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Items: 20


A polyphenol-rich fraction obtained from table grapes decreases adiposity, insulin resistance and markers of inflammation and impacts gut microbiota in high-fat-fed mice.

Collins B, Hoffman J, Martinez K, Grace M, Lila MA, Cockrell C, Nadimpalli A, Chang E, Chuang CC, Zhong W, Mackert J, Shen W, Cooney P, Hopkins R, McIntosh M.

J Nutr Biochem. 2016 May;31:150-65. doi: 10.1016/j.jnutbio.2015.12.021. Epub 2016 Feb 26.


Table grape consumption reduces adiposity and markers of hepatic lipogenesis and alters gut microbiota in butter fat-fed mice.

Baldwin J, Collins B, Wolf PG, Martinez K, Shen W, Chuang CC, Zhong W, Cooney P, Cockrell C, Chang E, Gaskins HR, McIntosh MK.

J Nutr Biochem. 2016 Jan;27:123-35. doi: 10.1016/j.jnutbio.2015.08.027. Epub 2015 Sep 2.


Alterations of a Cellular Cholesterol Metabolism Network Are a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease.

Ding J, Reynolds LM, Zeller T, Müller C, Lohman K, Nicklas BJ, Kritchevsky SB, Huang Z, de la Fuente A, Soranzo N, Settlage RE, Chuang CC, Howard T, Xu N, Goodarzi MO, Chen YD, Rotter JI, Siscovick DS, Parks JS, Murphy S, Jacobs DR Jr, Post W, Tracy RP, Wild PS, Blankenberg S, Hoeschele I, Herrington D, McCall CE, Liu Y.

Diabetes. 2015 Oct;64(10):3464-74. doi: 10.2337/db14-1314. Epub 2015 Jul 7.


Low level of trans-10, cis-12 conjugated linoleic acid decreases adiposity and increases browning independent of inflammatory signaling in overweight Sv129 mice.

Shen W, Baldwin J, Collins B, Hixson L, Lee KT, Herberg T, Starnes J, Cooney P, Chuang CC, Hopkins R, Reid T, Gupta S, McIntosh M.

J Nutr Biochem. 2015 Jun;26(6):616-25. doi: 10.1016/j.jnutbio.2014.12.016. Epub 2015 Feb 26.


Uncleaved ApoM signal peptide is required for formation of large ApoM/sphingosine 1-phosphate (S1P)-enriched HDL particles.

Liu M, Allegood J, Zhu X, Seo J, Gebre AK, Boudyguina E, Cheng D, Chuang CC, Shelness GS, Spiegel S, Parks JS.

J Biol Chem. 2015 Mar 20;290(12):7861-70. doi: 10.1074/jbc.M114.631101. Epub 2015 Jan 27.


An abundant dysfunctional apolipoprotein A1 in human atheroma.

Huang Y, DiDonato JA, Levison BS, Schmitt D, Li L, Wu Y, Buffa J, Kim T, Gerstenecker GS, Gu X, Kadiyala CS, Wang Z, Culley MK, Hazen JE, Didonato AJ, Fu X, Berisha SZ, Peng D, Nguyen TT, Liang S, Chuang CC, Cho L, Plow EF, Fox PL, Gogonea V, Tang WH, Parks JS, Fisher EA, Smith JD, Hazen SL.

Nat Med. 2014 Feb;20(2):193-203. doi: 10.1038/nm.3459. Epub 2014 Jan 26.


Myeloid cell-specific ABCA1 deletion does not worsen insulin resistance in HF diet-induced or genetically obese mouse models.

Zhu X, Chung S, Bi X, Chuang CC, Brown AL, Liu M, Seo J, Cuffe H, Gebre AK, Boudyguina E, Parks JS.

J Lipid Res. 2013 Oct;54(10):2708-17. doi: 10.1194/jlr.M038943. Epub 2013 Jul 27.


The phospholipase C inhibitor U73122 attenuates trans-10, cis-12 conjugated linoleic acid-mediated inflammatory signaling and insulin resistance in human adipocytes.

Shen W, Martinez K, Chuang CC, McIntosh M.

J Nutr. 2013 May;143(5):584-90. doi: 10.3945/jn.112.173161. Epub 2013 Mar 6.


