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Items: 1 to 20 of 119

1.

The naked mole-rat exhibits an unusual cardiac myofilament protein profile providing new insights into heart function of this naturally subterranean rodent.

Grimes KM, Barefield DY, Kumar M, McNamara JW, Weintraub ST, de Tombe PP, Sadayappan S, Buffenstein R.

Pflugers Arch. 2017 Aug 5. doi: 10.1007/s00424-017-2046-3. [Epub ahead of print]

PMID:
28780592
2.

Extended Postnatal Brain Development in the Longest-Lived Rodent: Prolonged Maintenance of Neotenous Traits in the Naked Mole-Rat Brain.

Orr ME, Garbarino VR, Salinas A, Buffenstein R.

Front Neurosci. 2016 Nov 8;10:504. eCollection 2016.

3.

Cutting back on the essentials: Can manipulating intake of specific amino acids modulate health and lifespan?

Brown-Borg HM, Buffenstein R.

Ageing Res Rev. 2017 Oct;39:87-95. doi: 10.1016/j.arr.2016.08.007. Epub 2016 Aug 26. Review.

PMID:
27570078
4.

Unraveling the message: insights into comparative genomics of the naked mole-rat.

Lewis KN, Soifer I, Melamud E, Roy M, McIsaac RS, Hibbs M, Buffenstein R.

Mamm Genome. 2016 Aug;27(7-8):259-78. doi: 10.1007/s00335-016-9648-5. Epub 2016 Jun 30. Review.

5.

Mechanisms regulating proteostasis are involved in sympatric speciation of the blind mole rat, Spalax galili.

Rodriguez KA, Li K, Nevo E, Buffenstein R.

Autophagy. 2016;12(4):703-4. doi: 10.1080/15548627.2016.1143592.

6.

From yeast to human: exploring the comparative biology of methionine restriction in extending eukaryotic life span.

McIsaac RS, Lewis KN, Gibney PA, Buffenstein R.

Ann N Y Acad Sci. 2016 Jan;1363:155-70. doi: 10.1111/nyas.13032. Review.

PMID:
26995762
7.

Reaching Out to Send a Message: Proteins Associated with Neurite Outgrowth and Neurotransmission are Altered with Age in the Long-Lived Naked Mole-Rat.

Triplett JC, Swomley AM, Kirk J, Grimes KM, Lewis KN, Orr ME, Rodriguez KA, Cai J, Klein JB, Buffenstein R, Butterfield DA.

Neurochem Res. 2016 Jul;41(7):1625-34. doi: 10.1007/s11064-016-1877-1. Epub 2016 Mar 2.

PMID:
26935741
8.

Determinants of rodent longevity in the chaperone-protein degradation network.

Rodriguez KA, Valentine JM, Kramer DA, Gelfond JA, Kristan DM, Nevo E, Buffenstein R.

Cell Stress Chaperones. 2016 May;21(3):453-66. doi: 10.1007/s12192-016-0672-x. Epub 2016 Feb 19.

9.

Oxidative stress and life histories: unresolved issues and current needs.

Speakman JR, Blount JD, Bronikowski AM, Buffenstein R, Isaksson C, Kirkwood TB, Monaghan P, Ozanne SE, Beaulieu M, Briga M, Carr SK, Christensen LL, Cochemé HM, Cram DL, Dantzer B, Harper JM, Jurk D, King A, Noguera JC, Salin K, Sild E, Simons MJ, Smith S, Stier A, Tobler M, Vitikainen E, Peaker M, Selman C.

Ecol Evol. 2015 Nov 17;5(24):5745-57. doi: 10.1002/ece3.1790. eCollection 2015 Dec.

10.

Homology cluster differential expression analysis for interspecies mRNA-Seq experiments.

Gelfond JA, Ibrahim JG, Chen MH, Sun W, Lewis K, Kinahan S, Hibbs M, Buffenstein R.

Stat Appl Genet Mol Biol. 2015 Dec;14(6):507-16. doi: 10.1515/sagmb-2014-0056.

