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Items: 14


Modeling Tumor Clonal Evolution for Drug Combinations Design.

Zhao B, Hemann MT, Lauffenburger DA.

Trends Cancer. 2016 Mar;2(3):144-158. doi: 10.1016/j.trecan.2016.02.001. Review.


Differential selective pressure alters rate of drug resistance acquisition in heterogeneous tumor populations.

Sun D, Dalin S, Hemann MT, Lauffenburger DA, Zhao B.

Sci Rep. 2016 Nov 7;6:36198. doi: 10.1038/srep36198.


Inherited Disease Genetics Improves the Identification of Cancer-Associated Genes.

Zhao B, Pritchard JR.

PLoS Genet. 2016 Jun 15;12(6):e1006081. doi: 10.1371/journal.pgen.1006081. eCollection 2016 Jun.


Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution.

Zhao B, Sedlak JC, Srinivas R, Creixell P, Pritchard JR, Tidor B, Lauffenburger DA, Hemann MT.

Cell. 2016 Mar 24;165(1):234-246. doi: 10.1016/j.cell.2016.01.045. Epub 2016 Feb 25.


Acquisition of a single EZH2 D1 domain mutation confers acquired resistance to EZH2-targeted inhibitors.

Baker T, Nerle S, Pritchard J, Zhao B, Rivera VM, Garner A, Gonzalvez F.

Oncotarget. 2015 Oct 20;6(32):32646-55. doi: 10.18632/oncotarget.5066.


Reply to Azuaje: Predicting effective combined therapies for heterogeneous tumors.

Zhao B, Hemann MT, Lauffenburger DA.

Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):E4288. doi: 10.1073/pnas.1415737111. Epub 2014 Sep 24. No abstract available.


Intratumor heterogeneity alters most effective drugs in designed combinations.

Zhao B, Hemann MT, Lauffenburger DA.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10773-8. doi: 10.1073/pnas.1323934111. Epub 2014 Jul 7.


Addressing genetic tumor heterogeneity through computationally predictive combination therapy.

Zhao B, Pritchard JR, Lauffenburger DA, Hemann MT.

Cancer Discov. 2014 Feb;4(2):166-74. doi: 10.1158/2159-8290.CD-13-0465. Epub 2013 Dec 6.


Updates on the web-based VIOLIN vaccine database and analysis system.

He Y, Racz R, Sayers S, Lin Y, Todd T, Hur J, Li X, Patel M, Zhao B, Chung M, Ostrow J, Sylora A, Dungarani P, Ulysse G, Kochhar K, Vidri B, Strait K, Jourdian GW, Xiang Z.

Nucleic Acids Res. 2014 Jan;42(Database issue):D1124-32. doi: 10.1093/nar/gkt1133. Epub 2013 Nov 19.


CPhos: a program to calculate and visualize evolutionarily conserved functional phosphorylation sites.

Zhao B, Pisitkun T, Hoffert JD, Knepper MA, Saeed F.

Proteomics. 2012 Nov;12(22):3299-303. doi: 10.1002/pmic.201200189. Epub 2012 Oct 29.


Large-scale phosphotyrosine proteomic profiling of rat renal collecting duct epithelium reveals predominance of proteins involved in cell polarity determination.

Zhao B, Knepper MA, Chou CL, Pisitkun T.

Am J Physiol Cell Physiol. 2012 Jan 1;302(1):C27-45. doi: 10.1152/ajpcell.00300.2011. Epub 2011 Sep 21.


Kinetic mechanism for the excision of hypoxanthine by Escherichia coli AlkA and evidence for binding to DNA ends.

Zhao B, O'Brien PJ.

Biochemistry. 2011 May 24;50(20):4350-9. doi: 10.1021/bi200232c. Epub 2011 Apr 28.


Large-scale phosphoproteomic analysis of membrane proteins in renal proximal and distal tubule.

Feric M, Zhao B, Hoffert JD, Pisitkun T, Knepper MA.

Am J Physiol Cell Physiol. 2011 Apr;300(4):C755-70. doi: 10.1152/ajpcell.00360.2010. Epub 2011 Jan 5.


VIOLIN: vaccine investigation and online information network.

Xiang Z, Todd T, Ku KP, Kovacic BL, Larson CB, Chen F, Hodges AP, Tian Y, Olenzek EA, Zhao B, Colby LA, Rush HG, Gilsdorf JR, Jourdian GW, He Y.

Nucleic Acids Res. 2008 Jan;36(Database issue):D923-8. Epub 2007 Nov 19.

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