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Items: 1 to 20 of 52

1.

Gene-gene interactions among coding genes of iron-homeostasis proteins and APOE-alleles in cognitive impairment diseases.

Tisato V, Zuliani G, Vigliano M, Longo G, Franchini E, Secchiero P, Zauli G, Paraboschi EM, Vikram Singh A, Serino ML, Ortolani B, Zurlo A, Bosi C, Greco A, Seripa D, Asselta R, Gemmati D.

PLoS One. 2018 Mar 8;13(3):e0193867. doi: 10.1371/journal.pone.0193867. eCollection 2018.

2.

Pathophysiological consequences and benefits of HFE mutations: 20 years of research.

Hollerer I, Bachmann A, Muckenthaler MU.

Haematologica. 2017 May;102(5):809-817. doi: 10.3324/haematol.2016.160432. Epub 2017 Mar 9. Review.

3.

Genetic Association of HLA Gene Variants with MRI Brain Structure in Alzheimer's Disease.

Wang ZX, Wan Y, Tan L, Liu J, Wang HF, Sun FR, Tan MS, Tan CC, Jiang T, Tan L, Yu JT; Alzheimer’s Disease Neuroimaging Initiative.

Mol Neurobiol. 2017 Jul;54(5):3195-3204. doi: 10.1007/s12035-016-9889-z. Epub 2016 Apr 7.

PMID:
27056077
4.

Iron in Frontotemporal Lobar Degeneration: A New Subcortical Pathological Pathway?

Gazzina S, Premi E, Zanella I, Biasiotto G, Archetti S, Cosseddu M, Scarpini E, Galimberti D, Serpente M, Gasparotti R, Padovani A, Borroni B.

Neurodegener Dis. 2016;16(3-4):172-8. doi: 10.1159/000440843. Epub 2015 Nov 28.

PMID:
26613252
5.

The effects of okra (Abelmoschus esculentus Linn.) on the cellular events associated with Alzheimer's disease in a stably expressed HFE neuroblastoma SH-SY5Y cell line.

Mairuae N, Connor JR, Lee SY, Cheepsunthorn P, Tongjaroenbuangam W.

Neurosci Lett. 2015 Aug 31;603:6-11. doi: 10.1016/j.neulet.2015.07.011. Epub 2015 Jul 10.

PMID:
26170247
6.

Cumulative lead exposure is associated with reduced olfactory recognition performance in elderly men: The Normative Aging Study.

Grashow R, Sparrow D, Hu H, Weisskopf MG.

Neurotoxicology. 2015 Jul;49:158-64. doi: 10.1016/j.neuro.2015.06.006. Epub 2015 Jun 26.

7.

Decision tree analysis of genetic risk for clinically heterogeneous Alzheimer's disease.

Yokoyama JS, Bonham LW, Sears RL, Klein E, Karydas A, Kramer JH, Miller BL, Coppola G.

BMC Neurol. 2015 Mar 28;15:47. doi: 10.1186/s12883-015-0304-6.

8.

HFE gene variants, iron, and lipids: a novel connection in Alzheimer's disease.

Ali-Rahmani F, Schengrund CL, Connor JR.

Front Pharmacol. 2014 Jul 8;5:165. doi: 10.3389/fphar.2014.00165. eCollection 2014. Review.

9.

H63D mutation in hemochromatosis alters cholesterol metabolism and induces memory impairment.

Ali-Rahmani F, Grigson PS, Lee S, Neely E, Connor JR, Schengrund CL.

Neurobiol Aging. 2014 Jun;35(6):1511.e1-12. doi: 10.1016/j.neurobiolaging.2013.12.014. Epub 2013 Dec 25.

PMID:
24439478
10.

Study of Alzheimer family case reveals hemochromotosis-associated HFE mutation.

Artemov AV, Boulygina ES, Tsygankova SV, Nedoluzhko AV, Chekanov NN, Gruzdeva NM, Selezneva ND, Roshchina IF, Gavrilova SI, Velichkovsky BB, Skryabin KG, Prokhortchouk EB.

Hum Genome Var. 2014 Jul 31;1:14004. doi: 10.1038/hgv.2014.4. eCollection 2014.

11.

