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BACE2, a conditional β-secretase, contributes to Alzheimer's disease pathogenesis.

Wang Z, Xu Q, Cai F, Liu X, Wu Y, Song W.

JCI Insight. 2019 Jan 10;4(1). pii: 123431. doi: 10.1172/jci.insight.123431. [Epub ahead of print]


Plasma Protein Biomarkers for the Prediction of CSF Amyloid and Tau and [18F]-Flutemetamol PET Scan Result.

Westwood S, Baird AL, Hye A, Ashton NJ, Nevado-Holgado AJ, Anand SN, Liu B, Newby D, Bazenet C, Kiddle SJ, Ward M, Newton B, Desai K, Tan Hehir C, Zanette M, Galimberti D, Parnetti L, Lleó A, Baker S, Narayan VA, van der Flier WM, Scheltens P, Teunissen CE, Visser PJ, Lovestone S.

Front Aging Neurosci. 2018 Dec 11;10:409. doi: 10.3389/fnagi.2018.00409. eCollection 2018.


Relationship between Alzheimer's disease-associated SNPs within the CLU gene, local DNA methylation and episodic verbal memory in healthy and schizophrenia subjects.

Alfimova M, Kondratyev N, Golov A, Golimbet V.

Psychiatry Res. 2018 Dec 27;272:380-386. doi: 10.1016/j.psychres.2018.12.134. [Epub ahead of print]


Diverse Protein Profiles in CNS Myeloid Cells and CNS Tissue From Lipopolysaccharide- and Vehicle-Injected APPSWE/PS1ΔE9 Transgenic Mice Implicate Cathepsin Z in Alzheimer's Disease.

Thygesen C, Ilkjær L, Kempf SJ, Hemdrup AL, von Linstow CU, Babcock AA, Darvesh S, Larsen MR, Finsen B.

Front Cell Neurosci. 2018 Nov 6;12:397. doi: 10.3389/fncel.2018.00397. eCollection 2018.


Blood-based redox-signature and their association to the cognitive scores in MCI and Alzheimer's disease patients.

Perrotte M, Le Page A, Fournet M, Le Sayec M, Rassart É, Fulop T, Ramassamy C.

Free Radic Biol Med. 2019 Jan;130:499-511. doi: 10.1016/j.freeradbiomed.2018.10.452. Epub 2018 Nov 13.


New genetic players in late-onset Alzheimer's disease: Findings of genome-wide association studies.

Misra A, Chakrabarti SS, Gambhir IS.

Indian J Med Res. 2018 Aug;148(2):135-144. doi: 10.4103/ijmr.IJMR_473_17. Review.


The Reelin Receptors Apolipoprotein E receptor 2 (ApoER2) and VLDL Receptor.

Dlugosz P, Nimpf J.

Int J Mol Sci. 2018 Oct 9;19(10). pii: E3090. doi: 10.3390/ijms19103090. Review.


Clusterin contributes to early stage of Alzheimer's disease pathogenesis.

Oh SB, Kim MS, Park S, Son H, Kim SY, Kim MS, Jo DG, Tak E, Lee JY.

Brain Pathol. 2018 Oct 8. doi: 10.1111/bpa.12660. [Epub ahead of print]


Association between clusterin concentration and dementia: a systematic review and meta-analysis.

Yang C, Wang H, Li C, Niu H, Luo S, Guo X.

Metab Brain Dis. 2018 Oct 5. doi: 10.1007/s11011-018-0325-0. [Epub ahead of print]


Biomarkers of dementia in obstructive sleep apnea.

Baril AA, Carrier J, Lafrenière A, Warby S, Poirier J, Osorio RS, Ayas N, Dubé MP, Petit D, Gosselin N; Canadian Sleep and Circadian Network.

Sleep Med Rev. 2018 Dec;42:139-148. doi: 10.1016/j.smrv.2018.08.001. Epub 2018 Aug 13. Review.


