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Oligomerization Alters Binding Affinity Between Amyloid Beta and a Modulator of Peptide Aggregation.

Hilt S, Rojalin T, Viitala T, Koivuniemi A, Bunker A, Hogiu SW, Kálai T, Hideg K, Yliperttula M, Voss JC.

J Phys Chem C Nanomater Interfaces. 2017 Nov 2;121(43):23974-23987. doi: 10.1021/acs.jpcc.7b06164. Epub 2017 Oct 10.


Lipid Architectonics for Superior Oral Bioavailability of Nelfinavir Mesylate: Comparative in vitro and in vivo Assessment.

Belubbi T, Shevade S, Dhawan V, Sridhar V, Majumdar A, Nunes R, Araújo F, Sarmento B, Nagarsenker K, Steiniger F, Fahr A, Magarkar A, Bunker A, Nagarsenker M.

AAPS PharmSciTech. 2018 Nov;19(8):3584-3598. doi: 10.1208/s12249-018-1156-3. Epub 2018 Sep 12.


Control of Peptide Aggregation and Fibrillation by Physical PEGylation.

Ambrosio E, Podmore A, Gomes Dos Santos AL, Magarkar A, Bunker A, Caliceti P, Mastrotto F, van der Walle CF, Salmaso S.

Biomacromolecules. 2018 Oct 8;19(10):3958-3969. doi: 10.1021/acs.biomac.8b00887. Epub 2018 Sep 4.


The effect of light sensitizer localization on the stability of indocyanine green liposomes.

Lajunen T, Nurmi R, Wilbie D, Ruoslahti T, Johansson NG, Korhonen O, Rog T, Bunker A, Ruponen M, Urtti A.

J Control Release. 2018 Aug 28;284:213-223. doi: 10.1016/j.jconrel.2018.06.029. Epub 2018 Jun 28.


Biophysical Characterization of Supported Lipid Bilayers Using Parallel Dual-Wavelength Surface Plasmon Resonance and Quartz Crystal Microbalance Measurements.

Parkkila P, Elderdfi M, Bunker A, Viitala T.

Langmuir. 2018 Jul 10;34(27):8081-8091. doi: 10.1021/acs.langmuir.8b01259. Epub 2018 Jun 25.


Comparison of time-gated surface-enhanced raman spectroscopy (TG-SERS) and classical SERS based monitoring of Escherichia coli cultivation samples.

Kögler M, Paul A, Anane E, Birkholz M, Bunker A, Viitala T, Maiwald M, Junne S, Neubauer P.

Biotechnol Prog. 2018 Nov;34(6):1533-1542. doi: 10.1002/btpr.2665. Epub 2018 Aug 6.


Membrane bound COMT isoform is an interfacial enzyme: general mechanism and new drug design paradigm.

Magarkar A, Parkkila P, Viitala T, Lajunen T, Mobarak E, Licari G, Cramariuc O, Vauthey E, Róg T, Bunker A.

Chem Commun (Camb). 2018 Apr 3;54(28):3440-3443. doi: 10.1039/c8cc00221e.


Estimated Effect of Temperature on Years of Life Lost: A Retrospective Time-Series Study of Low-, Middle-, and High-Income Regions.

Odhiambo Sewe M, Bunker A, Ingole V, Egondi T, Oudin Åström D, Hondula DM, Rocklöv J, Schumann B.

Environ Health Perspect. 2018 Jan 12;126(1):017004. doi: 10.1289/EHP1745.


Excess burden of non-communicable disease years of life lost from heat in rural Burkina Faso: a time series analysis of the years 2000-2010.

Bunker A, Sewe MO, Sié A, Rocklöv J, Sauerborn R.

BMJ Open. 2017 Nov 4;7(11):e018068. doi: 10.1136/bmjopen-2017-018068.


Interactions between Chloramphenicol, Carrier Polymers, and Bacteria-Implications for Designing Electrospun Drug Delivery Systems Countering Wound Infection.

Preem L, Mahmoudzadeh M, Putrinš M, Meos A, Laidmäe I, Romann T, Aruväli J, Härmas R, Koivuniemi A, Bunker A, Tenson T, Kogermann K.

Mol Pharm. 2017 Dec 4;14(12):4417-4430. doi: 10.1021/acs.molpharmaceut.7b00524. Epub 2017 Nov 16.


