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Items: 1 to 20 of 154

1.

Short-term administration of iso-α-acids increases transthyretin transcription in the hippocampus.

Fukuda T, Uchida K, Nakayama H, Ano Y.

Biochem Biophys Res Commun. 2018 Dec 9;507(1-4):471-475. doi: 10.1016/j.bbrc.2018.11.066. Epub 2018 Nov 17.

PMID:
30458988
2.

Copper mediated amyloid-β binding to Transthyretin.

Ciccone L, Fruchart-Gaillard C, Mourier G, Savko M, Nencetti S, Orlandini E, Servent D, Stura EA, Shepard W.

Sci Rep. 2018 Sep 13;8(1):13744. doi: 10.1038/s41598-018-31808-5.

3.

Cellular clearance of circulating transthyretin decreases cell-nonautonomous proteotoxicity in Caenorhabditis elegans.

Madhivanan K, Greiner ER, Alves-Ferreira M, Soriano-Castell D, Rouzbeh N, Aguirre CA, Paulsson JF, Chapman J, Jiang X, Ooi FK, Lemos C, Dillin A, Prahlad V, Kelly JW, Encalada SE.

Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7710-E7719. doi: 10.1073/pnas.1801117115. Epub 2018 Jul 30.

PMID:
30061394
4.

Retinol-Binding Protein Interferes with Transthyretin-Mediated β-Amyloid Aggregation Inhibition.

Mangrolia P, Murphy RM.

Biochemistry. 2018 Aug 21;57(33):5029-5040. doi: 10.1021/acs.biochem.8b00517. Epub 2018 Aug 1.

PMID:
30024734
5.

Transthyretin Interferes with Aβ Amyloid Formation by Redirecting Oligomeric Nuclei into Non-Amyloid Aggregates.

Nilsson L, Pamrén A, Islam T, Brännström K, Golchin SA, Pettersson N, Iakovleva I, Sandblad L, Gharibyan AL, Olofsson A.

J Mol Biol. 2018 Aug 17;430(17):2722-2733. doi: 10.1016/j.jmb.2018.06.005. Epub 2018 Jun 8.

PMID:
29890120
6.

Q-Rich Yeast Prion [PSI+] Accelerates Aggregation of Transthyretin, a Non-Q-Rich Human Protein.

Verma M, Girdhar A, Patel B, Ganguly NK, Kukreti R, Taneja V.

Front Mol Neurosci. 2018 Mar 13;11:75. doi: 10.3389/fnmol.2018.00075. eCollection 2018.

7.

Transthyretin Mimetics as Anti-β-Amyloid Agents: A Comparison of Peptide and Protein Approaches.

Pate KM, Kim BJ, Shusta EV, Murphy RM.

ChemMedChem. 2018 May 8;13(9):968-979. doi: 10.1002/cmdc.201800031. Epub 2018 Apr 16.

8.

Amyloid fibril polymorphism: a challenge for molecular imaging and therapy.

Fändrich M, Nyström S, Nilsson KPR, Böckmann A, LeVine H 3rd, Hammarström P.

J Intern Med. 2018 Mar;283(3):218-237. doi: 10.1111/joim.12732. Epub 2018 Feb 19.

PMID:
29360284
9.

Inhibition of curli assembly and Escherichia coli biofilm formation by the human systemic amyloid precursor transthyretin.

Jain N, Ådén J, Nagamatsu K, Evans ML, Li X, McMichael B, Ivanova MI, Almqvist F, Buxbaum JN, Chapman MR.

Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12184-12189. doi: 10.1073/pnas.1708805114. Epub 2017 Oct 30.

10.

Transthyretin neuroprotection in Alzheimer's disease is dependent on proteolysis.

Silva CS, Eira J, Ribeiro CA, Oliveira Â, Sousa MM, Cardoso I, Liz MA.

Neurobiol Aging. 2017 Nov;59:10-14. doi: 10.1016/j.neurobiolaging.2017.07.002. Epub 2017 Jul 15.

PMID:
28780366
11.

Hydrolysis and Dissolution of Amyloids by Catabodies.

