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Discovery of Distinctin-Like-Peptide-PH (DLP-PH) From the Skin Secretion of <i>Phyllomedusa hypochondrialis</i>, a Prototype of a Novel Family of Antimicrobial Peptide.

Wu D, Gao Y, Tan Y, Liu Y, Wang L, Zhou M, Xi X, Ma C, Bininda-Emonds ORP, Chen T, Shaw C.

Front Microbiol. 2018 Mar 23;9:541. doi: 10.3389/fmicb.2018.00541. eCollection 2018.


Assessment of antimicrobial and wound healing effects of Brevinin-2Ta against the bacterium <i>Klebsiella pneumoniae</i> in dermally-wounded rats.

Liu S, Long Q, Xu Y, Wang J, Xu Z, Wang L, Zhou M, Wu Y, Chen T, Shaw C.

Oncotarget. 2017 Nov 30;8(67):111369-111385. doi: 10.18632/oncotarget.22797. eCollection 2017 Dec 19.


Comparative transcriptome analyses reveal the genetic basis underlying the immune function of three amphibians' skin.

Fan W, Jiang Y, Zhang M, Yang D, Chen Z, Sun H, Lan X, Yan F, Xu J, Yuan W.

PLoS One. 2017 Dec 21;12(12):e0190023. doi: 10.1371/journal.pone.0190023. eCollection 2017.


Bioinformatic analysis reveals new determinants of antigenic 14-3-3 proteins and a novel antifungal strategy.

McGowan JE, Kratch J, Chattopadhyay S, Joe B, Conti HR, Chakravarti R.

PLoS One. 2017 Dec 12;12(12):e0189503. doi: 10.1371/journal.pone.0189503. eCollection 2017.


Antimicrobial peptides in frog poisons constitute a molecular toxin delivery system against predators.

Raaymakers C, Verbrugghe E, Hernot S, Hellebuyck T, Betti C, Peleman C, Claeys M, Bert W, Caveliers V, Ballet S, Martel A, Pasmans F, Roelants K.

Nat Commun. 2017 Nov 14;8(1):1495. doi: 10.1038/s41467-017-01710-1.


Studies of the antitumor mechanism of action of dermaseptin B2, a multifunctional cationic antimicrobial peptide, reveal a partial implication of cell surface glycosaminoglycans.

Dos Santos C, Hamadat S, Le Saux K, Newton C, Mazouni M, Zargarian L, Miro-Padovani M, Zadigue P, Delbé J, Hamma-Kourbali Y, Amiche M.

PLoS One. 2017 Aug 10;12(8):e0182926. doi: 10.1371/journal.pone.0182926. eCollection 2017.


Influence of Amphibian Antimicrobial Peptides and Short Lipopeptides on Bacterial Biofilms Formed on Contact Lenses.

Maciejewska M, Bauer M, Neubauer D, Kamysz W, Dawgul M.

Materials (Basel). 2016 Oct 26;9(11). pii: E873. doi: 10.3390/ma9110873.


Retro analog concept: comparative study on physico-chemical and biological properties of selected antimicrobial peptides.

Neubauer D, Jaśkiewicz M, Migoń D, Bauer M, Sikora K, Sikorska E, Kamysz E, Kamysz W.

Amino Acids. 2017 Oct;49(10):1755-1771. doi: 10.1007/s00726-017-2473-7. Epub 2017 Jul 29.


The first identified cathelicidin from tree frogs possesses anti-inflammatory and partial LPS neutralization activities.

Mu L, Zhou L, Yang J, Zhuang L, Tang J, Liu T, Wu J, Yang H.

Amino Acids. 2017 Sep;49(9):1571-1585. doi: 10.1007/s00726-017-2449-7. Epub 2017 Jun 7.


Targeted Modification of a Novel Amphibian Antimicrobial Peptide from <i>Phyllomedusa tarsius</i> to Enhance Its Activity against MRSA and Microbial Biofilm.

