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Items: 1 to 20 of 160


Neuroprotective Activity of Sitagliptin via Reduction of Neuroinflammation beyond the Incretin Effect: Focus on Alzheimer's Disease.

Wiciński M, Wódkiewicz E, Słupski M, Walczak M, Socha M, Malinowski B, Pawlak-Osińska K.

Biomed Res Int. 2018 Aug 16;2018:6091014. doi: 10.1155/2018/6091014. eCollection 2018. Review.


Targeting central β2 receptors ameliorates streptozotocin-induced neuroinflammation via inhibition of glycogen synthase kinase3 pathway in mice.

Abdel Rasheed NO, El Sayed NS, El-Khatib AS.

Prog Neuropsychopharmacol Biol Psychiatry. 2018 Aug 30;86:65-75. doi: 10.1016/j.pnpbp.2018.05.010. Epub 2018 May 18.


Microglial Activation Is Modulated by Captopril: in Vitro and in Vivo Studies.

Asraf K, Torika N, Apte RN, Fleisher-Berkovich S.

Front Cell Neurosci. 2018 May 1;12:116. doi: 10.3389/fncel.2018.00116. eCollection 2018.


Aging exacerbates cognitive and anxiety alterations induced by an intracerebroventricular injection of amyloid-β1-42 peptide in mice.

Souza LC, Jesse CR, Del Fabbro L, de Gomes MG, Gomes NS, Filho CB, Goes ATR, Wilhelm EA, Luchese C, Roman SS, Boeira SP.

Mol Cell Neurosci. 2018 Apr;88:93-106. doi: 10.1016/j.mcn.2018.01.005. Epub 2018 Feb 3.


Innate immune alterations are elicited in microglial cells before plaque deposition in the Alzheimer's disease mouse model 5xFAD.

Boza-Serrano A, Yang Y, Paulus A, Deierborg T.

Sci Rep. 2018 Jan 24;8(1):1550. doi: 10.1038/s41598-018-19699-y.


Mesenchymal stem cells and cell-derived extracellular vesicles protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers.

de Godoy MA, Saraiva LM, de Carvalho LRP, Vasconcelos-Dos-Santos A, Beiral HJV, Ramos AB, Silva LRP, Leal RB, Monteiro VHS, Braga CV, de Araujo-Silva CA, Sinis LC, Bodart-Santos V, Kasai-Brunswick TH, Alcantara CL, Lima APCA, da Cunha-E Silva NL, Galina A, Vieyra A, De Felice FG, Mendez-Otero R, Ferreira ST.

J Biol Chem. 2018 Feb 9;293(6):1957-1975. doi: 10.1074/jbc.M117.807180. Epub 2017 Dec 28.


Promoter haplotypes of interleukin-10 gene linked to cortex plasticity in subjects with risk of Alzheimer's disease.

Bai F, Xie C, Yuan Y, Shi Y, Zhang Z.

Neuroimage Clin. 2017 Nov 21;17:587-595. doi: 10.1016/j.nicl.2017.11.019. eCollection 2018.


Triggering Receptor Expressed on Myeloid Cells 2 Overexpression Inhibits Proinflammatory Cytokines in Lipopolysaccharide-Stimulated Microglia.

Zhang X, Yan F, Cui J, Wu Y, Luan H, Yin M, Zhao Z, Feng J, Zhang J.

Mediators Inflamm. 2017;2017:9340610. doi: 10.1155/2017/9340610. Epub 2017 Oct 18.


Alzheimer's disease and cytokine IL-10 gene polymorphisms: is there an association?

Magalhães CA, Carvalho MDG, Sousa LP, Caramelli P, Gomes KB.

Arq Neuropsiquiatr. 2017 Sep;75(9):649-656. doi: 10.1590/0004-282X20170110. Review.


Anti-inflammatory (M2) macrophage media reduce transmission of oligomeric amyloid beta in differentiated SH-SY5Y cells.

Sackmann V, Ansell A, Sackmann C, Lund H, Harris RA, Hallbeck M, Nilsberth C.

Neurobiol Aging. 2017 Dec;60:173-182. doi: 10.1016/j.neurobiolaging.2017.08.022. Epub 2017 Sep 1.


Effects of propofol and surgery on neuropathology and cognition in the 3xTgAD Alzheimer transgenic mouse model.