Conjugated linoleic acid reduces adiposity and increases markers of browning and inflammation in white adipose tissue of mice.

Shen W, Chuang CC, Martinez K, Reid T, Brown JM, Xi L, Hixson L, Hopkins R, Starnes J, McIntosh M.

J Lipid Res. 2013 Apr;54(4):909-22. doi: 10.1194/jlr.M030924. Epub 2013 Feb 11.


Diacylglycerol kinase inhibitor R59022 attenuates conjugated linoleic acid-mediated inflammation in human adipocytes.

Martinez K, Shyamasundar S, Kennedy A, Chuang CC, Marsh A, Kincaid J, Reid T, McIntosh M.

J Lipid Res. 2013 Mar;54(3):662-70. doi: 10.1194/jlr.M031211. Epub 2012 Dec 22.


Differential effects of grape powder and its extract on glucose tolerance and chronic inflammation in high-fat-fed obese mice.

Chuang CC, Shen W, Chen H, Xie G, Jia W, Chung S, McIntosh MK.

J Agric Food Chem. 2012 Dec 26;60(51):12458-68. doi: 10.1021/jf3028107. Epub 2012 Dec 14.


Potential mechanisms by which polyphenol-rich grapes prevent obesity-mediated inflammation and metabolic diseases.

Chuang CC, McIntosh MK.

Annu Rev Nutr. 2011 Aug 21;31:155-76. doi: 10.1146/annurev-nutr-072610-145149. Review.


Quercetin is equally or more effective than resveratrol in attenuating tumor necrosis factor-{alpha}-mediated inflammation and insulin resistance in primary human adipocytes.

Chuang CC, Martinez K, Xie G, Kennedy A, Bumrungpert A, Overman A, Jia W, McIntosh MK.

Am J Clin Nutr. 2010 Dec;92(6):1511-21. doi: 10.3945/ajcn.2010.29807. Epub 2010 Oct 13.


Grape powder extract attenuates tumor necrosis factor α-mediated inflammation and insulin resistance in primary cultures of human adipocytes.

Chuang CC, Bumrungpert A, Kennedy A, Overman A, West T, Dawson B, McIntosh MK.

J Nutr Biochem. 2011 Jan;22(1):89-94. doi: 10.1016/j.jnutbio.2009.12.002. Epub 2010 Apr 10.


Xanthones from mangosteen inhibit inflammation in human macrophages and in human adipocytes exposed to macrophage-conditioned media.

Bumrungpert A, Kalpravidh RW, Chuang CC, Overman A, Martinez K, Kennedy A, McIntosh M.

J Nutr. 2010 Apr;140(4):842-7. doi: 10.3945/jn.109.120022. Epub 2010 Feb 24.


Titanium implants alter endothelial function and vasoconstriction via a protein kinase C-regulated pathway.

Yang RS, Tzeng HP, Ho FM, Chuang CC, Chen BL, Huang CF, Chen YW, Chen RM, Liu SH.

Acta Biomater. 2009 Oct;5(8):3258-64. doi: 10.1016/j.actbio.2009.05.006. Epub 2009 May 13.


Xanthones from mangosteen prevent lipopolysaccharide-mediated inflammation and insulin resistance in primary cultures of human adipocytes.

Bumrungpert A, Kalpravidh RW, Chitchumroonchokchai C, Chuang CC, West T, Kennedy A, McIntosh M.

J Nutr. 2009 Jun;139(6):1185-91. doi: 10.3945/jn.109.106617. Epub 2009 Apr 29.


Saturated fatty acid-mediated inflammation and insulin resistance in adipose tissue: mechanisms of action and implications.

Kennedy A, Martinez K, Chuang CC, LaPoint K, McIntosh M.

J Nutr. 2009 Jan;139(1):1-4. doi: 10.3945/jn.108.098269. Epub 2008 Dec 3. Review.


Conjugated linoleic acid-mediated inflammation and insulin resistance in human adipocytes are attenuated by resveratrol.

Kennedy A, Overman A, Lapoint K, Hopkins R, West T, Chuang CC, Martinez K, Bell D, McIntosh M.

J Lipid Res. 2009 Feb;50(2):225-32. doi: 10.1194/jlr.M800258-JLR200. Epub 2008 Sep 5.

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