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Items: 1 to 20 of 164

1.

A Plasmodium berghei sporozoite-based vaccination platform against human malaria.

Mendes AM, Machado M, Gonçalves-Rosa N, Reuling IJ, Foquet L, Marques C, Salman AM, Yang ASP, Moser KA, Dwivedi A, Hermsen CC, Jiménez-Díaz B, Viera S, Santos JM, Albuquerque I, Bhatia SN, Bial J, Angulo-Barturen I, Silva JC, Leroux-Roels G, Janse CJ, Khan SM, Mota MM, Sauerwein RW, Prudêncio M.

NPJ Vaccines. 2018 Aug 24;3:33. doi: 10.1038/s41541-018-0068-2. eCollection 2018.

2.

Classification of prostate cancer using a protease activity nanosensor library.

Dudani JS, Ibrahim M, Kirkpatrick J, Warren AD, Bhatia SN.

Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):8954-8959. doi: 10.1073/pnas.1805337115. Epub 2018 Aug 20.

PMID:
30126988
3.

iRGD-guided Tumor-penetrating Nanocomplexes for Therapeutic siRNA Delivery to Pancreatic Cancer.

Lo JH, Hao L, Muzumdar MD, Raghavan S, Kwon EJ, Pulver EM, Hsu F, Aguirre AJ, Wolpin BM, Fuchs CS, Hahn WC, Jacks T, Bhatia SN.

Mol Cancer Ther. 2018 Nov;17(11):2377-2388. doi: 10.1158/1535-7163.MCT-17-1090. Epub 2018 Aug 10.

PMID:
30097486
4.

Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer.

Viswanathan SR, Nogueira MF, Buss CG, Krill-Burger JM, Wawer MJ, Malolepsza E, Berger AC, Choi PS, Shih J, Taylor AM, Tanenbaum B, Pedamallu CS, Cherniack AD, Tamayo P, Strathdee CA, Lage K, Carr SA, Schenone M, Bhatia SN, Vazquez F, Tsherniak A, Hahn WC, Meyerson M.

Nat Genet. 2018 Jul;50(7):937-943. doi: 10.1038/s41588-018-0155-3. Epub 2018 Jun 28.

PMID:
29955178
5.

Phenotypic Screening of Small Molecules with Antimalarial Activity for Three Different Parasitic Life Stages.

Kato N, March S, Bhatia SN, Marti M.

Methods Mol Biol. 2018;1787:41-52. doi: 10.1007/978-1-4939-7847-2_3.

PMID:
29736708
6.

A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.

Kisalu NK, Idris AH, Weidle C, Flores-Garcia Y, Flynn BJ, Sack BK, Murphy S, Schön A, Freire E, Francica JR, Miller AB, Gregory J, March S, Liao HX, Haynes BF, Wiehe K, Trama AM, Saunders KO, Gladden MA, Monroe A, Bonsignori M, Kanekiyo M, Wheatley AK, McDermott AB, Farney SK, Chuang GY, Zhang B, Kc N, Chakravarty S, Kwong PD, Sinnis P, Bhatia SN, Kappe SHI, Sim BKL, Hoffman SL, Zavala F, Pancera M, Seder RA.

Nat Med. 2018 May;24(4):408-416. doi: 10.1038/nm.4512. Epub 2018 Mar 19.

7.

In Vitro Culture, Drug Sensitivity, and Transcriptome of Plasmodium Vivax Hypnozoites.

Gural N, Mancio-Silva L, Miller AB, Galstian A, Butty VL, Levine SS, Patrapuvich R, Desai SP, Mikolajczak SA, Kappe SHI, Fleming HE, March S, Sattabongkot J, Bhatia SN.

Cell Host Microbe. 2018 Mar 14;23(3):395-406.e4. doi: 10.1016/j.chom.2018.01.002. Epub 2018 Feb 22.

PMID:
29478773
8.

Personalized RNA Medicine for Pancreatic Cancer.

Gilles ME, Hao L, Huang L, Rupaimoole R, Lopez-Casas PP, Pulver E, Jeong JC, Muthuswamy SK, Hidalgo M, Bhatia SN, Slack FJ.

Clin Cancer Res. 2018 Apr 1;24(7):1734-1747. doi: 10.1158/1078-0432.CCR-17-2733. Epub 2018 Jan 12.

PMID:
29330203
9.

Engineered Livers for Infectious Diseases.

Gural N, Mancio-Silva L, He J, Bhatia SN.

Cell Mol Gastroenterol Hepatol. 2017 Nov 22;5(2):131-144. doi: 10.1016/j.jcmgh.2017.11.005. eCollection 2018. Review.

10.

Depolarization signatures map gold nanorods within biological tissue.

Lippok N, Villiger M, Albanese A, Meijer EFJ, Chung K, Padera TP, Bhatia SN, Bouma BE.