A novel in silico framework to improve MHC-I epitopes and break the tolerance to melanoma.

Capasso C, Magarkar A, Cervera-Carascon V, Fusciello M, Feola S, Muller M, Garofalo M, Kuryk L, Tähtinen S, Pastore L, Bunker A, Cerullo V.

Oncoimmunology. 2017 May 11;6(9):e1319028. doi: 10.1080/2162402X.2017.1319028. eCollection 2017. Erratum in: Oncoimmunology. 2017 Oct 6;6(10 ):e1389146.


Adaptation to Climate Change: A Comparative Analysis of Modeling Methods for Heat-Related Mortality.

Gosling SN, Hondula DM, Bunker A, Ibarreta D, Liu J, Zhang X, Sauerborn R.

Environ Health Perspect. 2017 Aug 16;125(8):087008. doi: 10.1289/EHP634.


Influence of doxorubicin on model cell membrane properties: insights from in vitro and in silico studies.

Alves AC, Magarkar A, Horta M, Lima JLFC, Bunker A, Nunes C, Reis S.

Sci Rep. 2017 Jul 24;7(1):6343. doi: 10.1038/s41598-017-06445-z.


A computational study suggests that replacing PEG with PMOZ may increase exposure of hydrophobic targeting moiety.

Magarkar A, Róg T, Bunker A.

Eur J Pharm Sci. 2017 May 30;103:128-135. doi: 10.1016/j.ejps.2017.03.008. Epub 2017 Mar 9.


Effects of Membrane PEGylation on Entry and Location of Antifungal Drug Itraconazole and Their Pharmacological Implications.

Dzieciuch-Rojek M, Poojari C, Bednar J, Bunker A, Kozik B, Nowakowska M, Vattulainen I, Wydro P, Kepczynski M, Róg T.

Mol Pharm. 2017 Apr 3;14(4):1057-1070. doi: 10.1021/acs.molpharmaceut.6b00969. Epub 2017 Mar 7.


Effect of piroxicam on lipid membranes: Drug encapsulation and gastric toxicity aspects.

Wilkosz N, Rissanen S, Cyza M, Szybka R, Nowakowska M, Bunker A, Róg T, Kepczynski M.

Eur J Pharm Sci. 2017 Mar 30;100:116-125. doi: 10.1016/j.ejps.2017.01.007. Epub 2017 Jan 10.


Design of cholesterol arabinogalactan anchored liposomes for asialoglycoprotein receptor mediated targeting to hepatocellular carcinoma: In silico modeling, in vitro and in vivo evaluation.

Pathak P, Dhawan V, Magarkar A, Danne R, Govindarajan S, Ghosh S, Steiniger F, Chaudhari P, Gopal V, Bunker A, Róg T, Fahr A, Nagarsenker M.

Int J Pharm. 2016 Jul 25;509(1-2):149-158. doi: 10.1016/j.ijpharm.2016.05.041. Epub 2016 May 23.


Effects of Air Temperature on Climate-Sensitive Mortality and Morbidity Outcomes in the Elderly; a Systematic Review and Meta-analysis of Epidemiological Evidence.

Bunker A, Wildenhain J, Vandenbergh A, Henschke N, Rocklöv J, Hajat S, Sauerborn R.

EBioMedicine. 2016 Apr;6:258-268. doi: 10.1016/j.ebiom.2016.02.034. Epub 2016 Feb 23. Review.


Oncolytic adenoviruses coated with MHC-I tumor epitopes increase the antitumor immunity and efficacy against melanoma.

Capasso C, Hirvinen M, Garofalo M, Romaniuk D, Kuryk L, Sarvela T, Vitale A, Antopolsky M, Magarkar A, Viitala T, Suutari T, Bunker A, Yliperttula M, Urtti A, Cerullo V.

Oncoimmunology. 2015 Oct 29;5(4):e1105429. eCollection 2016 Apr.


Indocyanine Green-Loaded Liposomes for Light-Triggered Drug Release.

Lajunen T, Kontturi LS, Viitala L, Manna M, Cramariuc O, Róg T, Bunker A, Laaksonen T, Viitala T, Murtomäki L, Urtti A.

Mol Pharm. 2016 Jun 6;13(6):2095-107. doi: 10.1021/acs.molpharmaceut.6b00207. Epub 2016 Apr 29.


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