PMID:
26595407
11.

Organization of the Mammalian Ionome According to Organ Origin, Lineage Specialization, and Longevity.

Ma S, Lee SG, Kim EB, Park TJ, Seluanov A, Gorbunova V, Buffenstein R, Seravalli J, Gladyshev VN.

Cell Rep. 2015 Nov 17;13(7):1319-1326. doi: 10.1016/j.celrep.2015.10.014. Epub 2015 Nov 5.

12.

Multifactorial processes to slowing the biological clock: Insights from a comparative approach.

Sanchez JR, Milton SL, Corbit KC, Buffenstein R.

Exp Gerontol. 2015 Nov;71:27-37. doi: 10.1016/j.exger.2015.08.017. Epub 2015 Sep 4. Review.

PMID:
26343258
13.

Sympatric speciation revealed by genome-wide divergence in the blind mole rat Spalax.

Li K, Hong W, Jiao H, Wang GD, Rodriguez KA, Buffenstein R, Zhao Y, Nevo E, Zhao H.

Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):11905-10. doi: 10.1073/pnas.1514896112. Epub 2015 Sep 4.

14.

Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity.

Triplett JC, Tramutola A, Swomley A, Kirk J, Grimes K, Lewis K, Orr M, Rodriguez K, Cai J, Klein JB, Perluigi M, Buffenstein R, Butterfield DA.

Biochim Biophys Acta. 2015 Oct;1852(10 Pt A):2213-24. doi: 10.1016/j.bbadis.2015.08.002. Epub 2015 Aug 4.

15.

Organization of the Mammalian Metabolome according to Organ Function, Lineage Specialization, and Longevity.

Ma S, Yim SH, Lee SG, Kim EB, Lee SR, Chang KT, Buffenstein R, Lewis KN, Park TJ, Miller RA, Clish CB, Gladyshev VN.

Cell Metab. 2015 Aug 4;22(2):332-43. doi: 10.1016/j.cmet.2015.07.005.

16.

Metabolic clues to salubrious longevity in the brain of the longest-lived rodent: the naked mole-rat.

Triplett JC, Swomley A, Kirk J, Lewis K, Orr M, Rodriguez K, Cai J, Klein JB, Buffenstein R, Butterfield DA.

J Neurochem. 2015 Aug;134(3):538-50. doi: 10.1111/jnc.13149. Epub 2015 Jun 3.

17.

Mechanisms of oxidative stress resistance in the brain: Lessons learned from hypoxia tolerant extremophilic vertebrates.

Garbarino VR, Orr ME, Rodriguez KA, Buffenstein R.

Arch Biochem Biophys. 2015 Jun 15;576:8-16. doi: 10.1016/j.abb.2015.01.029. Epub 2015 Apr 1. Review.

18.

Regulation of Nrf2 signaling and longevity in naturally long-lived rodents.

Lewis KN, Wason E, Edrey YH, Kristan DM, Nevo E, Buffenstein R.

Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3722-7. doi: 10.1073/pnas.1417566112. Epub 2015 Mar 9.

19.

Gene expression defines natural changes in mammalian lifespan.

Fushan AA, Turanov AA, Lee SG, Kim EB, Lobanov AV, Yim SH, Buffenstein R, Lee SR, Chang KT, Rhee H, Kim JS, Yang KS, Gladyshev VN.

Aging Cell. 2015 Jun;14(3):352-65. doi: 10.1111/acel.12283. Epub 2015 Feb 9. Review.

20.

Long-lived species have improved proteostasis compared to phylogenetically-related shorter-lived species.

Pride H, Yu Z, Sunchu B, Mochnick J, Coles A, Zhang Y, Buffenstein R, Hornsby PJ, Austad SN, Pérez VI.

Biochem Biophys Res Commun. 2015 Feb 20;457(4):669-75. doi: 10.1016/j.bbrc.2015.01.046. Epub 2015 Jan 21.

PMID:
25615820

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