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Items: 1 to 20 of 324

1.

High detection sensitivity with antibody-based PET radioligand for amyloid beta in brain.

Fang XT, Hultqvist G, Meier SR, Antoni G, Sehlin D, Syvänen S.

Neuroimage. 2018 Oct 6;184:881-888. doi: 10.1016/j.neuroimage.2018.10.011. [Epub ahead of print]

2.

Brain Penetrating Bifunctional Erythropoietin-Transferrin Receptor Antibody Fusion Protein for Alzheimer's Disease.

Chang R, Al Maghribi A, Vanderpoel V, Vasilevko V, Cribbs DH, Boado R, Pardridge WM, Sumbria RK.

Mol Pharm. 2018 Oct 9. doi: 10.1021/acs.molpharmaceut.8b00594. [Epub ahead of print]

PMID:
30252487
3.

Marked Age-Related Changes in Brain Iron Homeostasis in Amyloid Protein Precursor Knockout Mice.

Belaidi AA, Gunn AP, Wong BX, Ayton S, Appukuttan AT, Roberts BR, Duce JA, Bush AI.

Neurotherapeutics. 2018 Aug 15. doi: 10.1007/s13311-018-0656-x. [Epub ahead of print]

PMID:
30112699
4.

Identification of the Al-binding proteins that account for aluminum neurotoxicity and transport in vivo.

Cheng D, Wang X, Xi Y, Cao J, Jiang W.

Toxicol Res (Camb). 2017 Dec 1;7(1):127-135. doi: 10.1039/c7tx00261k. eCollection 2018 Jan 1.

PMID:
30090569
5.

Transferrin receptor 1 in cancer: a new sight for cancer therapy.

Shen Y, Li X, Dong D, Zhang B, Xue Y, Shang P.

Am J Cancer Res. 2018 Jun 1;8(6):916-931. eCollection 2018. Review.

6.

Reversal of behavioral decline and neuropathology by a complex vitamin supplement involves modulation of key neurochemical stressors.

Olajide OJ, Fatoye JO, Idowu OF, Ilekoya D, Gbadamosi IT, Gbadamosi MT, Asogwa NT.

Environ Toxicol Pharmacol. 2018 Sep;62:120-131. doi: 10.1016/j.etap.2018.07.005. Epub 2018 Jul 7.

PMID:
30005307
7.

Magnetic Nanoparticles Associated PEG/PLGA Block Copolymer Targeted with Anti-Transferrin Receptor Antibodies for Alzheimer's Disease.

Cui N, Lu H, Li M.

J Biomed Nanotechnol. 2018 May 1;14(5):1017-1024. doi: 10.1166/jbn.2018.2512.

PMID:
29883571
8.

Efficient clearance of Aβ protofibrils in AβPP-transgenic mice treated with a brain-penetrating bifunctional antibody.

Syvänen S, Hultqvist G, Gustavsson T, Gumucio A, Laudon H, Söderberg L, Ingelsson M, Lannfelt L, Sehlin D.

Alzheimers Res Ther. 2018 May 24;10(1):49. doi: 10.1186/s13195-018-0377-8.

9.

Gene-gene interactions among coding genes of iron-homeostasis proteins and APOE-alleles in cognitive impairment diseases.

Tisato V, Zuliani G, Vigliano M, Longo G, Franchini E, Secchiero P, Zauli G, Paraboschi EM, Vikram Singh A, Serino ML, Ortolani B, Zurlo A, Bosi C, Greco A, Seripa D, Asselta R, Gemmati D.

PLoS One. 2018 Mar 8;13(3):e0193867. doi: 10.1371/journal.pone.0193867. eCollection 2018.

10.

Validation of the Spanish version of the Edinburgh Feeding Evaluation in Dementia Scale for older people with dementia.

Saucedo Figueredo MC, Morilla Herrera JC, San Alberto Giraldos M, López Leiva I, León Campos Á, Martí García C, García Mayor S, Kaknani Uttumchandani S, Morales Asencio JM.

PLoS One. 2018 Feb 27;13(2):e0192690. doi: 10.1371/journal.pone.0192690. eCollection 2018.

11.

Brain Shuttle Antibody for Alzheimer's Disease with Attenuated Peripheral Effector Function due to an Inverted Binding Mode.

