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Items: 1 to 20 of 173

1.

The disparate twins: a comparative study of CXCR4 and CXCR7 in SDF-1α-induced gene expression, invasion and chemosensitivity of colon cancer.

Heckmann D, Maier P, Laufs S, Li L, Sleeman JP, Trunk MJ, Leupold JH, Wenz F, Zeller WJ, Fruehauf S, Allgayer H.

Clin Cancer Res. 2014 Feb 1;20(3):604-16. doi: 10.1158/1078-0432.CCR-13-0582. Epub 2013 Nov 19.

2.

CXCR4 Expression and Treatment with SDF-1α or Plerixafor Modulate Proliferation and Chemosensitivity of Colon Cancer Cells.

Heckmann D, Maier P, Laufs S, Wenz F, Zeller WJ, Fruehauf S, Allgayer H.

Transl Oncol. 2013 Apr;6(2):124-32. Epub 2013 Apr 1.

3.

F2A sequence linking MGMT(P140K) and MDR1 in a bicistronic lentiviral vector enables efficient chemoprotection of haematopoietic stem cells.

Maier P, Heckmann D, Spier I, Laufs S, Zucknick M, Allgayer H, Fruehauf S, Zeller WJ, Wenz F.

Cancer Gene Ther. 2012 Nov;19(11):802-10. doi: 10.1038/cgt.2012.67. Epub 2012 Oct 5.

PMID:
23037811
4.

A Lentiviral CXCR4 overexpression and knockdown model in colorectal cancer cell lines reveals plerixafor-dependent suppression of SDF-1α-induced migration and invasion.

Heckmann D, Laufs S, Maier P, Zucknick M, Giordano FA, Veldwijk MR, Eckstein V, Wenz F, Zeller WJ, Fruehauf S, Allgayer H.

Onkologie. 2011;34(10):502-8. doi: 10.1159/000332390. Epub 2011 Sep 20.

PMID:
21985848
5.

Overexpression of manganese superoxide dismutase does not increase clonogenic cell survival despite effect on apoptosis in irradiated lymphoblastoid cells.

Veldwijk MR, Trah J, Wang M, Maier P, Fruehauf S, Zeller WJ, Herskind C, Wenz F.

Radiat Res. 2011 Dec;176(6):725-31. Epub 2011 Oct 4.

PMID:
21899432
6.

Efficient gene transfer with pseudotyped recombinant adeno-associated viral vectors into human chronic myelogenous leukemia cells.

Sellner L, Veldwijk MR, Kleinschmidt JA, Laufs S, Topaly J, Fruehauf S, Zeller WJ, Wenz F.

Leuk Lymphoma. 2011 Mar;52(3):483-90. doi: 10.3109/10428194.2010.545460.

PMID:
21323526
7.

Clonal inventory screens uncover monoclonality following serial transplantation of MGMT P140K-transduced stem cells and dose-intense chemotherapy.

Giordano FA, Sorg UR, Appelt JU, Lachmann N, Bleier S, Roeder I, Kleff V, Flasshove M, Zeller WJ, Allgayer H, von Kalle C, Fruehauf S, Moritz T, Laufs S.

Hum Gene Ther. 2011 Jun;22(6):697-710. doi: 10.1089/hum.2010.088. Epub 2011 Apr 11.

PMID:
21319998
8.

Unrestricted somatic stem cells: interaction with CD34+ cells in vitro and in vivo, expression of homing genes and exclusion of tumorigenic potential.

Jeltsch KS, Radke TF, Laufs S, Giordano FA, Allgayer H, Wenz F, Zeller WJ, Kögler G, Fruehauf S, Maier P.

Cytotherapy. 2011 Mar;13(3):357-65. doi: 10.3109/14653249.2010.523076. Epub 2010 Oct 18.

PMID:
20950214
9.

SNAI2 as a novel radioprotector of normal tissue by gene transfer using a lentiviral bicistronic SIN vector.

Maier P, Herskind C, Barzan D, Zeller WJ, Wenz F.

Radiat Res. 2010 May;173(5):612-9. doi: 10.1667/RR1952.1.

PMID:
20426660
10.

Good manufacturing practice-grade production of unrestricted somatic stem cell from fresh cord blood.

Aktas M, Buchheiser A, Houben A, Reimann V, Radke T, Jeltsch K, Maier P, Zeller WJ, Kogler G.

