sessle BJ, Coderre TJ.

Neurochem Int. 2012 Dec;61(8):1276-9. doi: 10.1016/j.neuint.2012.10.004. Epub 2012 Oct 15.


Systemic pregabalin attenuates sensorimotor responses and medullary glutamate release in inflammatory tooth pain model.

Narita N, Kumar N, Cherkas PS, Chiang CY, Dostrovsky JO, Coderre TJ, Sessle BJ.

Neuroscience. 2012 Aug 30;218:359-66. doi: 10.1016/j.neuroscience.2012.05.016. Epub 2012 May 17.


PKMζ is essential for spinal plasticity underlying the maintenance of persistent pain.

Laferrière A, Pitcher MH, Haldane A, Huang Y, Cornea V, Kumar N, Sacktor TC, Cervero F, Coderre TJ.

Mol Pain. 2011 Dec 20;7:99. doi: 10.1186/1744-8069-7-99.


Effects of glycemic regulation on chronic postischemia pain.

Ross-Huot MC, Laferrière A, Gi CM, Khorashadi M, Schricker T, Coderre TJ.

Anesthesiology. 2011 Sep;115(3):614-25. doi: 10.1097/ALN.0b013e31822a63c9.


Role of peripheral endothelin receptors in an animal model of complex regional pain syndrome type 1 (CRPS-I).

Millecamps M, Laferrière A, Ragavendran JV, Stone LS, Coderre TJ.

Pain. 2010 Oct;151(1):174-83. doi: 10.1016/j.pain.2010.07.003. Epub 2010 Aug 1.


Complex regional pain syndrome: what's in a name?

Coderre TJ.

J Pain. 2011 Jan;12(1):2-12. doi: 10.1016/j.jpain.2010.06.001. Epub 2010 Jul 15.

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