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Best matches for alzheimer's bche:

Genetic underpinnings in Alzheimer's disease - a review. Moustafa AA et al. Rev Neurosci. (2018)

Butyrylcholinesterase as a Diagnostic and Therapeutic Target for Alzheimer's Disease. Darvesh S et al. Curr Alzheimer Res. (2016)

Cholinesterases in normal and Alzheimer's disease primary olfactory gyrus. Hamodat H et al. Neuropathol Appl Neurobiol. (2017)

Search results

Items: 1 to 20 of 461

1.

Inhibition of β-site amyloid precursor protein cleaving enzyme 1 and cholinesterases by pterosins via a specific structure-activity relationship with a strong BBB permeability.

Jannat S, Balupuri A, Ali MY, Hong SS, Choi CW, Choi YH, Ku JM, Kim WJ, Leem JY, Kim JE, Shrestha AC, Ham HN, Lee KH, Kim DM, Kang NS, Park GH.

Exp Mol Med. 2019 Feb 12;51(2):12. doi: 10.1038/s12276-019-0205-7.

PMID:
30755593
2.

Synthesis and biological activity of some benzochromenoquinolinones: Tacrine analogues as potent anti-Alzheimer's agents.

Mahdavi M, Hariri R, Mirfazli SS, Lotfian H, Rastergari A, Firuzi O, Edraki N, Larijani B, Akbarzadeh T, Saeedi M.

Chem Biodivers. 2019 Feb 5. doi: 10.1002/cbdv.201800488. [Epub ahead of print]

PMID:
30720917
3.

Mono- or di-substituted imidazole derivatives for inhibition of acetylcholine and butyrylcholine esterases.

Kuzu B, Tan M, Taslimi P, Gülçin İ, Taşpınar M, Menges N.

Bioorg Chem. 2019 Jan 24;86:187-196. doi: 10.1016/j.bioorg.2019.01.044. [Epub ahead of print]

PMID:
30711701
4.

Target Enzyme in Alzheimer's Disease:Acetylcholinesterase Inhibitors.

Saxena M, Dubey R.

Curr Top Med Chem. 2019 Jan 28. doi: 10.2174/1568026619666190128125912. [Epub ahead of print]

PMID:
30706815
5.

Diagnoses of pathological states based on acetylcholinesterase and butyrylcholinesterase.

Pohanka M.

Curr Med Chem. 2019 Jan 30. doi: 10.2174/0929867326666190130161202. [Epub ahead of print]

PMID:
30706778
6.

Pharmacophore-based drug design for the identification of novel butyrylcholinesterase inhibitors against Alzheimer's disease.

Jiang Y, Gao H.

Phytomedicine. 2018 Sep 18;54:278-290. doi: 10.1016/j.phymed.2018.09.199. [Epub ahead of print]

PMID:
30668379
7.

Synthesis and biological evaluation of novel tris-chalcones as potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and α-glycosidase inhibitors.

Burmaoglu S, Yilmaz AO, Polat MF, Kaya R, Gulcin İ, Algul O.

Bioorg Chem. 2019 Jan 2;85:191-197. doi: 10.1016/j.bioorg.2018.12.035. [Epub ahead of print]

PMID:
30622011
8.

Expansion of the scaffold diversity for the development of highly selective butyrylcholinesterase (BChE) inhibitors: Discovery of new hits through the pharmacophore model generation, virtual screening and molecular dynamics simulation.

Lu X, Yang H, Li Q, Chen Y, Li Q, Zhou Y, Feng F, Liu W, Guo Q, Sun H.

Bioorg Chem. 2018 Dec 21;85:117-127. doi: 10.1016/j.bioorg.2018.12.023. [Epub ahead of print]

PMID:
30605885
9.

Identify compounds's target against Alzheimer's disease based on silico approach.

Hu Y, Zhou G, Zhang C, Zhang M, Chen Q, Zheng L, Niu B.

Curr Alzheimer Res. 2019 Jan 3. doi: 10.2174/1567205016666190103154855. [Epub ahead of print]

PMID:
30605059
10.

Comprehensive review of mechanisms of pathogenesis involved in Alzheimer's disease and potential therapeutic strategies.

Sharma P, Srivastava P, Seth A, Tripathi PN, Banerjee AG, Shrivastava SK.

Prog Neurobiol. 2019 Mar;174:53-89. doi: 10.1016/j.pneurobio.2018.12.006. Epub 2018 Dec 30. Review.

