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Items: 6


Mitochondrial genes are altered in blood early in Alzheimer's disease.

Lunnon K, Keohane A, Pidsley R, Newhouse S, Riddoch-Contreras J, Thubron EB, Devall M, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Schalkwyk L, Dobson R, Malik AN, Powell J, Lovestone S, Hodges A; AddNeuroMed Consortium.

Neurobiol Aging. 2017 May;53:36-47. doi: 10.1016/j.neurobiolaging.2016.12.029. Epub 2017 Jan 7.


Nuclear but not mitochondrial-encoded oxidative phosphorylation genes are altered in aging, mild cognitive impairment, and Alzheimer's disease.

Mastroeni D, Khdour OM, Delvaux E, Nolz J, Olsen G, Berchtold N, Cotman C, Hecht SM, Coleman PD.

Alzheimers Dement. 2017 May;13(5):510-519. doi: 10.1016/j.jalz.2016.09.003. Epub 2016 Oct 25.


Mitochondrial DNA sequence variation associated with dementia and cognitive function in the elderly.

Tranah GJ, Nalls MA, Katzman SM, Yokoyama JS, Lam ET, Zhao Y, Mooney S, Thomas F, Newman AB, Liu Y, Cummings SR, Harris TB, Yaffe K.

J Alzheimers Dis. 2012;32(2):357-72. doi: 10.3233/JAD-2012-120466.


A mitochondrial etiology of Alzheimer and Parkinson disease.

Coskun P, Wyrembak J, Schriner SE, Chen HW, Marciniack C, Laferla F, Wallace DC.

Biochim Biophys Acta. 2012 May;1820(5):553-64. doi: 10.1016/j.bbagen.2011.08.008. Epub 2011 Aug 16. Review.


Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication.

Coskun PE, Beal MF, Wallace DC.

Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10726-31. Epub 2004 Jul 9.

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