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Items: 1 to 20 of 41

1.

Aldehyde dehydrogenase 2 in the spotlight: The link between mitochondria and neurodegeneration.

Deza-Ponzio R, Herrera ML, Bellini MJ, Virgolini MB, Hereñú CB.

Neurotoxicology. 2018 Sep;68:19-24. doi: 10.1016/j.neuro.2018.06.005. Epub 2018 Jun 21.

PMID:
29936317
2.

Effects of "Essential AD2" Supplement on Blood Acetaldehyde Levels in Individuals Who Have Aldehyde Dehydrogenase (ALDH2) Deficiency.

Fujioka K, Gordon S.

Am J Ther. 2018 Feb 21. doi: 10.1097/MJT.0000000000000744. [Epub ahead of print]

PMID:
29509552
3.

Formaldehyde induces diabetes-associated cognitive impairments.

Tan T, Zhang Y, Luo W, Lv J, Han C, Hamlin JNR, Luo H, Li H, Wan Y, Yang X, Song W, Tong Z.

FASEB J. 2018 Jul;32(7):3669-3679. doi: 10.1096/fj.201701239R. Epub 2018 Feb 1.

PMID:
29401634
4.

The Antioxidant Cofactor Alpha-Lipoic Acid May Control Endogenous Formaldehyde Metabolism in Mammals.

Shindyapina AV, Komarova TV, Sheshukova EV, Ershova NM, Tashlitsky VN, Kurkin AV, Yusupov IR, Mkrtchyan GV, Shagidulin MY, Dorokhov YL.

Front Neurosci. 2017 Dec 1;11:651. doi: 10.3389/fnins.2017.00651. eCollection 2017.

5.

Deuterium-reinforced polyunsaturated fatty acids improve cognition in a mouse model of sporadic Alzheimer's disease.

Elharram A, Czegledy NM, Golod M, Milne GL, Pollock E, Bennett BM, Shchepinov MS.

FEBS J. 2017 Dec;284(23):4083-4095. doi: 10.1111/febs.14291. Epub 2017 Oct 27.

PMID:
29024570
6.

In vivo imaging of prodromal hippocampus CA1 subfield oxidative stress in models of Alzheimer disease and Angelman syndrome.

Berkowitz BA, Lenning J, Khetarpal N, Tran C, Wu JY, Berri AM, Dernay K, Haacke EM, Shafie-Khorassani F, Podolsky RH, Gant JC, Maimaiti S, Thibault O, Murphy GG, Bennett BM, Roberts R.

FASEB J. 2017 Sep;31(9):4179-4186. doi: 10.1096/fj.201700229R. Epub 2017 Jun 7.

PMID:
28592637
7.

Effects of the common polymorphism in the human aldehyde dehydrogenase 2 (ALDH2) gene on the lung.

Kuroda A, Hegab AE, Jingtao G, Yamashita S, Hizawa N, Sakamoto T, Yamada H, Suzuki S, Ishii M, Namkoong H, Asakura T, Ozaki M, Yasuda H, Hamamoto J, Kagawa S, Soejima K, Betsuyaku T.

Respir Res. 2017 Apr 21;18(1):69. doi: 10.1186/s12931-017-0554-5.

8.

The Role of Mitochondrial Aldehyde Dehydrogenase 2 (ALDH2) in Neuropathology and Neurodegeneration.

Chen CH, Joshi AU, Mochly-Rosen D.

Acta Neurol Taiwan. 2016 Dec 15;25(4):111-123. Review.

9.

Proteomic Analysis of Mitochondria-Enriched Fraction Isolated from the Frontal Cortex and Hippocampus of Apolipoprotein E Knockout Mice Treated with Alda-1, an Activator of Mitochondrial Aldehyde Dehydrogenase (ALDH2).

Stachowicz A, Olszanecki R, Suski M, Głombik K, Basta-Kaim A, Adamek D, Korbut R.

Int J Mol Sci. 2017 Feb 17;18(2). pii: E435. doi: 10.3390/ijms18020435.

10.

Hydrogen Sulfide Ameliorates Homocysteine-Induced Cognitive Dysfunction by Inhibition of Reactive Aldehydes Involving Upregulation of ALDH2.