Cytotherapy. 2010 May;12(3):338-48. doi: 10.3109/14653241003695034.

PMID:
20370349
11.

Analysis of self-inactivating lentiviral vector integration sites and flanking gene expression in human peripheral blood progenitor cells after alkylator chemotherapy.

Grund N, Maier P, Giordano FA, Appelt JU, Zucknick M, Li L, Wenz F, Zeller WJ, Fruehauf S, Allgayer H, Laufs S.

Hum Gene Ther. 2010 Aug;21(8):943-56. doi: 10.1089/hum.2009.116.

PMID:
20210626
12.

Overexpression of caveolin-1 in lymphoblastoid TK6 cells enhances proliferation after irradiation with clinically relevant doses.

Barzan D, Maier P, Zeller WJ, Wenz F, Herskind C.

Strahlenther Onkol. 2010 Feb;186(2):99-106. doi: 10.1007/s00066-010-2029-1. Epub 2010 Jan 28.

PMID:
20127227
13.

Unrestricted somatic stem cells support HSC proliferation in vitro and engraftment in vivo and possess no tumorigenic potential.

Jeltsch K, Radke T, Laufs S, Giordano F, Allgayer H, Wenz F, Zeller WJ, Kögler G, Maier P.

J Stem Cells Regen Med. 2010 Oct 23;6(2):113-4. eCollection 2010. No abstract available.

PMID:
24693127
14.

Pseudotyped recombinant adeno-associated viral vectors mediate efficient gene transfer into primary human CD34(+) peripheral blood progenitor cells.

Veldwijk MR, Sellner L, Stiefelhagen M, Kleinschmidt JA, Laufs S, Topaly J, Fruehauf S, Zeller WJ, Wenz F.

Cytotherapy. 2010;12(1):107-12. doi: 10.3109/14653240903348293.

PMID:
19929455
15.

Chemoprotection of human hematopoietic stem cells by simultaneous lentiviral overexpression of multidrug resistance 1 and O(6)-methylguanine-DNA methyltransferase(P140K).

Maier P, Spier I, Laufs S, Veldwijk MR, Fruehauf S, Wenz F, Zeller WJ.

Gene Ther. 2010 Mar;17(3):389-99. doi: 10.1038/gt.2009.133. Epub 2009 Oct 29.

PMID:
19865182
16.

Synergistic activity of nilotinib and established chemotherapeutic drugs in imatinib-sensitive and -resistant BCR-ABL-positive cells.

Radujkovic A, Fruehauf S, Zeller WJ, Ho AD, Topaly J.

Cancer Chemother Pharmacol. 2010 Jul;66(2):255-64. doi: 10.1007/s00280-009-1158-7. Epub 2009 Oct 28.

PMID:
19862526
17.

Cold spots in hot spots: transcription start sites of active genes are spared from HIV vector integration.

Giordano FA, Appelt JU, Zucknick M, Abba M, Zeller WJ, Fruehauf S, Allgayer H, Laufs S.

AIDS. 2009 Nov 27;23(18):2535-7. doi: 10.1097/QAD.0b013e3283336432.

PMID:
19841571
18.

Normal-tissue radioprotection by overexpression of the copper-zinc and manganese superoxide dismutase genes.

Veldwijk MR, Herskind C, Sellner L, Radujkovic A, Laufs S, Fruehauf S, Zeller WJ, Wenz F.

Strahlenther Onkol. 2009 Aug;185(8):517-23. doi: 10.1007/s00066-009-1973-0. Epub 2009 Aug 4.

PMID:
19652935
19.

QuickMap: a public tool for large-scale gene therapy vector insertion site mapping and analysis.

Appelt JU, Giordano FA, Ecker M, Roeder I, Grund N, Hotz-Wagenblatt A, Opelz G, Zeller WJ, Allgayer H, Fruehauf S, Laufs S.

Gene Ther. 2009 Jul;16(7):885-93. doi: 10.1038/gt.2009.37. Epub 2009 Apr 23.

PMID:
19387483
20.

Application of a haematopoetic progenitor cell-targeted adeno-associated viral (AAV) vector established by selection of an AAV random peptide library on a leukaemia cell line.

Stiefelhagen M, Sellner L, Kleinschmidt JA, Jauch A, Laufs S, Wenz F, Zeller WJ, Fruehauf S, Veldwijk MR.

Genet Vaccines Ther. 2008 Sep 12;6:12. doi: 10.1186/1479-0556-6-12.

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