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Items: 1 to 20 of 33


High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents (HPHC).

Marescotti D, Gonzalez Suarez I, Acali S, Johne S, Laurent A, Frentzel S, Hoeng J, Peitsch MC.

J Vis Exp. 2016 May 10;(111). doi: 10.3791/53987.


Systems pharmacology-based approach for dissecting the active ingredients and potential targets of the Chinese herbal Bufei Jianpi formula for the treatment of COPD.

Zhao P, Li J, Li Y, Tian Y, Wang Y, Zheng C.

Int J Chron Obstruct Pulmon Dis. 2015 Dec 7;10:2633-56. doi: 10.2147/COPD.S94043. eCollection 2015.


Endothelial disruptive proinflammatory effects of nicotine and e-cigarette vapor exposures.

Schweitzer KS, Chen SX, Law S, Van Demark M, Poirier C, Justice MJ, Hubbard WC, Kim ES, Lai X, Wang M, Kranz WD, Carroll CJ, Ray BD, Bittman R, Goodpaster J, Petrache I.

Am J Physiol Lung Cell Mol Physiol. 2015 Jul 15;309(2):L175-87. doi: 10.1152/ajplung.00411.2014. Epub 2015 May 15.


Expression variations of connective tissue growth factor in pulmonary arteries from smokers with and without chronic obstructive pulmonary disease.

Zhou SJ, Li M, Zeng DX, Zhu ZM, Hu XW, Li YH, Wang R, Sun GY.

Sci Rep. 2015 Feb 24;5:8564. doi: 10.1038/srep08564.


Simvastatin mitigates functional and structural impairment of lung and right ventricle in a rat model of cigarette smoke-induced COPD.

Wang Y, Jiang X, Zhang L, Wang L, Li Z, Sun W.

Int J Clin Exp Pathol. 2014 Dec 1;7(12):8553-62. eCollection 2014.


Effects of exercise training on pulmonary vessel muscularization and right ventricular function in an animal model of COPD.

Hassel E, Berre AM, Skjulsvik AJ, Steinshamn S.

Respir Res. 2014 Sep 28;15:117. doi: 10.1186/s12931-014-0117-y.


Circulating progenitor cells and vascular dysfunction in chronic obstructive pulmonary disease.

Pizarro S, García-Lucio J, Peinado VI, Tura-Ceide O, Díez M, Blanco I, Sitges M, Petriz J, Torralba Y, Marín P, Roca J, Barberà JA.

PLoS One. 2014 Aug 29;9(8):e106163. doi: 10.1371/journal.pone.0106163. eCollection 2014. Erratum in: PLoS One. 2014;9(12):e115566.


β2-Adrenoceptor involved in smoking-induced airway mucus hypersecretion through β-arrestin-dependent signaling.

Zhou Y, Zhang Y, Guo Y, Zhang Y, Xu M, He B.

PLoS One. 2014 Jun 6;9(6):e97788. doi: 10.1371/journal.pone.0097788. eCollection 2014.


An aberrant leukotriene A4 hydrolase-proline-glycine-proline pathway in the pathogenesis of chronic obstructive pulmonary disease.

Wells JM, O'Reilly PJ, Szul T, Sullivan DI, Handley G, Garrett C, McNicholas CM, Roda MA, Miller BE, Tal-Singer R, Gaggar A, Rennard SI, Jackson PL, Blalock JE.

Am J Respir Crit Care Med. 2014 Jul 1;190(1):51-61. doi: 10.1164/rccm.201401-0145OC.


Effects of chronic exposure to cigarette smoke on canonical transient receptor potential expression in rat pulmonary arterial smooth muscle.

Wang J, Chen Y, Lin C, Jia J, Tian L, Yang K, Zhao L, Lai N, Jiang Q, Sun Y, Zhong N, Ran P, Lu W.

Am J Physiol Cell Physiol. 2014 Feb 15;306(4):C364-73. doi: 10.1152/ajpcell.00048.2013. Epub 2013 Dec 11.


HIV envelope protein gp120-induced apoptosis in lung microvascular endothelial cells by concerted upregulation of EMAP II and its receptor, CXCR3.

Green LA, Yi R, Petrusca D, Wang T, Elghouche A, Gupta SK, Petrache I, Clauss M.

Am J Physiol Lung Cell Mol Physiol. 2014 Feb 15;306(4):L372-82. doi: 10.1152/ajplung.00193.2013. Epub 2013 Dec 6.


Potential mechanisms linking atherosclerosis and increased cardiovascular risk in COPD: focus on Sirtuins.

Corbi G, Bianco A, Turchiarelli V, Cellurale M, Fatica F, Daniele A, Mazzarella G, Ferrara N.

Int J Mol Sci. 2013 Jun 17;14(6):12696-713. doi: 10.3390/ijms140612696. Review.


Genomic impact of cigarette smoke, with application to three smoking-related diseases.

Talikka M, Sierro N, Ivanov NV, Chaudhary N, Peck MJ, Hoeng J, Coggins CR, Peitsch MC.

Crit Rev Toxicol. 2012 Nov;42(10):877-89. doi: 10.3109/10408444.2012.725244. Epub 2012 Sep 18. Review.


Contribution of the environment and comorbidities to chronic obstructive pulmonary disease phenotypes.

Martinez CH, Han MK.

Med Clin North Am. 2012 Jul;96(4):713-27. doi: 10.1016/j.mcna.2012.02.007. Epub 2012 Mar 22. Review.


Inflammatory transcriptome profiling of human monocytes exposed acutely to cigarette smoke.

Wright WR, Parzych K, Crawford D, Mein C, Mitchell JA, Paul-Clark MJ.

PLoS One. 2012;7(2):e30120. doi: 10.1371/journal.pone.0030120. Epub 2012 Feb 17.


Stress responses affecting homeostasis of the alveolar capillary unit.

Tuder RM, Yoshida T.

Proc Am Thorac Soc. 2011 Nov;8(6):485-91. doi: 10.1513/pats.201103-029MW. Review.


A computable cellular stress network model for non-diseased pulmonary and cardiovascular tissue.

Schlage WK, Westra JW, Gebel S, Catlett NL, Mathis C, Frushour BP, Hengstermann A, Van Hooser A, Poussin C, Wong B, Lietz M, Park J, Drubin D, Veljkovic E, Peitsch MC, Hoeng J, Deehan R.

BMC Syst Biol. 2011 Oct 19;5:168. doi: 10.1186/1752-0509-5-168.


Circulating endothelial microparticles as a measure of early lung destruction in cigarette smokers.

Gordon C, Gudi K, Krause A, Sackrowitz R, Harvey BG, Strulovici-Barel Y, Mezey JG, Crystal RG.

Am J Respir Crit Care Med. 2011 Jul 15;184(2):224-32. doi: 10.1164/rccm.201012-2061OC. Epub 2011 Mar 11.


Chronic cigarette smoking causes hypertension, increased oxidative stress, impaired NO bioavailability, endothelial dysfunction, and cardiac remodeling in mice.

Talukder MA, Johnson WM, Varadharaj S, Lian J, Kearns PN, El-Mahdy MA, Liu X, Zweier JL.

Am J Physiol Heart Circ Physiol. 2011 Jan;300(1):H388-96. doi: 10.1152/ajpheart.00868.2010. Epub 2010 Nov 5.

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