Li M, Zhang P, Wei HJ, Li MH, Zou W, Li X, Gu HF, Tang XQ.

Int J Neuropsychopharmacol. 2017 Apr 1;20(4):305-315. doi: 10.1093/ijnp/pyw103.

11.

Role of ADH1B rs1229984 and ALDH2 rs671 gene polymorphisms in the development of Alzheimer's disease.

Ma L, Lu ZN.

Genet Mol Res. 2016 Oct 5;15(4). doi: 10.4238/gmr.15048740.

PMID:
27808372
12.

A multifunctional therapeutic approach to disease modification in multiple familial mouse models and a novel sporadic model of Alzheimer's disease.

Luo J, Lee SH, VandeVrede L, Qin Z, Ben Aissa M, Larson J, Teich AF, Arancio O, D'Souza Y, Elharram A, Koster K, Tai LM, LaDu MJ, Bennett BM, Thatcher GR.

Mol Neurodegener. 2016 Apr 29;11:35. doi: 10.1186/s13024-016-0103-6. Erratum in: Mol Neurodegener. 2016;11(1):40.

13.

Epigenetic mechanisms underlying cognitive impairment and Alzheimer disease hallmarks in 5XFAD mice.

Griñán-Ferré C, Sarroca S, Ivanova A, Puigoriol-Illamola D, Aguado F, Camins A, Sanfeliu C, Pallàs M.

Aging (Albany NY). 2016 Apr;8(4):664-84. doi: 10.18632/aging.100906.

14.

Glu504Lys Single Nucleotide Polymorphism of Aldehyde Dehydrogenase 2 Gene and the Risk of Human Diseases.

Zhao Y, Wang C.

Biomed Res Int. 2015;2015:174050. doi: 10.1155/2015/174050. Epub 2015 Sep 27. Review.

15.

Characterization of Aldh2 (-/-) mice as an age-related model of cognitive impairment and Alzheimer's disease.

D'Souza Y, Elharram A, Soon-Shiong R, Andrew RD, Bennett BM.

Mol Brain. 2015 Apr 25;8:27. doi: 10.1186/s13041-015-0117-y.

16.

Oxidative stress accelerates amyloid deposition and memory impairment in a double-transgenic mouse model of Alzheimer's disease.

Kanamaru T, Kamimura N, Yokota T, Iuchi K, Nishimaki K, Takami S, Akashiba H, Shitaka Y, Katsura K, Kimura K, Ohta S.

Neurosci Lett. 2015 Feb 5;587:126-31. doi: 10.1016/j.neulet.2014.12.033. Epub 2014 Dec 18.

PMID:
25529196
17.

Protective effects of ferulic acid and related polyphenols against glyoxal- or methylglyoxal-induced cytotoxicity and oxidative stress in isolated rat hepatocytes.

Maruf AA, Lip H, Wong H, O'Brien PJ.

Chem Biol Interact. 2015 Jun 5;234:96-104. doi: 10.1016/j.cbi.2014.11.007. Epub 2014 Nov 18.

PMID:
25446858
18.

Aldehyde dehydrogenase (ALDH) in Alzheimer's and Parkinson's disease.

Grünblatt E, Riederer P.

J Neural Transm (Vienna). 2016 Feb;123(2):83-90. doi: 10.1007/s00702-014-1320-1. Epub 2014 Oct 9. Review.

PMID:
25298080
19.

A novel mechanism for endogenous formaldehyde elevation in SAMP8 mouse.

Qiang M, Xiao R, Su T, Wu BB, Tong ZQ, Liu Y, He RQ.

J Alzheimers Dis. 2014;40(4):1039-53. doi: 10.3233/JAD-131595.

PMID:
24583407
20.

Polymorphisms in the aldehyde dehydrogenase 2 and dopamine β hydroxylase genes are not associated with Alzheimer's disease.

Komatsu M, Shibata N, Ohnuma T, Kuerban B, Tomson K, Toda A, Tagata Y, Nakada T, Shimazaki H, Arai H.

J Neural Transm (Vienna). 2014 Apr;121(4):427-32. doi: 10.1007/s00702-013-1112-z. Epub 2013 Nov 8.

PMID:
24201835

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