Meretoja VV, Paul S, Planque SA.

Methods Mol Biol. 2017;1643:111-134. doi: 10.1007/978-1-4939-7180-0_9. Erratum in: Methods Mol Biol. 2017;1643:E1.

PMID:
28667533
12.

Insights on the Interaction between Transthyretin and Aβ in Solution. A Saturation Transfer Difference (STD) NMR Analysis of the Role of Iododiflunisal.

Gimeno A, Santos LM, Alemi M, Rivas J, Blasi D, Cotrina EY, Llop J, Valencia G, Cardoso I, Quintana J, Arsequell G, Jiménez-Barbero J.

J Med Chem. 2017 Jul 13;60(13):5749-5758. doi: 10.1021/acs.jmedchem.7b00428. Epub 2017 Jun 16.

PMID:
28587455
13.

Transthyretin stability is critical in assisting beta amyloid clearance- Relevance of transthyretin stabilization in Alzheimer's disease.

Alemi M, Silva SC, Santana I, Cardoso I.

CNS Neurosci Ther. 2017 Jul;23(7):605-619. doi: 10.1111/cns.12707. Epub 2017 Jun 1.

PMID:
28570028
14.

Transthyretin and BRICHOS: The Paradox of Amyloidogenic Proteins with Anti-Amyloidogenic Activity for Aβ in the Central Nervous System.

Buxbaum JN, Johansson J.

Front Neurosci. 2017 Mar 15;11:119. doi: 10.3389/fnins.2017.00119. eCollection 2017. Review.

15.

Positron emission tomography (PET) utilizing Pittsburgh compound B (PIB) for detection of amyloid heart deposits in hereditary transthyretin amyloidosis (ATTR).

Pilebro B, Arvidsson S, Lindqvist P, Sundström T, Westermark P, Antoni G, Suhr O, Sörensen J.

J Nucl Cardiol. 2018 Feb;25(1):240-248. doi: 10.1007/s12350-016-0638-5. Epub 2016 Sep 19.

PMID:
27645889
16.

A New Folding Kinetic Mechanism for Human Transthyretin and the Influence of the Amyloidogenic V30M Mutation.

Jesus CS, Almeida ZL, Vaz DC, Faria TQ, Brito RM.

Int J Mol Sci. 2016 Aug 31;17(9). pii: E1428. doi: 10.3390/ijms17091428.

17.

Rare Genetic Variants of the Transthyretin Gene Are Associated with Alzheimer's Disease in Han Chinese.

Xiang Q, Bi R, Xu M, Zhang DF, Tan L, Zhang C, Fang Y, Yao YG.

Mol Neurobiol. 2017 Sep;54(7):5192-5200. doi: 10.1007/s12035-016-0065-2. Epub 2016 Aug 25.

PMID:
27562180
18.

Cerebral amyloid angiopathy in posttransplant patients with hereditary ATTR amyloidosis.

Sekijima Y, Yazaki M, Oguchi K, Ezawa N, Yoshinaga T, Yamada M, Yahikozawa H, Watanabe M, Kametani F, Ikeda S.

Neurology. 2016 Aug 23;87(8):773-81. doi: 10.1212/WNL.0000000000003001. Epub 2016 Jul 27.

PMID:
27466465
19.

Gd-nanoparticles functionalization with specific peptides for ß-amyloid plaques targeting.

Plissonneau M, Pansieri J, Heinrich-Balard L, Morfin JF, Stransky-Heilkron N, Rivory P, Mowat P, Dumoulin M, Cohen R, Allémann É, Tόth É, Saraiva MJ, Louis C, Tillement O, Forge V, Lux F, Marquette C.

J Nanobiotechnology. 2016 Jul 25;14(1):60. doi: 10.1186/s12951-016-0212-y.

20.

Human TTR conformation altered by rhenium tris-carbonyl derivatives.

Ciccone L, Policar C, Stura EA, Shepard W.

J Struct Biol. 2016 Sep;195(3):353-364. doi: 10.1016/j.jsb.2016.07.002. Epub 2016 Jul 16.

PMID:
27402536

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