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Items: 1 to 20 of 44

1.

Amyloid β Peptide Compromises Neural Stem Cell Fate by Irreversibly Disturbing Mitochondrial Oxidative State and Blocking Mitochondrial Biogenesis and Dynamics.

Ribeiro MF, Genebra T, Rego AC, Rodrigues CMP, Solá S.

Mol Neurobiol. 2018 Sep 18. doi: 10.1007/s12035-018-1342-z. [Epub ahead of print]

PMID:
30225776
2.

Mutant APP and amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimer's disease.

Reddy PH, Yin X, Manczak M, Kumar S, Pradeepkiran JA, Vijayan M, Reddy AP.

Hum Mol Genet. 2018 Jul 15;27(14):2502-2516. doi: 10.1093/hmg/ddy154.

PMID:
29701781
3.

Pattern recognition receptors mediate pro-inflammatory effects of extracellular mitochondrial transcription factor A (TFAM).

Schindler SM, Frank MG, Annis JL, Maier SF, Klegeris A.

Mol Cell Neurosci. 2018 Jun;89:71-79. doi: 10.1016/j.mcn.2018.04.005. Epub 2018 Apr 17.

PMID:
29678518
4.
5.

The mitochondrial transcription factor TFAM in neurodegeneration: emerging evidence and mechanisms.

Kang I, Chu CT, Kaufman BA.

FEBS Lett. 2018 Mar;592(5):793-811. doi: 10.1002/1873-3468.12989. Epub 2018 Feb 15. Review.

PMID:
29364506
6.

Inhibition of poly(ADP-ribose) polymerase-1 alters expression of mitochondria-related genes in PC12 cells: relevance to mitochondrial homeostasis in neurodegenerative disorders.

Czapski GA, Cieślik M, Wencel PL, Wójtowicz S, Strosznajder RP, Strosznajder JB.

Biochim Biophys Acta Mol Cell Res. 2018 Feb;1865(2):281-288. doi: 10.1016/j.bbamcr.2017.11.003. Epub 2017 Nov 8.

PMID:
29128369
7.

Cerebrospinal fluid neurofilament light chain as a biomarker of neurodegeneration in the Tg4510 and MitoPark mouse models.

Clement A, Mitchelmore C, Andersson DR, Asuni AA.

Neuroscience. 2017 Jun 23;354:101-109. doi: 10.1016/j.neuroscience.2017.04.030. Epub 2017 Apr 28.

PMID:
28461218
8.

Mitochondrial transcription factor A (TFAM) rs1937 and AP endonuclease 1 (APE1) rs1130409 alleles are associated with reduced cognitive performance.

Lillenes MS, Støen M, Günther CC, Selnes P, Stenset VT, Espeseth T, Reinvang I, Fladby T, Tønjum T.

Neurosci Lett. 2017 Apr 3;645:46-52. doi: 10.1016/j.neulet.2017.02.062. Epub 2017 Feb 24.

PMID:
28242328
9.

Reduced dynamin-related protein 1 protects against phosphorylated Tau-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.

Kandimalla R, Manczak M, Fry D, Suneetha Y, Sesaki H, Reddy PH.

Hum Mol Genet. 2016 Nov 15;25(22):4881-4897. doi: 10.1093/hmg/ddw312.

10.

Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer's disease.

Oka S, Leon J, Sakumi K, Ide T, Kang D, LaFerla FM, Nakabeppu Y.

Sci Rep. 2016 Nov 29;6:37889. doi: 10.1038/srep37889.

11.

Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.

Manczak M, Kandimalla R, Fry D, Sesaki H, Reddy PH.

Hum Mol Genet. 2016 Dec 1;25(23):5148-5166. doi: 10.1093/hmg/ddw330.

12.

Metformin activation of AMPK-dependent pathways is neuroprotective in human neural stem cells against Amyloid-beta-induced mitochondrial dysfunction.

Chiang MC, Cheng YC, Chen SJ, Yen CH, Huang RN.

Exp Cell Res. 2016 Oct 1;347(2):322-31. doi: 10.1016/j.yexcr.2016.08.013. Epub 2016 Aug 21.

PMID:
27554603
13.

Polymorphisms of CHAT but not TFAM or VR22 are Associated with Alzheimer Disease Risk.

Gao L, Zhang Y, Deng J, Yu W, Yu Y.

Med Sci Monit. 2016 Jun 7;22:1924-35.

14.

Rosiglitazone activation of PPARγ-dependent pathways is neuroprotective in human neural stem cells against amyloid-beta-induced mitochondrial dysfunction and oxidative stress.

Chiang MC, Nicol CJ, Cheng YC, Lin KH, Yen CH, Lin CH.

Neurobiol Aging. 2016 Apr;40:181-190. doi: 10.1016/j.neurobiolaging.2016.01.132. Epub 2016 Feb 27.

PMID:
26973118
15.

Neuroprotective Effect of Nanodiamond in Alzheimer's Disease Rat Model: a Pivotal Role for Modulating NF-κB and STAT3 Signaling.

Alawdi SH, El-Denshary ES, Safar MM, Eidi H, David MO, Abdel-Wahhab MA.

Mol Neurobiol. 2017 Apr;54(3):1906-1918. doi: 10.1007/s12035-016-9762-0. Epub 2016 Feb 20.

PMID:
26897372
16.

Mitochondrial Alterations in Peripheral Mononuclear Blood Cells from Alzheimer's Disease and Mild Cognitive Impairment Patients.

Delbarba A, Abate G, Prandelli C, Marziano M, Buizza L, Arce Varas N, Novelli A, Cuetos F, Martinez C, Lanni C, Memo M, Uberti D.

Oxid Med Cell Longev. 2016;2016:5923938. doi: 10.1155/2016/5923938. Epub 2016 Jan 6.

17.

Lower Prevalence of Alzheimer's Disease among Tibetans: Association with Religious and Genetic Factors.

Huang F, Shang Y, Luo Y, Wu P, Huang X, Tan X, Lu X, Zhen L, Hu X.

J Alzheimers Dis. 2016;50(3):659-67. doi: 10.3233/JAD-150697.

PMID:
26757186
18.

Mitochondrial retrograde signaling regulates neuronal function.

Cagin U, Duncan OF, Gatt AP, Dionne MS, Sweeney ST, Bateman JM.

Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):E6000-9. doi: 10.1073/pnas.1505036112. Epub 2015 Oct 21. Erratum in: Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):E7032.

19.

Aβ25-35 Suppresses Mitochondrial Biogenesis in Primary Hippocampal Neurons.

Dong W, Wang F, Guo W, Zheng X, Chen Y, Zhang W, Shi H.

Cell Mol Neurobiol. 2016 Jan;36(1):83-91. doi: 10.1007/s10571-015-0222-6. Epub 2015 Jun 9.

PMID:
26055049
20.

Beneficial Effect of Flavone Derivatives on Aβ-Induced Memory Deficit Is Mediated by Peroxisome Proliferator-Activated Receptor γ Coactivator 1α: A Comparative Study.

Arsalandeh F, Ahmadian S, Foolad F, Khodagholi F, Farimani MM, Shaerzadeh F.

Int J Toxicol. 2015 May-Jun;34(3):274-83. doi: 10.1177/1091581815584165. Epub 2015 May 13.

PMID:
25972379

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