Gao Y, Wu D, Wang L, Lin C, Ma C, Xi X, Zhou M, Duan J, Bininda-Emonds ORP, Chen T, Shaw C.

Front Microbiol. 2017 Apr 19;8:628. doi: 10.3389/fmicb.2017.00628. eCollection 2017.


Searching for new strategies against biofilm infections: Colistin-AMP combinations against Pseudomonas aeruginosa and Staphylococcus aureus single- and double-species biofilms.

Jorge P, Grzywacz D, Kamysz W, Lourenço A, Pereira MO.

PLoS One. 2017 Mar 29;12(3):e0174654. doi: 10.1371/journal.pone.0174654. eCollection 2017.


Investigating the nucleic acid interactions of histone-derived antimicrobial peptides.

Sim S, Wang P, Beyer BN, Cutrona KJ, Radhakrishnan ML, Elmore DE.

FEBS Lett. 2017 Mar;591(5):706-717. doi: 10.1002/1873-3468.12574. Epub 2017 Mar 1.


Structure and membrane interactions of the homodimeric antibiotic peptide homotarsinin.

Verly RM, Resende JM, Junior EF, de Magalhães MT, Guimarães CF, Munhoz VH, Bemquerer MP, Almeida FC, Santoro MM, Piló-Veloso D, Bechinger B.

Sci Rep. 2017 Jan 19;7:40854. doi: 10.1038/srep40854.


Life history linked to immune investment in developing amphibians.

Woodhams DC, Bell SC, Bigler L, Caprioli RM, Chaurand P, Lam BA, Reinert LK, Stalder U, Vazquez VM, Schliep K, Hertz A, Rollins-Smith LA.

Conserv Physiol. 2016 Aug 26;4(1):cow025. eCollection 2016.


Novel Conopeptides of Largely Unexplored Indo Pacific Conus sp.

Lebbe EK, Ghequire MG, Peigneur S, Mille BG, Devi P, Ravichandran S, Waelkens E, D'Souza L, De Mot R, Tytgat J.

Mar Drugs. 2016 Oct 27;14(11). pii: E199.


Esculentin-1a-Derived Peptides Promote Clearance of Pseudomonas aeruginosa Internalized in Bronchial Cells of Cystic Fibrosis Patients and Lung Cell Migration: Biochemical Properties and a Plausible Mode of Action.

Cappiello F, Di Grazia A, Segev-Zarko LA, Scali S, Ferrera L, Galietta L, Pini A, Shai Y, Di YP, Mangoni ML.

Antimicrob Agents Chemother. 2016 Nov 21;60(12):7252-7262. Print 2016 Dec.


Discovery of Novel Bacterial Cell-Penetrating Phylloseptins in Defensive Skin Secretions of the South American Hylid Frogs, Phyllomedusa duellmani and Phyllomedusa coelestis.

Yang N, Li L, Wu D, Gao Y, Xi X, Zhou M, Wang L, Chen T, Shaw C.

Toxins (Basel). 2016 Aug 31;8(9). pii: E255. doi: 10.3390/toxins8090255.


Stimulation of Slack K(+) Channels Alters Mass at the Plasma Membrane by Triggering Dissociation of a Phosphatase-Regulatory Complex.

Fleming MR, Brown MR, Kronengold J, Zhang Y, Jenkins DP, Barcia G, Nabbout R, Bausch AE, Ruth P, Lukowski R, Navaratnam DS, Kaczmarek LK.

Cell Rep. 2016 Aug 30;16(9):2281-8. doi: 10.1016/j.celrep.2016.07.024. Epub 2016 Aug 18.


Temporizin and Temporizin-1 Peptides as Novel Candidates for Eliminating Trypanosoma cruzi.

Souza AL, Faria RX, Calabrese KS, Hardoim DJ, Taniwaki N, Alves LA, De Simone SG.

PLoS One. 2016 Jul 6;11(7):e0157673. doi: 10.1371/journal.pone.0157673. eCollection 2016.

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