Plasma Aβ42 as Biomarker of Prodromal Alzheimer's Disease Progression in Patients with Amnestic Mild Cognitive Impairment: Evidence from the PharmaCog/E-ADNI Study.

Albani D, Marizzoni M, Ferrari C, Fusco F, Boeri L, Raimondi I, Jovicich J, Babiloni C, Soricelli A, Lizio R, Galluzzi S, Cavaliere L, Didic M, Schönknecht P, Molinuevo JL, Nobili F, Parnetti L, Payoux P, Bocchio L, Salvatore M, Rossini PM, Tsolaki M, Visser PJ, Richardson JC, Wiltfang J, Bordet R, Blin O, Forloni G, Frisoni GB, Consortium P.

J Alzheimers Dis. 2018 Aug 20. doi: 10.3233/JAD-180321. [Epub ahead of print]


Clusterin Is Required for β-Amyloid Toxicity in Human iPSC-Derived Neurons.

Robbins JP, Perfect L, Ribe EM, Maresca M, Dangla-Valls A, Foster EM, Killick R, Nowosiad P, Reid MJ, Polit LD, Nevado AJ, Ebner D, Bohlooly-Y M, Buckley N, Pangalos MN, Price J, Lovestone S.

Front Neurosci. 2018 Jul 25;12:504. doi: 10.3389/fnins.2018.00504. eCollection 2018.


A Role for Clusterin in Exfoliation Syndrome and Exfoliation Glaucoma?

Wiggs JL, Kang JH, Fan B, Levkovitch-Verbin H, Pasquale LR.

J Glaucoma. 2018 Jul;27 Suppl 1:S61-S66. doi: 10.1097/IJG.0000000000000916.


Relevance of N-terminal residues for amyloid-β binding to platelet integrin αIIbβ3, integrin outside-in signaling and amyloid-β fibril formation.

Donner L, Gremer L, Ziehm T, Gertzen CGW, Gohlke H, Willbold D, Elvers M.

Cell Signal. 2018 Oct;50:121-130. doi: 10.1016/j.cellsig.2018.06.015. Epub 2018 Jun 30.


A Genome-Wide Association Study of α-Synuclein Levels in Cerebrospinal Fluid.

Zhong XL, Li JQ, Sun L, Li YQ, Wang HF, Cao XP, Tan CC, Wang L, Tan L, Yu JT; Alzheimer’s Disease Neuroimaging Initiative.

Neurotox Res. 2019 Jan;35(1):41-48. doi: 10.1007/s12640-018-9922-2. Epub 2018 Jun 29.


7B2 chaperone knockout in APP model mice results in reduced plaque burden.

Jarvela TS, Womack T, Georgiou P, Gould TD, Eriksen JL, Lindberg I.

Sci Rep. 2018 Jun 28;8(1):9813. doi: 10.1038/s41598-018-28031-7.


Biomarkers of agitation and aggression in Alzheimer's disease: A systematic review.

Ruthirakuhan M, Lanctôt KL, Di Scipio M, Ahmed M, Herrmann N.

Alzheimers Dement. 2018 Oct;14(10):1344-1376. doi: 10.1016/j.jalz.2018.04.013. Epub 2018 Jun 23.


Proteomics analysis identifies new markers associated with capillary cerebral amyloid angiopathy in Alzheimer's disease.

Hondius DC, Eigenhuis KN, Morrema THJ, van der Schors RC, van Nierop P, Bugiani M, Li KW, Hoozemans JJM, Smit AB, Rozemuller AJM.

Acta Neuropathol Commun. 2018 Jun 4;6(1):46. doi: 10.1186/s40478-018-0540-2.


Platelets: Peripheral Biomarkers of Dementia?

Akingbade OES, Gibson C, Kalaria RN, Mukaetova-Ladinska EB.

J Alzheimers Dis. 2018;63(4):1235-1259. doi: 10.3233/JAD-180181.


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