Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 45


Chemical synapses without synaptic vesicles: Purinergic neurotransmission through a CALHM1 channel-mitochondrial signaling complex.

Romanov RA, Lasher RS, High B, Savidge LE, Lawson A, Rogachevskaja OA, Zhao H, Rogachevsky VV, Bystrova MF, Churbanov GD, Adameyko I, Harkany T, Yang R, Kidd GJ, Marambaud P, Kinnamon JC, Kolesnikov SS, Finger TE.

Sci Signal. 2018 May 8;11(529). pii: eaao1815. doi: 10.1126/scisignal.aao1815.


When, where and how? Focus on neuronal calcium dysfunctions in Alzheimer's Disease.

Agostini M, Fasolato C.

Cell Calcium. 2016 Nov;60(5):289-298. doi: 10.1016/j.ceca.2016.06.008. Epub 2016 Jul 9. Review.


ERK1/2 activation in human taste bud cells regulates fatty acid signaling and gustatory perception of fat in mice and humans.

Subramaniam S, Ozdener MH, Abdoul-Azize S, Saito K, Malik B, Maquart G, Hashimoto T, Marambaud P, Aribi M, Tordoff MG, Besnard P, Khan NA.

FASEB J. 2016 Oct;30(10):3489-3500. Epub 2016 Jun 29.


CALHM1 deficiency impairs cerebral neuron activity and memory flexibility in mice.

Vingtdeux V, Chang EH, Frattini SA, Zhao H, Chandakkar P, Adrien L, Strohl JJ, Gibson EL, Ohmoto M, Matsumoto I, Huerta PT, Marambaud P.

Sci Rep. 2016 Apr 12;6:24250. doi: 10.1038/srep24250.


Calcium homeostasis modulator 1 gene P86L polymorphism and the risk for alzheimer's disease: A meta-analysis.

Mun MJ, Kim JH, Choi JY, Jang WC.

Neurosci Lett. 2016 Apr 21;619:8-14. doi: 10.1016/j.neulet.2016.02.049. Epub 2016 Mar 2.


Genetic association of CALHM1 rs2986017 polymorphism with risk of Alzheimer's disease: a meta-analysis.

Lu Y, Liu W, Tan K, Peng J, Zhu Y, Wang X.

Neurol Sci. 2016 Apr;37(4):525-32. doi: 10.1007/s10072-015-2451-3. Epub 2015 Dec 23.


CALHM1 and its polymorphism P86L differentially control Ca²⁺homeostasis, mitogen-activated protein kinase signaling, and cell vulnerability upon exposure to amyloid β.

Moreno-Ortega AJ, Buendia I, Mouhid L, Egea J, Lucea S, Ruiz-Nuño A, López MG, Cano-Abad MF.

Aging Cell. 2015 Dec;14(6):1094-102. doi: 10.1111/acel.12403. Epub 2015 Sep 29.


Candidate genes for Alzheimer's disease are associated with individual differences in plasma levels of beta amyloid peptides in adults with Down syndrome.

Schupf N, Lee A, Park N, Dang LH, Pang D, Yale A, Oh DK, Krinsky-McHale SJ, Jenkins EC, Luchsinger JA, Zigman WB, Silverman W, Tycko B, Kisselev S, Clark L, Lee JH.

Neurobiol Aging. 2015 Oct;36(10):2907.e1-10. doi: 10.1016/j.neurobiolaging.2015.06.020. Epub 2015 Jun 19.


CALHM1 ion channel elicits amyloid-β clearance by insulin-degrading enzyme in cell lines and in vivo in the mouse brain.

Vingtdeux V, Chandakkar P, Zhao H, Blanc L, Ruiz S, Marambaud P.

J Cell Sci. 2015 Jul 1;128(13):2330-8. doi: 10.1242/jcs.167270. Epub 2015 May 21.


CALHM1 Deletion in Mice Affects Glossopharyngeal Taste Responses, Food Intake, Body Weight, and Life Span.

Hellekant G, Schmolling J, Marambaud P, Rose-Hellekant TA.

Chem Senses. 2015 Jul;40(6):373-9. doi: 10.1093/chemse/bjv009. Epub 2015 Apr 8.