Risk factors for development of dementia in a unique six-year cohort study. I. An exploratory, pilot study of involvement of the E4 allele of apolipoprotein E, mutations of the hemochromatosis-HFE gene, type 2 diabetes, and stroke.

Percy M, Somerville MJ, Hicks M, Garcia A, Colelli T, Wright E, Kitaygorodsky J, Jiang A, Ho V, Parpia A, Wong MK.

J Alzheimers Dis. 2014;38(4):907-22. doi: 10.3233/JAD-131409.

PMID:
24081379
12.

Effects of hemochromatosis and transferrin gene mutations on peripheral iron dyshomeostasis in mild cognitive impairment and Alzheimer's and Parkinson's diseases.

Mariani S, Ventriglia M, Simonelli I, Spalletta G, Bucossi S, Siotto M, Assogna F, Melgari JM, Vernieri F, Squitti R.

Front Aging Neurosci. 2013 Aug 5;5:37. doi: 10.3389/fnagi.2013.00037. eCollection 2013.

13.

Anti-inflammatory activity of a honey flavonoid extract on lipopolysaccharide-activated N13 microglial cells.

Candiracci M, Piatti E, Dominguez-Barragán M, García-Antrás D, Morgado B, Ruano D, Gutiérrez JF, Parrado J, Castaño A.

J Agric Food Chem. 2012 Dec 19;60(50):12304-11. doi: 10.1021/jf302468h. Epub 2012 Dec 5.

PMID:
23176387
14.

Pathology supported genetic testing and treatment of cardiovascular disease in middle age for prevention of Alzheimer's disease.

Kotze MJ, van Rensburg SJ.

Metab Brain Dis. 2012 Sep;27(3):255-66. doi: 10.1007/s11011-012-9296-8. Epub 2012 Apr 19. Review.

15.

Changes in brain transcripts related to Alzheimer's disease in a model of HFE hemochromatosis are not consistent with increased Alzheimer's disease risk.

Johnstone DM, Graham RM, Trinder D, Riveros C, Olynyk JK, Scott RJ, Moscato P, Milward EA.

J Alzheimers Dis. 2012;30(4):791-803. doi: 10.3233/JAD-2012-112183.

PMID:
22466002
16.

Association between HFE polymorphisms and susceptibility to Alzheimer's disease: a meta-analysis of 22 studies including 4,365 cases and 8,652 controls.

Lin M, Zhao L, Fan J, Lian XG, Ye JX, Wu L, Lin H.

Mol Biol Rep. 2012 Mar;39(3):3089-95. doi: 10.1007/s11033-011-1072-z. Epub 2011 Jun 24.

PMID:
21701828
17.

Effects of hemochromatosis and transferrin gene mutations on iron dyshomeostasis, liver dysfunction and on the risk of Alzheimer's disease.

Giambattistelli F, Bucossi S, Salustri C, Panetta V, Mariani S, Siotto M, Ventriglia M, Vernieri F, Dell'acqua ML, Cassetta E, Rossini PM, Squitti R.

Neurobiol Aging. 2012 Aug;33(8):1633-41. doi: 10.1016/j.neurobiolaging.2011.03.005. Epub 2011 Apr 21.

PMID:
21514009
18.

Gender and iron genes may modify associations between brain iron and memory in healthy aging.

Bartzokis G, Lu PH, Tingus K, Peters DG, Amar CP, Tishler TA, Finn JP, Villablanca P, Altshuler LL, Mintz J, Neely E, Connor JR.

Neuropsychopharmacology. 2011 Jun;36(7):1375-84. doi: 10.1038/npp.2011.22. Epub 2011 Mar 9.

19.

Mutant HFE H63D protein is associated with prolonged endoplasmic reticulum stress and increased neuronal vulnerability.

Liu Y, Lee SY, Neely E, Nandar W, Moyo M, Simmons Z, Connor JR.

J Biol Chem. 2011 Apr 15;286(15):13161-70. doi: 10.1074/jbc.M110.170944. Epub 2011 Feb 24.

20.

HFE gene variants affect iron in the brain.

Nandar W, Connor JR.

J Nutr. 2011 Apr 1;141(4):729S-739S. doi: 10.3945/jn.110.130351. Epub 2011 Feb 23. Review.

PMID:
21346098

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