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Items: 1 to 20 of 116

1.

Epigenetic Factors in Late-Onset Alzheimer's Disease: MTHFR and CTH Gene Polymorphisms, Metabolic Transsulfuration and Methylation Pathways, and B Vitamins.

Román GC, Mancera-Páez O, Bernal C.

Int J Mol Sci. 2019 Jan 14;20(2). pii: E319. doi: 10.3390/ijms20020319. Review.

2.

The C677T Polymorphism of the Methylenetetrahydrofolate Reductase Gene and Susceptibility to Late-onset Alzheimer's Disease.

Yi J, Xiao L, Zhou SQ, Zhang WJ, Liu BY.

Open Med (Wars). 2019 Jan 4;14:32-40. doi: 10.1515/med-2019-0006. eCollection 2019.

3.

Early Manifestations of Brain Aging in Mice Due to Low Dietary Folate and Mild MTHFR Deficiency.

Bahous RH, Cosín-Tomás M, Deng L, Leclerc D, Malysheva O, Ho MK, Pallàs M, Kaliman P, Bedell BJ, Caudill MA, Rozen R.

Mol Neurobiol. 2018 Oct 4. doi: 10.1007/s12035-018-1375-3. [Epub ahead of print]

PMID:
30288696
4.

The Effects of Homocysteine on the Skeleton.

Saito M, Marumo K.

Curr Osteoporos Rep. 2018 Oct;16(5):554-560. doi: 10.1007/s11914-018-0469-1. Review.

PMID:
30116976
5.

Precision Medicine for Alzheimer's Disease Prevention.

Berkowitz CL, Mosconi L, Scheyer O, Rahman A, Hristov H, Isaacson RS.

Healthcare (Basel). 2018 Jul 13;6(3). pii: E82. doi: 10.3390/healthcare6030082. Review.

6.

Methylenetetrahydrofolate Reductase Deficiency Deregulates Regional Brain Amyloid-β Protein Precursor Expression and Phosphorylation Levels.

Hoffman A, Taleski G, Qian H, Wasek B, Arning E, Bottiglieri T, Sontag JM, Sontag E.

J Alzheimers Dis. 2018;64(1):223-237. doi: 10.3233/JAD-180032.

PMID:
29865064
7.

Homocysteine and Hyperhomocysteinaemia.

Zaric BL, Obradovic M, Bajic V, Haidara MA, Jovanovic M, Isenovic ER.

Curr Med Chem. 2018 Mar 12. doi: 10.2174/0929867325666180313105949. [Epub ahead of print]

PMID:
29532755
8.

Meta Analysis of Human AlzGene Database: Benefits and Limitations of Using C. elegans for the Study of Alzheimer's Disease and Co-morbid Conditions.

Vahdati Nia B, Kang C, Tran MG, Lee D, Murakami S.

Front Genet. 2017 May 12;8:55. doi: 10.3389/fgene.2017.00055. eCollection 2017.

9.

Increased Plasma Homocysteine Level is Associated with Executive Dysfunction in Type 2 Diabetic Patients with Mild Cognitive Impairment.

Tian S, Han J, Huang R, Sun J, Cai R, Shen Y, Wang S.

J Alzheimers Dis. 2017;58(4):1163-1173. doi: 10.3233/JAD-170162.

PMID:
28550262
10.

The C677T variant in MTHFR modulates associations between brain integrity, mood, and cognitive functioning in old age.

Roussotte FF, Hua X, Narr KL, Small GW, Thompson PM; Alzheimer's Disease Neuroimaging Initiative.

Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Apr;2(3):280-288. doi: 10.1016/j.bpsc.2016.09.005.

11.

Genetic effect of MTHFR C677T polymorphism on the structural covariance network and white-matter integrity in Alzheimer's disease.

Chang YT, Hsu SW, Tsai SJ, Chang YT, Huang CW, Liu ME, Chen NC, Chang WN, Hsu JL, Lee CC, Chang CC.

Hum Brain Mapp. 2017 Jun;38(6):3039-3051. doi: 10.1002/hbm.23572. Epub 2017 Mar 25.

PMID:
28342207
12.

Lack of association between MTHFR A1298C variant and Alzheimer's disease: evidence from a systematic review and cumulative meta-analysis.

Liu S, Wu Y, Liu X, Zhou J, Wang Z, He Z, Huang Z.

Neurol Res. 2017 May;39(5):426-434. doi: 10.1080/01616412.2017.1297340. Epub 2017 Mar 10. Review.

PMID:
28281392
13.

The Methylenetetrahydrofolate Reductase C677T Polymorphism and Risk for Late-Onset Alzheimer's disease: Further Evidence in an Italian Multicenter Study.

Stoccoro A, Tannorella P, Salluzzo MG, Ferri R, Romano C, Nacmias B, Siciliano G, Migliore L, Coppedè F.

J Alzheimers Dis. 2017;56(4):1451-1457. doi: 10.3233/JAD-161081.

PMID:
28211809
14.

Meta-Prediction of the Effect of Methylenetetrahydrofolate Reductase Polymorphisms and Air Pollution on Alzheimer's Disease Risk.

Wu SM, Chen ZF, Young L, Shiao SP.

Int J Environ Res Public Health. 2017 Jan 11;14(1). pii: E63. doi: 10.3390/ijerph14010063.

16.

Vascular Contributions in Alzheimer's Disease-Related Neuropathological Changes: First Autopsy Evidence from a South Asian Aging Population.

Wijesinghe P, Shankar SK, Yasha TC, Gorrie C, Amaratunga D, Hulathduwa S, Kumara KS, Samarasinghe K, Suh YH, Steinbusch HW, De Silva KR.

J Alzheimers Dis. 2016 Oct 18;54(4):1607-1618.

PMID:
27589527
17.

Genetic variation associated with the occurrence and progression of neurological disorders.

Little J, Barakat-Haddad C, Martino R, Pringsheim T, Tremlett H, McKay KA, van Lieshout P, Walsh SJ, Gomes J, Krewski D.

Neurotoxicology. 2017 Jul;61:243-264. doi: 10.1016/j.neuro.2016.09.018. Epub 2016 Oct 3. Review.

PMID:
27713094
18.

Artificial Neural Networks Link One-Carbon Metabolism to Gene-Promoter Methylation in Alzheimer's Disease.

Grossi E, Stoccoro A, Tannorella P, Migliore L, Coppedè F.

J Alzheimers Dis. 2016 Jul 1;53(4):1517-22. doi: 10.3233/JAD-160210.

PMID:
27392858
19.

Folate Pathway Gene Methylenetetrahydrofolate Reductase C677T Polymorphism and Alzheimer Disease Risk in Asian Population.

Rai V.

Indian J Clin Biochem. 2016 Jul;31(3):245-52. doi: 10.1007/s12291-015-0512-2. Epub 2015 Jun 23. Review.

20.

The C677T variant in MTHFR modulates associations between blood-based and cerebrospinal fluid biomarkers of neurodegeneration.

Roussotte FF, Narr KL, Small GW, Thompson PM; Alzheimer’s Disease Neuroimaging Initiative.

Neuroreport. 2016 Aug 17;27(12):948-51. doi: 10.1097/WNR.0000000000000636.

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