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A feed forward loop enforces YAP/TAZ signaling during tumorigenesis.

Gill MK, Christova T, Zhang YY, Gregorieff A, Zhang L, Narimatsu M, Song S, Xiong S, Couzens AL, Tong J, Krieger JR, Moran MF, Zlotta AR, van der Kwast TH, Gingras AC, Sicheri F, Wrana JL, Attisano L.

Nat Commun. 2018 Aug 29;9(1):3510. doi: 10.1038/s41467-018-05939-2.


Recent advances in understanding contextual TGFβ signaling.

Ayyaz A, Attisano L, Wrana JL.

F1000Res. 2017 May 26;6:749. doi: 10.12688/f1000research.11295.1. eCollection 2017. Review.


MARK4 inhibits Hippo signaling to promote proliferation and migration of breast cancer cells.

Heidary Arash E, Shiban A, Song S, Attisano L.

EMBO Rep. 2017 Mar;18(3):420-436. doi: 10.15252/embr.201642455. Epub 2017 Feb 9.


DLG5 connects cell polarity and Hippo signaling protein networks by linking PAR-1 with MST1/2.

Kwan J, Sczaniecka A, Heidary Arash E, Nguyen L, Chen CC, Ratkovic S, Klezovitch O, Attisano L, McNeill H, Emili A, Vasioukhin V.

Genes Dev. 2016 Dec 15;30(24):2696-2709. doi: 10.1101/gad.284539.116.


Analysis of Hippo and TGFβ signaling in polarizing epithelial cells and mouse embryos.

Narimatsu M, Labibi B, Wrana JL, Attisano L.

Differentiation. 2016 Apr-Jun;91(4-5):109-18. doi: 10.1016/j.diff.2016.01.003. Epub 2016 Jan 21.


SGK1 (glucose transport), dishevelled2 (wnt signaling), LC3/p62 (autophagy) and p53 (apoptosis) proteins are unaltered in Lafora disease.

Wang P, Israelian L, Xue Y, Song S, Attisano L, Minassian BA.

All Results J Biol. 2016;7(3):28-33.


Arhgef7 promotes activation of the Hippo pathway core kinase Lats.

Heidary Arash E, Song KM, Song S, Shiban A, Attisano L.

EMBO J. 2014 Dec 17;33(24):2997-3011. doi: 10.15252/embj.201490230. Epub 2014 Nov 25.


p21-Activated kinase (PAK) is required for Bone Morphogenetic Protein (BMP)-induced dendritogenesis in cortical neurons.

Podkowa M, Christova T, Zhao X, Jian Y, Attisano L.

Mol Cell Neurosci. 2013 Nov;57:83-92. doi: 10.1016/j.mcn.2013.10.005. Epub 2013 Oct 16.


The TGFbeta superfamily signaling pathway.

Weiss A, Attisano L.

Wiley Interdiscip Rev Dev Biol. 2013 Jan-Feb;2(1):47-63. doi: 10.1002/wdev.86. Epub 2012 Oct 5. Review.


Signal integration in TGF-β, WNT, and Hippo pathways.

Attisano L, Wrana JL.

F1000Prime Rep. 2013 Jun 3;5:17. doi: 10.12703/P5-17. Print 2013.


A role for Hipk in the Hippo pathway.

Heidary Arash E, Attisano L.

Sci Signal. 2013 May 14;6(275):pe18. doi: 10.1126/scisignal.2004259. Review.


The return of Dr Jekyll in cancer metastasis.

Attisano L, Wrana JL.

EMBO J. 2012 Dec 12;31(24):4486-7. doi: 10.1038/emboj.2012.316. Epub 2012 Nov 27. No abstract available.


Inhibition of tankyrases induces Axin stabilization and blocks Wnt signalling in breast cancer cells.

Bao R, Christova T, Song S, Angers S, Yan X, Attisano L.

PLoS One. 2012;7(11):e48670. doi: 10.1371/journal.pone.0048670. Epub 2012 Nov 7.


Wnt inhibitor screen reveals iron dependence of β-catenin signaling in cancers.

Song S, Christova T, Perusini S, Alizadeh S, Bao RY, Miller BW, Hurren R, Jitkova Y, Gronda M, Isaac M, Joseph B, Subramaniam R, Aman A, Chau A, Hogge DE, Weir SJ, Kasper J, Schimmer AD, Al-awar R, Wrana JL, Attisano L.

Cancer Res. 2011 Dec 15;71(24):7628-39. doi: 10.1158/0008-5472.CAN-11-2745. Epub 2011 Oct 18.


Naked1 antagonizes Wnt signaling by preventing nuclear accumulation of β-catenin.

Van Raay TJ, Fortino NJ, Miller BW, Ma H, Lau G, Li C, Franklin JL, Attisano L, Solnica-Krezel L, Coffey RJ.

PLoS One. 2011 Apr 7;6(4):e18650. doi: 10.1371/journal.pone.0018650.


A skeleton in the closet: neogenin guides bone development.

Podkowa M, Attisano L.

Dev Cell. 2010 Jul 20;19(1):1-2. doi: 10.1016/j.devcel.2010.07.004.


The Hippo pathway regulates Wnt/beta-catenin signaling.

Varelas X, Miller BW, Sopko R, Song S, Gregorieff A, Fellouse FA, Sakuma R, Pawson T, Hunziker W, McNeill H, Wrana JL, Attisano L.

Dev Cell. 2010 Apr 20;18(4):579-91. doi: 10.1016/j.devcel.2010.03.007.


Microtubule stabilization by bone morphogenetic protein receptor-mediated scaffolding of c-Jun N-terminal kinase promotes dendrite formation.

Podkowa M, Zhao X, Chow CW, Coffey ET, Davis RJ, Attisano L.

Mol Cell Biol. 2010 May;30(9):2241-50. doi: 10.1128/MCB.01166-09. Epub 2010 Feb 22.


Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway.

Miller BW, Lau G, Grouios C, Mollica E, Barrios-Rodiles M, Liu Y, Datti A, Morris Q, Wrana JL, Attisano L.

Mol Syst Biol. 2009;5:315. doi: 10.1038/msb.2009.72. Epub 2009 Oct 13.


Regulation of planar cell polarity by Smurf ubiquitin ligases.

Narimatsu M, Bose R, Pye M, Zhang L, Miller B, Ching P, Sakuma R, Luga V, Roncari L, Attisano L, Wrana JL.

Cell. 2009 Apr 17;137(2):295-307. doi: 10.1016/j.cell.2009.02.025.

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