PMID:
30599179
11.

HPLC-MS/MS chemical characterization and biological properties of Origanum onites extracts: a recent insight.

Mahomoodally MF, Zengin G, Aladag MO, Ozparlak H, Diuzheva A, Jekő J, Cziáky Z, Aumeeruddy MZ.

Int J Environ Health Res. 2018 Dec 20:1-15. doi: 10.1080/09603123.2018.1558184. [Epub ahead of print]

PMID:
30569760
12.

Multifunctional Donepezil Analogues as Cholinesterase and BACE1 Inhibitors.

Green KD, Fosso MY, Garneau-Tsodikova S.

Molecules. 2018 Dec 8;23(12). pii: E3252. doi: 10.3390/molecules23123252.

13.

In-vitro evaluation studies of 7-chloro-4-aminoquinoline Schiff bases and their copper complexes as cholinesterase inhibitors.

Zanon VS, Lima JA, Cuya T, Lima FRS, da Fonseca ACC, Gomez JG, Ribeiro RR, França TCC, Vargas MD.

J Inorg Biochem. 2019 Feb;191:183-193. doi: 10.1016/j.jinorgbio.2018.11.019. Epub 2018 Nov 30.

PMID:
30530179
14.

Combined molecular modeling and cholinesterase inhibition studies on some natural and semisynthetic O-alkylcoumarin derivatives.

Orhan IE, Senol Deniz FS, Salmas RE, Durdagi S, Epifano F, Genovese S, Fiorito S.

Bioorg Chem. 2019 Mar;84:355-362. doi: 10.1016/j.bioorg.2018.11.044. Epub 2018 Nov 26.

PMID:
30530106
15.

Contemporary medicinal-chemistry strategies for the discovery of selective butyrylcholinesterase inhibitors.

Jing L, Wu G, Kang D, Zhou Z, Song Y, Liu X, Zhan P.

Drug Discov Today. 2018 Nov 29. pii: S1359-6446(18)30333-7. doi: 10.1016/j.drudis.2018.11.012. [Epub ahead of print] Review.

PMID:
30503804
16.

Cholinesterase Inhibitory Activities of Selected Halogenated Thiophene Chalcones.

Parambi DGT, Aljoufi F, Murugaiyah V, Mathew GE, Dev S, Lakshminarayanan B, Hendawy OM, Mathew B.

Cent Nerv Syst Agents Med Chem. 2018 Nov 18. doi: 10.2174/1871524918666181119114016. [Epub ahead of print]

PMID:
30451121
17.

Assessment of novel azaanthraquinone derivatives as potent multi-target inhibitors of inflammation and amyloid-β aggregation in Alzheimer's disease.

Wang J, Li W, Qin J, Wang L, Wei S, Tang H.

Bioorg Chem. 2019 Mar;83:477-486. doi: 10.1016/j.bioorg.2018.10.073. Epub 2018 Nov 7.

PMID:
30448726
18.

Synthesis, preliminarily biological evaluation and molecular docking study of new Olaparib analogues as multifunctional PARP-1 and cholinesterase inhibitors.

Gao CZ, Dong W, Cui ZW, Yuan Q, Hu XM, Wu QM, Han X, Xu Y, Min ZL.

J Enzyme Inhib Med Chem. 2019 Dec;34(1):150-162. doi: 10.1080/14756366.2018.1530224.

19.

Novel tacrine-coumarin hybrids linked to 1,2,3-triazole as anti-Alzheimer's compounds: In vitro and in vivo biological evaluation and docking study.

Najafi Z, Mahdavi M, Saeedi M, Karimpour-Razkenari E, Edraki N, Sharifzadeh M, Khanavi M, Akbarzadeh T.

Bioorg Chem. 2019 Mar;83:303-316. doi: 10.1016/j.bioorg.2018.10.056. Epub 2018 Oct 28.

PMID:
30396115
20.

Molecular-docking-guided design and synthesis of new IAA-tacrine hybrids as multifunctional AChE/BChE inhibitors.

Cheng ZQ, Zhu KK, Zhang J, Song JL, Muehlmann LA, Jiang CS, Liu CL, Zhang H.

Bioorg Chem. 2019 Mar;83:277-288. doi: 10.1016/j.bioorg.2018.10.057. Epub 2018 Oct 29.

PMID:
30391700

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