Effect of the CALHM1 G330D and R154H human variants on the control of cytosolic Ca2+ and Aβ levels.

Vingtdeux V, Tanis JE, Chandakkar P, Zhao H, Dreses-Werringloer U, Campagne F, Foskett JK, Marambaud P.

PLoS One. 2014 Nov 11;9(11):e112484. doi: 10.1371/journal.pone.0112484. eCollection 2014.


Salty taste deficits in CALHM1 knockout mice.

Tordoff MG, Ellis HT, Aleman TR, Downing A, Marambaud P, Foskett JK, Dana RM, McCaughey SA.

Chem Senses. 2014 Jul;39(6):515-28. doi: 10.1093/chemse/bju020. Epub 2014 May 20.


Lack of association between CALHM1 p.P86L variation and Alzheimer's disease in the Han Chinese population.

Tao QQ, Sun YM, Liu ZJ, Yang P, Li HL, Lu SJ, Wu ZY.

Neurobiol Aging. 2014 Aug;35(8):1956.e13-4. doi: 10.1016/j.neurobiolaging.2014.02.013. Epub 2014 Feb 20.


Sucrose-conditioned flavor preferences in sweet ageusic T1r3 and Calhm1 knockout mice.

Sclafani A, Marambaud P, Ackroff K.

Physiol Behav. 2014 Mar 14;126:25-9. doi: 10.1016/j.physbeh.2013.12.003. Epub 2013 Dec 31.


Rare variants in calcium homeostasis modulator 1 (CALHM1) found in early onset Alzheimer's disease patients alter calcium homeostasis.

Rubio-Moscardo F, Setó-Salvia N, Pera M, Bosch-Morató M, Plata C, Belbin O, Gené G, Dols-Icardo O, Ingelsson M, Helisalmi S, Soininen H, Hiltunen M, Giedraitis V, Lannfelt L, Frank A, Bullido MJ, Combarros O, Sánchez-Juan P, Boada M, Tárraga L, Pastor P, Pérez-Tur J, Baquero M, Molinuevo JL, Sánchez-Valle R, Fuentes-Prior P, Fortea J, Blesa R, Muñoz FJ, Lleó A, Valverde MA, Clarimón J.

PLoS One. 2013 Sep 17;8(9):e74203. doi: 10.1371/journal.pone.0074203. eCollection 2013.


CLHM-1 is a functionally conserved and conditionally toxic Ca2+-permeable ion channel in Caenorhabditis elegans.

Tanis JE, Ma Z, Krajacic P, He L, Foskett JK, Lamitina T.

J Neurosci. 2013 Jul 24;33(30):12275-86. doi: 10.1523/JNEUROSCI.5919-12.2013.


CALHM1 controls the Ca²⁺-dependent MEK, ERK, RSK and MSK signaling cascade in neurons.

Dreses-Werringloer U, Vingtdeux V, Zhao H, Chandakkar P, Davies P, Marambaud P.

J Cell Sci. 2013 Mar 1;126(Pt 5):1199-206. doi: 10.1242/jcs.117135. Epub 2013 Jan 23.


Genetic variability of the gene cluster CALHM 1-3 in sporadic Creutzfeldt-Jakob disease.

Calero O, Bullido MJ, Clarimón J, Hortigüela R, Frank-García A, Martínez-Martín P, Lleó A, Rey MJ, Sastre I, Rábano A, de Pedro-Cuesta J, Ferrer I, Calero M.

Prion. 2012 Sep-Oct;6(4):407-12. doi: 10.4161/pri.20785. Epub 2012 Aug 9.


Generation of Calhm1 knockout mouse and characterization of calhm1 gene expression.

Wu J, Peng S, Wu R, Hao Y, Ji G, Yuan Z.

Protein Cell. 2012 Jun;3(6):470-80. doi: 10.1007/s13238-012-2932-6. Epub 2012 Jun 21.


Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability.

Ma Z, Siebert AP, Cheung KH, Lee RJ, Johnson B, Cohen AS, Vingtdeux V, Marambaud P, Foskett JK.

Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):E1963-71. doi: 10.1073/pnas.1204023109. Epub 2012 Jun 18.

Supplemental Content

Loading ...
Support Center