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Items: 17


Cohen's h for detection of disease association with rare genetic variants.

Wen SH, Yeh JI.

BMC Genomics. 2014 Oct 8;15:875. doi: 10.1186/1471-2164-15-875.


Interaction with the Src homology (SH3-SH2) region of the Src-family kinase Hck structures the HIV-1 Nef dimer for kinase activation and effector recruitment.

Alvarado JJ, Tarafdar S, Yeh JI, Smithgall TE.

J Biol Chem. 2014 Oct 10;289(41):28539-53. doi: 10.1074/jbc.M114.600031.


Effector kinase coupling enables high-throughput screens for direct HIV-1 Nef antagonists with antiretroviral activity.

Emert-Sedlak LA, Narute P, Shu ST, Poe JA, Shi H, Yanamala N, Alvarado JJ, Lazo JS, Yeh JI, Johnston PA, Smithgall TE.

Chem Biol. 2013 Jan 24;20(1):82-91. doi: 10.1016/j.chembiol.2012.11.005.


Prolonged induction activates Cebpα independent adipogenesis in NIH/3T3 cells.

Shao HY, Hsu HY, Wu KS, Hee SW, Chuang LM, Yeh JI.

PLoS One. 2013;8(1):e51459. doi: 10.1371/journal.pone.0051459.


Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair.

Yeh JI, Levine AS, Du S, Chinte U, Ghodke H, Wang H, Shi H, Hsieh CL, Conway JF, Van Houten B, Rapić-Otrin V.

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):E2737-46. doi: 10.1073/pnas.1110067109.


First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy.

Sen M, Thomas SM, Kim S, Yeh JI, Ferris RL, Johnson JT, Duvvuri U, Lee J, Sahu N, