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Items: 1 to 20 of 56

1.

Crystal structure of cis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis.

Chen F, Lukat P, Iqbal AA, Saile K, Kaever V, van den Heuvel J, Blankenfeldt W, Büssow K, Pessler F.

Proc Natl Acad Sci U S A. 2019 Oct 8;116(41):20644-20654. doi: 10.1073/pnas.1908770116. Epub 2019 Sep 23.

2.

ER intrabody-mediated inhibition of interferon α secretion by mouse macrophages and dendritic cells.

Büssow K, Themann P, Luu S, Pentrowski P, Harting C, Majewski M, Vollmer V, Köster M, Grashoff M, Zawatzky R, Van den Heuvel J, Kröger A, Böldicke T.

PLoS One. 2019 Apr 16;14(4):e0215062. doi: 10.1371/journal.pone.0215062. eCollection 2019.

3.

Investigations on the mode of action of gephyronic acid, an inhibitor of eukaryotic protein translation from myxobacteria.

Muthukumar Y, Münkemer J, Mathieu D, Richter C, Schwalbe H, Steinmetz H, Kessler W, Reichelt J, Beutling U, Frank R, Büssow K, van den Heuvel J, Brönstrup M, Taylor RE, Laschat S, Sasse F.

PLoS One. 2018 Jul 31;13(7):e0201605. doi: 10.1371/journal.pone.0201605. eCollection 2018.

4.

A method for specifically targeting two independent genomic integration sites for co-expression of genes in CHO cells.

Baser B, Spehr J, Büssow K, van den Heuvel J.

Methods. 2016 Feb 15;95:3-12. doi: 10.1016/j.ymeth.2015.11.022. Epub 2015 Dec 2.

5.

Stable mammalian producer cell lines for structural biology.

Büssow K.

Curr Opin Struct Biol. 2015 Jun;32:81-90. doi: 10.1016/j.sbi.2015.03.002. Epub 2015 Mar 23. Review.

6.

High level transient production of recombinant antibodies and antibody fusion proteins in HEK293 cells.

Jäger V, Büssow K, Wagner A, Weber S, Hust M, Frenzel A, Schirrmann T.

BMC Biotechnol. 2013 Jun 26;13:52. doi: 10.1186/1472-6750-13-52.

7.

Structural characterization of amorfrutins bound to the peroxisome proliferator-activated receptor γ.

de Groot JC, Weidner C, Krausze J, Kawamoto K, Schroeder FC, Sauer S, Büssow K.

J Med Chem. 2013 Feb 28;56(4):1535-43. doi: 10.1021/jm3013272. Epub 2013 Feb 6.

8.
9.

Amorfrutins are potent antidiabetic dietary natural products.

Weidner C, de Groot JC, Prasad A, Freiwald A, Quedenau C, Kliem M, Witzke A, Kodelja V, Han CT, Giegold S, Baumann M, Klebl B, Siems K, Müller-Kuhrt L, Schürmann A, Schüler R, Pfeiffer AF, Schroeder FC, Büssow K, Sauer S.

Proc Natl Acad Sci U S A. 2012 May 8;109(19):7257-62. doi: 10.1073/pnas.1116971109. Epub 2012 Apr 16.

10.

Streamlining homogeneous glycoprotein production for biophysical and structural applications by targeted cell line development.

Wilke S, Groebe L, Maffenbeier V, Jäger V, Gossen M, Josewski J, Duda A, Polle L, Owens RJ, Wirth D, Heinz DW, van den Heuvel J, Büssow K.

PLoS One. 2011;6(12):e27829. doi: 10.1371/journal.pone.0027829. Epub 2011 Dec 9.

11.

Impaired peripheral Th1 CD4+ T cell response to Escherichia coli proteins in patients with Crohn's disease and ankylosing spondylitis.

Ergin A, Syrbe U, Scheer R, Thiel A, Adam T, Büssow K, Duchmann R, Zeitz M, Sieper J.

J Clin Immunol. 2011 Dec;31(6):998-1009. doi: 10.1007/s10875-011-9575-x. Epub 2011 Sep 8.

PMID:
21901394
12.

Structural basis for complex formation between human IRSp53 and the translocated intimin receptor Tir of enterohemorrhagic E. coli.

de Groot JC, Schlüter K, Carius Y, Quedenau C, Vingadassalom D, Faix J, Weiss SM, Reichelt J, Standfuss-Gabisch C, Lesser CF, Leong JM, Heinz DW, Büssow K, Stradal TE.

