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Items: 1 to 20 of 41

1.

α1-antitrypsin mitigates NLRP3-inflammasome activation in amyloid β1-42-stimulated murine astrocytes.

Ebrahimi T, Rust M, Kaiser SN, Slowik A, Beyer C, Koczulla AR, Schulz JB, Habib P, Bach JP.

J Neuroinflammation. 2018 Sep 27;15(1):282. doi: 10.1186/s12974-018-1319-x.

2.

Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice.

Tzeng TC, Hasegawa Y, Iguchi R, Cheung A, Caffrey DR, Thatcher EJ, Mao W, Germain G, Tamburro ND, Okabe S, Heneka MT, Latz E, Futai K, Golenbock DT.

Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):9002-9007. doi: 10.1073/pnas.1801802115. Epub 2018 Aug 20.

PMID:
30127003
3.
4.

Co-Localization of Glia Maturation Factor with NLRP3 Inflammasome and Autophagosome Markers in Human Alzheimer's Disease Brain.

Ahmed ME, Iyer S, Thangavel R, Kempuraj D, Selvakumar GP, Raikwar SP, Zaheer S, Zaheer A.

J Alzheimers Dis. 2017;60(3):1143-1160. doi: 10.3233/JAD-170634.

5.

Ginsenoside Rg1 protects against neuronal degeneration induced by chronic dexamethasone treatment by inhibiting NLRP-1 inflammasomes in mice.

Zhang Y, Hu W, Zhang B, Yin Y, Zhang J, Huang D, Huang R, Li W, Li W.

Int J Mol Med. 2017 Oct;40(4):1134-1142. doi: 10.3892/ijmm.2017.3092. Epub 2017 Aug 9.

6.

Identification and validation of uterine stimulant methylergometrine as a potential inhibitor of caspase-1 activation.

García-Laínez G, Sancho M, García-Bayarri V, Orzáez M.

Apoptosis. 2017 Oct;22(10):1310-1318. doi: 10.1007/s10495-017-1405-z.

7.

Deletion of the Inflammasome Sensor Aim2 Mitigates Aβ Deposition and Microglial Activation but Increases Inflammatory Cytokine Expression in an Alzheimer Disease Mouse Model.

Wu PJ, Hung YF, Liu HY, Hsueh YP.

Neuroimmunomodulation. 2017;24(1):29-39. doi: 10.1159/000477092. Epub 2017 Jun 16.

PMID:
28618410
8.

The Role of Interleukin-18, Oxidative Stress and Metabolic Syndrome in Alzheimer's Disease.

Ojala JO, Sutinen EM.

J Clin Med. 2017 May 21;6(5). pii: E55. doi: 10.3390/jcm6050055. Review.

9.

Brain inflammasomes in stroke and depressive disorders: Regulation by oestrogen.

Slowik A, Lammerding L, Hoffmann S, Beyer C.

J Neuroendocrinol. 2018 Feb;30(2). doi: 10.1111/jne.12482. Review.

PMID:
28477436
10.

The role of NLRP3-CASP1 in inflammasome-mediated neuroinflammation and autophagy dysfunction in manganese-induced, hippocampal-dependent impairment of learning and memory ability.

Wang D, Zhang J, Jiang W, Cao Z, Zhao F, Cai T, Aschner M, Luo W.

Autophagy. 2017 May 4;13(5):914-927. doi: 10.1080/15548627.2017.1293766. Epub 2017 Feb 27.

11.

Inflammasomes as therapeutic targets for Alzheimer's disease.

White CS, Lawrence CB, Brough D, Rivers-Auty J.

Brain Pathol. 2017 Mar;27(2):223-234. doi: 10.1111/bpa.12478. Review.

PMID:
28009077
12.

Construction of AAV-rat-IL4 and Evaluation of its Modulating Effect on Aβ (1-42)-Induced Proinflammatory Cytokines in Primary Microglia and the B92 Cell Line by Quantitative PCR Assay.

Jamalidoust M, Ravanshad M, Namayandeh M, Zare M, Asaei S, Ziyaeyan M.

Jundishapur J Microbiol. 2016 Mar 5;9(3):e30444. doi: 10.5812/jjm.30444. eCollection 2016 Mar.

13.

Effect of adenovirus-mediated RNA interference of IL-1β expression on spinal cord injury in rats.

Lin WP, Lin JH, Cai B, Shi JX, Li WJ, Choudhury GR, Wu SQ, Wu JZ, Wu HP, Ke QF.

Spinal Cord. 2016 Oct;54(10):778-784. doi: 10.1038/sc.2016.20. Epub 2016 Feb 23.

PMID:
26902461
14.

Interleukin-18 -137 G/C and -607 C/A polymorphisms and Alzheimer's disease risk: a meta-analysis.

Zhang J, Song T, Liang H, Lian J, Zhang G, Gong H.

Neurol Sci. 2016 Jun;37(6):921-7. doi: 10.1007/s10072-016-2516-y. Epub 2016 Feb 20.

PMID:
26897018
15.

Epistasis analysis links immune cascades and cerebral amyloidosis.

Benedet AL, Labbe A, Lemay P, Zimmer ER, Pascoal TA, Leuzy A, Mathotaarachchi S, Mohades S, Shin M, Dionne-Laporte A, Beaudry T, Picard C, Gauthier S, Poirier J, Rouleau G, Rosa-Neto P; Alzheimer’s Disease Neuroimaging Initiative.

J Neuroinflammation. 2015 Dec 1;12:227. doi: 10.1186/s12974-015-0436-z.

16.

Targeting the NLRP3 inflammasome in chronic inflammatory diseases: current perspectives.

Ozaki E, Campbell M, Doyle SL.

J Inflamm Res. 2015 Jan 16;8:15-27. doi: 10.2147/JIR.S51250. eCollection 2015. Review.

17.

Association of IL-1, IL-18, and IL-33 gene polymorphisms with late-onset Alzheimer׳s disease in a Hunan Han Chinese population.

Tian M, Deng YY, Hou DR, Li W, Feng XL, Yu ZL.

Brain Res. 2015 Jan 30;1596:136-45. doi: 10.1016/j.brainres.2014.11.019. Epub 2014 Nov 20.

PMID:
25446437
18.

Interleukin-18 alters protein expressions of neurodegenerative diseases-linked proteins in human SH-SY5Y neuron-like cells.

Sutinen EM, Korolainen MA, Häyrinen J, Alafuzoff I, Petratos S, Salminen A, Soininen H, Pirttilä T, Ojala JO.

Front Cell Neurosci. 2014 Aug 7;8:214. doi: 10.3389/fncel.2014.00214. eCollection 2014.

19.

Increased serum levels of interleukin-18, -23 and -17 in Chinese patients with Alzheimer's disease.

Chen JM, Jiang GX, Li QW, Zhou ZM, Cheng Q.

Dement Geriatr Cogn Disord. 2014;38(5-6):321-9. doi: 10.1159/000360606. Epub 2014 Aug 13.

PMID:
25138786
20.

The impact of APOE status on relationship of biomarkers of vascular risk and systemic inflammation to neuropsychiatric symptoms in Alzheimer's disease.

Hall JR, Wiechmann AR, Johnson LA, Edwards M, Barber RC, Cunningham R, Singh M, O'Bryant SE.

J Alzheimers Dis. 2014;40(4):887-96. doi: 10.3233/JAD-131724.

PMID:
24577461

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