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Items: 1 to 20 of 143

1.

More expansive gene transfer to the rat CNS: AAV PHP.EB vector dose-response and comparison to AAV PHP.B.

Dayton RD, Grames MS, Klein RL.

Gene Ther. 2018 Jul 16. doi: 10.1038/s41434-018-0028-5. [Epub ahead of print]

PMID:
30013186
2.

FTO-Dependent m6A Regulates Cardiac Function During Remodeling and Repair.

Mathiyalagan P, Adamiak M, Mayourian J, Sassi Y, Liang Y, Agarwal N, Jha D, Zhang S, Kohlbrenner E, Chepurko E, Chen J, Trivieri MG, Singh R, Bouchareb R, Fish K, Ishikawa K, Lebeche D, Hajjar RJ, Sahoo S.

Circulation. 2018 Jul 11. pii: CIRCULATIONAHA.118.033794. doi: 10.1161/CIRCULATIONAHA.118.033794. [Epub ahead of print]

PMID:
29997116
3.

Aldolase promotes the development of cardiac hypertrophy by targeting AMPK signaling.

Li Y, Zhang D, Kong L, Shi H, Tian X, Gao L, Liu Y, Wu L, Du B, Huang Z, Liang C, Wang Z, Yao R, Zhang Y.

Exp Cell Res. 2018 Jun 11. pii: S0014-4827(18)30339-2. doi: 10.1016/j.yexcr.2018.06.009. [Epub ahead of print]

PMID:
29902536
4.

Systemic delivery of AAVB1-GAA clears glycogen and prolongs survival in a mouse model of Pompe disease.

Keeler AM, Zieger M, Todeasa S, Mccall A, Gifford J, Bircsak S, Choudhury SR, Byrne BJ, Sena-Esteves M, ElMallah MK.

Hum Gene Ther. 2018 Jun 14. doi: 10.1089/hum.2018.016. [Epub ahead of print]

PMID:
29901418
5.

Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation.

Yao C, Veleva T, Scott L Jr, Cao S, Li L, Chen G, Jeyabal P, Pan X, Alsina KM, Abu-Taha I, Ghezelbash S, Reynolds CL, Shen YH, LeMaire SA, Schmitz W, Müller FU, El-Armouche A, Eissa NT, Beeton C, Nattel S, Wehrens XHT, Dobrev D, Li N.

Circulation. 2018 May 25. pii: CIRCULATIONAHA.118.035202. doi: 10.1161/CIRCULATIONAHA.118.035202. [Epub ahead of print]

PMID:
29802206
6.

Cardiac Ablation of SOCS3 Aggravates DOCA-Salt-Induced Hypertrophic Remodeling by Activation of Gp130-Dependent Signaling in Mice.

Liu S, Liu LX, Zhang YL, Lai S, Xie YP, Li NN, Wang HX, Xia YL, Liu Y, Li HH.

Cell Physiol Biochem. 2018;47(1):140-150. doi: 10.1159/000489757. Epub 2018 May 10.

7.

A Simple and Efficient Method for In Vivo Cardiac-specific Gene Manipulation by Intramyocardial Injection in Mice.

Fu Y, Jiang W, Zhao Y, Huang Y, Zhang H, Wang H, Pu J.

J Vis Exp. 2018 Apr 16;(134). doi: 10.3791/57074.

PMID:
29708533
8.

MicroRNA-223 Regulates Cardiac Fibrosis After Myocardial Infarction by Targeting RASA1.

Liu X, Xu Y, Deng Y, Li H.

Cell Physiol Biochem. 2018;46(4):1439-1454. doi: 10.1159/000489185. Epub 2018 Apr 19.

9.

Rearrangement of the Protein Phosphatase 1 Interactome During Heart Failure Progression.

Chiang DY, Alsina KM, Corradini E, Fitzpatrick M, Ni L, Lahiri SK, Reynolds J, Pan X, Scott L Jr, Heck AJR, Wehrens XH.

Circulation. 2018 Apr 18. pii: CIRCULATIONAHA.118.034361. doi: 10.1161/CIRCULATIONAHA.118.034361. [Epub ahead of print]

PMID:
29669786
10.

A Calsequestrin Cis-Regulatory Motif Coupled to a Cardiac Troponin T Promoter Improves Cardiac Adeno-Associated Virus Serotype 9 Transduction Specificity.

Chamberlain K, Riyad JM, Garnett T, Kohlbrenner E, Mookerjee A, Elmastour F, Benard L, Chen J, VandenDriessche T, Chuah MK, Marian AJ, Hajjar RJ, Gurha P, Weber T.