Structure. 2011 Sep 7;19(9):1294-306. doi: 10.1016/j.str.2011.06.015.

13.

Expression of protein complexes using multiple Escherichia coli protein co-expression systems: a benchmarking study.

Busso D, Peleg Y, Heidebrecht T, Romier C, Jacobovitch Y, Dantes A, Salim L, Troesch E, Schuetz A, Heinemann U, Folkers GE, Geerlof A, Wilmanns M, Polewacz A, Quedenau C, Büssow K, Adamson R, Blagova E, Walton J, Cartwright JL, Bird LE, Owens RJ, Berrow NS, Wilson KS, Sussman JL, Perrakis A, Celie PH.

J Struct Biol. 2011 Aug;175(2):159-70. doi: 10.1016/j.jsb.2011.03.004. Epub 2011 Mar 5.

PMID:
21382497
14.

Glycoprotein production for structure analysis with stable, glycosylation mutant CHO cell lines established by fluorescence-activated cell sorting.

Wilke S, Krausze J, Gossen M, Groebe L, Jäger V, Gherardi E, van den Heuvel J, Büssow K.

Protein Sci. 2010 Jun;19(6):1264-71. doi: 10.1002/pro.390.

15.

Identification of the predominant antigenic epitopes in intestinal flora in IBD.

Ergin A, Adam T, Büssow K, Thiel A, Sieper J, Duchmann R.

Mucosal Immunol. 2008 Nov;1 Suppl 1:S19-23. doi: 10.1038/mi.2008.44.

PMID:
19079222
16.

Structural and functional characterization of human Iba proteins.

Schulze JO, Quedenau C, Roske Y, Adam T, Schüler H, Behlke J, Turnbull AP, Sievert V, Scheich C, Mueller U, Heinemann U, Büssow K.

FEBS J. 2008 Sep;275(18):4627-40. doi: 10.1111/j.1742-4658.2008.06605.x. Epub 2008 Aug 11.

17.

High throughput cloning with restriction enzymes.

Sievert V, Ergin A, Büssow K.

Methods Mol Biol. 2008;426:163-73. doi: 10.1007/978-1-60327-058-8_9.

PMID:
18542862
18.

Protein production and purification.

Structural Genomics Consortium; China Structural Genomics Consortium; Northeast Structural Genomics Consortium, Gräslund S, Nordlund P, Weigelt J, Hallberg BM, Bray J, Gileadi O, Knapp S, Oppermann U, Arrowsmith C, Hui R, Ming J, dhe-Paganon S, Park HW, Savchenko A, Yee A, Edwards A, Vincentelli R, Cambillau C, Kim R, Kim SH, Rao Z, Shi Y, Terwilliger TC, Kim CY, Hung LW, Waldo GS, Peleg Y, Albeck S, Unger T, Dym O, Prilusky J, Sussman JL, Stevens RC, Lesley SA, Wilson IA, Joachimiak A, Collart F, Dementieva I, Donnelly MI, Eschenfeldt WH, Kim Y, Stols L, Wu R, Zhou M, Burley SK, Emtage JS, Sauder JM, Thompson D, Bain K, Luz J, Gheyi T, Zhang F, Atwell S, Almo SC, Bonanno JB, Fiser A, Swaminathan S, Studier FW, Chance MR, Sali A, Acton TB, Xiao R, Zhao L, Ma LC, Hunt JF, Tong L, Cunningham K, Inouye M, Anderson S, Janjua H, Shastry R, Ho CK, Wang D, Wang H, Jiang M, Montelione GT, Stuart DI, Owens RJ, Daenke S, Schütz A, Heinemann U, Yokoyama S, Büssow K, Gunsalus KC.

Nat Methods. 2008 Feb;5(2):135-46. doi: 10.1038/nmeth.f.202. Review. Erratum in: Nat Methods. 2008 Apr;5(4):369. Hallberg, B Martin [added].

19.

Automated technologies and novel techniques to accelerate protein crystallography for structural genomics.

Manjasetty BA, Turnbull AP, Panjikar S, Büssow K, Chance MR.

Proteomics. 2008 Feb;8(4):612-25. doi: 10.1002/pmic.200700687. Review.

PMID:
18210369
20.

Homologous high-throughput expression and purification of highly conserved E coli proteins.

Ergin A, Büssow K, Sieper J, Thiel A, Duchmann R, Adam T.

Microb Cell Fact. 2007 Jun 6;6:18.

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