Weber F, Bohrmann B, Niewoehner J, Fischer JAA, Rueger P, Tiefenthaler G, Moelleken J, Bujotzek A, Brady K, Singer T, Ebeling M, Iglesias A, Freskgård PO.

Cell Rep. 2018 Jan 2;22(1):149-162. doi: 10.1016/j.celrep.2017.12.019.

12.

PLGA nanoparticles modified with a BBB-penetrating peptide co-delivering Aβ generation inhibitor and curcumin attenuate memory deficits and neuropathology in Alzheimer's disease mice.

Huang N, Lu S, Liu XG, Zhu J, Wang YJ, Liu RT.

Oncotarget. 2017 Sep 15;8(46):81001-81013. doi: 10.18632/oncotarget.20944. eCollection 2017 Oct 6.

13.

Brain iron deposition analysis using susceptibility weighted imaging and its association with body iron level in patients with mild cognitive impairment.

Gao L, Jiang Z, Cai Z, Cai M, Zhang Q, Ma Y, Li G, Zhao F, Ma Q.

Mol Med Rep. 2017 Dec;16(6):8209-8215. doi: 10.3892/mmr.2017.7668. Epub 2017 Sep 29.

14.

Aspirin increases ferroportin 1 expression by inhibiting hepcidin via the JAK/STAT3 pathway in interleukin 6-treated PC-12 cells.

Huang SN, Ruan HZ, Chen MY, Zhou G, Qian ZM.

Neurosci Lett. 2018 Jan 1;662:1-5. doi: 10.1016/j.neulet.2017.10.001. Epub 2017 Oct 4.

PMID:
28987816
15.

New targeted therapies and diagnostic methods for iron overload diseases.

Kolnagou A, Kontoghiorghe CN, Kontoghiorghes GJ.

Front Biosci (Schol Ed). 2018 Jan 1;10:1-20. Review.

PMID:
28930516
16.

Potent and Selective BACE-1 Peptide Inhibitors Lower Brain Aβ Levels Mediated by Brain Shuttle Transport.

Ruderisch N, Schlatter D, Kuglstatter A, Guba W, Huber S, Cusulin C, Benz J, Rufer AC, Hoernschemeyer J, Schweitzer C, Bülau T, Gärtner A, Hoffmann E, Niewoehner J, Patsch C, Baumann K, Loetscher H, Kitas E, Freskgård PO.

EBioMedicine. 2017 Oct;24:76-92. doi: 10.1016/j.ebiom.2017.09.004. Epub 2017 Sep 7.

17.

Aluminum and Alzheimer's Disease.

Colomina MT, Peris-Sampedro F.

Adv Neurobiol. 2017;18:183-197. doi: 10.1007/978-3-319-60189-2_9. Review.

PMID:
28889268
18.

A unique glycan-isoform of transferrin in cerebrospinal fluid: A potential diagnostic marker for neurological diseases.

Hoshi K, Matsumoto Y, Ito H, Saito K, Honda T, Yamaguchi Y, Hashimoto Y.

Biochim Biophys Acta Gen Subj. 2017 Oct;1861(10):2473-2478. doi: 10.1016/j.bbagen.2017.07.005. Epub 2017 Jul 12. Review.

PMID:
28711405
19.

Myricetin ameliorates scopolamine-induced memory impairment in mice via inhibiting acetylcholinesterase and down-regulating brain iron.

Wang B, Zhong Y, Gao C, Li J.

Biochem Biophys Res Commun. 2017 Aug 19;490(2):336-342. doi: 10.1016/j.bbrc.2017.06.045. Epub 2017 Jun 12.

PMID:
28619513
20.

No Genetic Overlap Between Circulating Iron Levels and Alzheimer's Disease.

Lupton MK, Benyamin B, Proitsi P, Nyholt DR, Ferreira MA, Montgomery GW, Heath AC, Madden PA, Medland SE, Gordon SD; GERAD1 Consortium; Alzheimer’s Disease Neuroimaging Initiative, Lovestone S, Tsolaki M, Kloszewska I, Soininen H, Mecocci P, Vellas B, Powell JF, Bush AI, Wright MJ, Martin NG, Whitfield JB.

J Alzheimers Dis. 2017;59(1):85-99. doi: 10.3233/JAD-170027.

PMID:
28582860

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