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Items: 19


The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington's Disease.

Dong X, Tsuji J, Labadorf A, Roussos P, Chen JF, Myers RH, Akbarian S, Weng Z.

PLoS One. 2015 Dec 4;10(12):e0144398. doi: 10.1371/journal.pone.0144398.


Deciphering H3K4me3 broad domains associated with gene-regulatory networks and conserved epigenomic landscapes in the human brain.

Dincer A, Gavin DP, Xu K, Zhang B, Dudley JT, Schadt EE, Akbarian S.

Transl Psychiatry. 2015 Nov 17;5:e679. doi: 10.1038/tp.2015.169.


The role of H3K4me3 and H3K9/14ac in the induction by dexamethasone of Per1 and Sgk1, two glucococorticoid early response genes that mediate the effects of acute stress in mammals.

Xydous M, Prombona A, Sourlingas TG.

Biochim Biophys Acta. 2014 Sep;1839(9):866-72. doi: 10.1016/j.bbagrm.2014.07.011.


Epigenetic regulations of immediate early genes expression involved in memory formation by the amyloid precursor protein of Alzheimer disease.

Hendrickx A, Pierrot N, Tasiaux B, Schakman O, Kienlen-Campard P, De Smet C, Octave JN.

PLoS One. 2014 Jun 11;9(6):e99467. doi: 10.1371/journal.pone.0099467.


Epigenetic regulation of memory by acetylation and methylation of chromatin: implications in neurological disorders, aging, and addiction.

Sen N.

Neuromolecular Med. 2015 Jun;17(2):97-110. doi: 10.1007/s12017-014-8306-x. Review.


A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related tests.

Schroeder FA, Lewis MC, Fass DM, Wagner FF, Zhang YL, Hennig KM, Gale J, Zhao WN, Reis S, Barker DD, Berry-Scott E, Kim SW, Clore EL, Hooker JM, Holson EB, Haggarty SJ, Petryshen TL.

PLoS One. 2013 Aug 14;8(8):e71323. doi: 10.1371/journal.pone.0071323.


The genome in three dimensions: a new frontier in human brain research.

Mitchell AC, Bharadwaj R, Whittle C, Krueger W, Mirnics K, Hurd Y, Rasmussen T, Akbarian S.

Biol Psychiatry. 2014 Jun 15;75(12):961-9. doi: 10.1016/j.biopsych.2013.07.015. Review.


The epigenetic effect of nicotine on dopamine D1 receptor expression in rat prefrontal cortex.

Gozen O, Balkan B, Yildirim E, Koylu EO, Pogun S.

Synapse. 2013 Sep;67(9):545-52. doi: 10.1002/syn.21659.


Human-specific histone methylation signatures at transcription start sites in prefrontal neurons.

Shulha HP, Crisci JL, Reshetov D, Tushir JS, Cheung I, Bharadwaj R, Chou HJ, Houston IB, Peter CJ, Mitchell AC, Yao WD, Myers RH, Chen JF, Preuss TM, Rogaev EI, Jensen JD, Weng Z, Akbarian S.

PLoS Biol. 2012;10(11):e1001427. doi: 10.1371/journal.pbio.1001427.


Stress-associated H3K4 methylation accumulates during postnatal development and aging of rhesus macaque brain.

Han Y, Han D, Yan Z, Boyd-Kirkup JD, Green CD, Khaitovich P, Han JD.

Aging Cell. 2012 Dec;11(6):1055-64. doi: 10.1111/acel.12007.


HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity.

Kurita M, Holloway T, García-Bea A, Kozlenkov A, Friedman AK, Moreno JL, Heshmati M, Golden SA, Kennedy PJ, Takahashi N, Dietz DM, Mocci G, Gabilondo AM, Hanks J, Umali A, Callado LF, Gallitano AL, Neve RL, Shen L, Buxbaum JD, Han MH, Nestler EJ, Meana JJ, Russo SJ, González-Maeso J.

Nat Neurosci. 2012 Sep;15(9):1245-54. doi: 10.1038/nn.3181.


Epigenetic signatures of autism: trimethylated H3K4 landscapes in prefrontal neurons.

Shulha HP, Cheung I, Whittle C, Wang J, Virgil D, Lin CL, Guo Y, Lessard A, Akbarian S, Weng Z.

Arch Gen Psychiatry. 2012 Mar;69(3):314-24. doi: 10.1001/archgenpsychiatry.2011.151.


Effects of histone modifications on increased expression of polyamine biosynthetic genes in suicide.

Fiori LM, Gross JA, Turecki G.

Int J Neuropsychopharmacol. 2012 Sep;15(8):1161-6. doi: 10.1017/S1461145711001520.


Developmental regulation and individual differences of neuronal H3K4me3 epigenomes in the prefrontal cortex.

Cheung I, Shulha HP, Jiang Y, Matevossian A, Wang J, Weng Z, Akbarian S.

Proc Natl Acad Sci U S A. 2010 May 11;107(19):8824-9. doi: 10.1073/pnas.1001702107.


Genetic and epigenetic influences on expression of spermine synthase and spermine oxidase in suicide completers.

Fiori LM, Turecki G.

Int J Neuropsychopharmacol. 2010 Jul;13(6):725-36. doi: 10.1017/S1461145709991167.


Prefrontal dysfunction in schizophrenia involves mixed-lineage leukemia 1-regulated histone methylation at GABAergic gene promoters.

Huang HS, Matevossian A, Whittle C, Kim SY, Schumacher A, Baker SP, Akbarian S.

J Neurosci. 2007 Oct 17;27(42):11254-62.

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