Mardini F, Tang JX, Li JC, Arroliga MJ, Eckenhoff RG, Eckenhoff MF.

Br J Anaesth. 2017 Sep 1;119(3):472-480. doi: 10.1093/bja/aew397.


Immune modulation by curcumin: The role of interleukin-10.

Mollazadeh H, Cicero AFG, Blesso CN, Pirro M, Majeed M, Sahebkar A.

Crit Rev Food Sci Nutr. 2017 Aug 11:1-13. doi: 10.1080/10408398.2017.1358139. [Epub ahead of print]


Serum Interleukin-10 Levels Correlate with Cerebrospinal Fluid Amyloid Beta Deposition in Alzheimer Disease Patients.

D'Anna L, Abu-Rumeileh S, Fabris M, Pistis C, Baldi A, Sanvilli N, Curcio F, Gigli GL, D'Anna S, Valente M.

Neurodegener Dis. 2017;17(4-5):227-234. doi: 10.1159/000474940. Epub 2017 Jul 19.


Multiple lipopolysaccharide (LPS) injections alter interleukin 6 (IL-6), IL-7, IL-10 and IL-6 and IL-7 receptor mRNA in CNS and spleen.

Szot P, Franklin A, Figlewicz DP, Beuca TP, Bullock K, Hansen K, Banks WA, Raskind MA, Peskind ER.

Neuroscience. 2017 Jul 4;355:9-21. doi: 10.1016/j.neuroscience.2017.04.028. Epub 2017 Apr 27.


Highly electronegative low-density lipoprotein L5 evokes microglial activation and creates a neuroinflammatory stress via Toll-like receptor 4 signaling.

Yu LE, Lai CL, Lee CT, Wang JY.

J Neurochem. 2017 Jul;142(2):231-245. doi: 10.1111/jnc.14053. Epub 2017 May 16.


Rosuvastatin Attenuates High-Salt and Cholesterol Diet Induced Neuroinflammation and Cognitive Impairment via Preventing Nuclear Factor KappaB Pathway.

Husain I, Akhtar M, Vohora D, Abdin MZ, Islamuddin M, Akhtar MJ, Najmi AK.

Neurochem Res. 2017 Aug;42(8):2404-2416. doi: 10.1007/s11064-017-2264-2. Epub 2017 Apr 18.


Alzheimer's Disease-like Early-phase Brain Pathogenesis: Self-curing Amelioration of Neurodegeneration from Pro-inflammatory 'Wounding' to Anti-inflammatory 'Healing'.

He J, Liao T, Zhong GX, Zhang JD, Chen YP, Wang Q, Zeng QP.

Curr Alzheimer Res. 2017;14(10):1123-1135. doi: 10.2174/1567205014666170417111420.


Minocycline reduces inflammatory parameters in the brain structures and serum and reverses memory impairment caused by the administration of amyloid β (1-42) in mice.

Garcez ML, Mina F, Bellettini-Santos T, Carneiro FG, Luz AP, Schiavo GL, Andrighetti MS, Scheid MG, Bolfe RP, Budni J.

Prog Neuropsychopharmacol Biol Psychiatry. 2017 Jul 3;77:23-31. doi: 10.1016/j.pnpbp.2017.03.010. Epub 2017 Mar 21.


Immunization with Bacillus Calmette-Guérin (BCG) alleviates neuroinflammation and cognitive deficits in APP/PS1 mice via the recruitment of inflammation-resolving monocytes to the brain.

Zuo Z, Qi F, Yang J, Wang X, Wu Y, Wen Y, Yuan Q, Zou J, Guo K, Yao ZB.

Neurobiol Dis. 2017 May;101:27-39. doi: 10.1016/j.nbd.2017.02.001. Epub 2017 Feb 9.


Maysin and Its Flavonoid Derivative from Centipedegrass Attenuates Amyloid Plaques by Inducting Humoral Immune Response with Th2 Skewed Cytokine Response in the Tg (APPswe, PS1dE9) Alzheimer's Mouse Model.

Song Y, Kim HD, Lee MK, Hong IH, Won CK, Bai HW, Lee SS, Lee S, Chung BY, Cho JH.

PLoS One. 2017 Jan 10;12(1):e0169509. doi: 10.1371/journal.pone.0169509. eCollection 2017.

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