Nat Photonics. 2017;11:583-588. doi: 10.1038/nphoton.2017.128. Epub 2017 Jul 31.

11.

A robust cell culture system supporting the complete life cycle of hepatitis B virus.

Michailidis E, Pabon J, Xiang K, Park P, Ramanan V, Hoffmann HH, Schneider WM, Bhatia SN, de Jong YP, Shlomai A, Rice CM.

Sci Rep. 2017 Nov 30;7(1):16616. doi: 10.1038/s41598-017-16882-5.

12.

Tumor-Penetrating Delivery of siRNA against TNFα to Human Vestibular Schwannomas.

Ren Y, Sagers JE, Landegger LD, Bhatia SN, Stankovic KM.

Sci Rep. 2017 Oct 10;7(1):12922. doi: 10.1038/s41598-017-13032-9.

13.

Ultrasensitive tumour-penetrating nanosensors of protease activity.

Kwon EJ, Dudani JS, Bhatia SN.

Nat Biomed Eng. 2017;1. pii: 0054. doi: 10.1038/s41551-017-0054. Epub 2017 Apr 10.

14.

Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine.

Geller LT, Barzily-Rokni M, Danino T, Jonas OH, Shental N, Nejman D, Gavert N, Zwang Y, Cooper ZA, Shee K, Thaiss CA, Reuben A, Livny J, Avraham R, Frederick DT, Ligorio M, Chatman K, Johnston SE, Mosher CM, Brandis A, Fuks G, Gurbatri C, Gopalakrishnan V, Kim M, Hurd MW, Katz M, Fleming J, Maitra A, Smith DA, Skalak M, Bu J, Michaud M, Trauger SA, Barshack I, Golan T, Sandbank J, Flaherty KT, Mandinova A, Garrett WS, Thayer SP, Ferrone CR, Huttenhower C, Bhatia SN, Gevers D, Wargo JA, Golub TR, Straussman R.

Science. 2017 Sep 15;357(6356):1156-1160. doi: 10.1126/science.aah5043.

15.

In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease.

Stevens KR, Scull MA, Ramanan V, Fortin CL, Chaturvedi RR, Knouse KA, Xiao JW, Fung C, Mirabella T, Chen AX, McCue MG, Yang MT, Fleming HE, Chung K, de Jong YP, Chen CS, Rice CM, Bhatia SN.

Sci Transl Med. 2017 Jul 19;9(399). pii: eaah5505. doi: 10.1126/scitranslmed.aah5505.

16.

Porous Silicon Nanoparticle Delivery of Tandem Peptide Anti-Infectives for the Treatment of Pseudomonas aeruginosa Lung Infections.

Kwon EJ, Skalak M, Bertucci A, Braun G, Ricci F, Ruoslahti E, Sailor MJ, Bhatia SN.

Adv Mater. 2017 Sep;29(35). doi: 10.1002/adma.201701527. Epub 2017 Jul 12.

17.

Towards a Humanized Mouse Model of Liver Stage Malaria Using Ectopic Artificial Livers.

Ng S, March S, Galstian A, Gural N, Stevens KR, Mota MM, Bhatia SN.

Sci Rep. 2017 Mar 31;7:45424. doi: 10.1038/srep45424.

18.

Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.

Kato N, Comer E, Sakata-Kato T, Sharma A, Sharma M, Maetani M, Bastien J, Brancucci NM, Bittker JA, Corey V, Clarke D, Derbyshire ER, Dornan GL, Duffy S, Eckley S, Itoe MA, Koolen KM, Lewis TA, Lui PS, Lukens AK, Lund E, March S, Meibalan E, Meier BC, McPhail JA, Mitasev B, Moss EL, Sayes M, Van Gessel Y, Wawer MJ, Yoshinaga T, Zeeman AM, Avery VM, Bhatia SN, Burke JE, Catteruccia F, Clardy JC, Clemons PA, Dechering KJ, Duvall JR, Foley MA, Gusovsky F, Kocken CH, Marti M, Morningstar ML, Munoz B, Neafsey DE, Sharma A, Winzeler EA, Wirth DF, Scherer CA, Schreiber SL.

Nature. 2016 Oct 20;538(7625):344-349. doi: 10.1038/nature19804. Epub 2016 Sep 7.

19.

High-Throughput Platform for Identifying Molecular Factors Involved in Phenotypic Stabilization of Primary Human Hepatocytes In Vitro.

Shan J, Logan DJ, Root DE, Carpenter AE, Bhatia SN.

J Biomol Screen. 2016 Oct;21(9):897-911. doi: 10.1177/1087057116660277. Epub 2016 Aug 4.

PMID:
27650791
20.

Magnetically Actuated Protease Sensors for in Vivo Tumor Profiling.

Schuerle S, Dudani JS, Christiansen MG, Anikeeva P, Bhatia SN.

Nano Lett. 2016 Oct 12;16(10):6303-6310. Epub 2016 Sep 13.

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