Hum Gene Ther. 2018 May 9. doi: 10.1089/hum.2017.188. [Epub ahead of print]

PMID:
29641321
11.

Non-invasive detection of adeno-associated viral gene transfer using a genetically encoded CEST-MRI reporter gene in the murine heart.

Meier S, Gilad AA, Brandon JA, Qian C, Gao E, Abisambra JF, Vandsburger M.

Sci Rep. 2018 Mar 15;8(1):4638. doi: 10.1038/s41598-018-22993-4.

12.

Overexpression of prostaglandin E2 EP4 receptor improves cardiac function after myocardial infarction.

Bryson TD, Gu X, Khalil RM, Khan S, Zhu L, Xu J, Peterson E, Yang XP, Harding P.

J Mol Cell Cardiol. 2018 May;118:1-12. doi: 10.1016/j.yjmcc.2018.03.005. Epub 2018 Mar 6.

PMID:
29522761
13.

Cardiac adenovirus-associated viral Presenilin 1 gene delivery protects the left ventricular function of the heart via regulating RyR2 function in post-ischaemic heart failure.

Li T, Shen Y, Su L, Fan X, Lin F, Ye X, Ding D, Tang Y, Yang Y, Lei C, Hu S.

J Drug Target. 2018 Mar 21:1-10. doi: 10.1080/1061186X.2018.1450412. [Epub ahead of print]

PMID:
29521549
14.

Targeting ALDH2 for Therapeutic Interventions in Chronic Pain-Related Myocardial Ischemic Susceptibility.

Li C, Sun W, Gu C, Yang Z, Quan N, Yang J, Shi Z, Yu L, Ma H.

Theranostics. 2018 Jan 1;8(4):1027-1041. doi: 10.7150/thno.22414. eCollection 2018.

15.

HuR-mediated SCN5A messenger RNA stability reduces arrhythmic risk in heart failure.

Zhou A, Xie A, Kim TY, Liu H, Shi G, Kang GJ, Jiang N, Liu M, Jeong EM, Choi BR, Dudley SC Jr.

Heart Rhythm. 2018 Jul;15(7):1072-1080. doi: 10.1016/j.hrthm.2018.02.018. Epub 2018 Feb 16.

PMID:
29454929
16.

The protective effect of nicorandil on cardiomyocyte apoptosis after coronary microembolization by activating Nrf2/HO-1 signaling pathway in rats.

He W, Su Q, Liang J, Sun Y, Wang X, Li L.

Biochem Biophys Res Commun. 2018 Feb 19;496(4):1296-1301. doi: 10.1016/j.bbrc.2018.02.003. Epub 2018 Feb 3.

PMID:
29412163
17.

Cardiomyocyte-specific deletion of Sirt1 gene sensitizes myocardium to ischaemia and reperfusion injury.

Wang L, Quan N, Sun W, Chen X, Cates C, Rousselle T, Zhou X, Zhao X, Li J.

Cardiovasc Res. 2018 May 1;114(6):805-821. doi: 10.1093/cvr/cvy033.

PMID:
29409011
18.

AAV-9 mediated phosphatase-1 inhibitor-1 overexpression improves cardiac contractility in unchallenged mice but is deleterious in pressure-overload.

Schwab DM, Tilemann L, Bauer R, Heckmann M, Jungmann A, Wagner M, Burgis J, Vettel C, Katus HA, El-Armouche A, Müller OJ.

Gene Ther. 2018 Jan;25(1):13-19. doi: 10.1038/gt.2017.97. Epub 2018 Jan 19.

PMID:
29350681
19.

Sestrin2 prevents age-related intolerance to post myocardial infarction via AMPK/PGC-1α pathway.

Quan N, Wang L, Chen X, Luckett C, Cates C, Rousselle T, Zheng Y, Li J.

J Mol Cell Cardiol. 2018 Feb;115:170-178. doi: 10.1016/j.yjmcc.2018.01.005. Epub 2018 Jan 8.

20.

miR-25 Tough Decoy Enhances Cardiac Function in Heart Failure.

Jeong D, Yoo J, Lee P, Kepreotis SV, Lee A, Wahlquist C, Brown BD, Kho C, Mercola M, Hajjar RJ.

Mol Ther. 2018 Mar 7;26(3):718-729. doi: 10.1016/j.ymthe.2017.11.014. Epub 2017 Nov 26.

PMID:
29273502

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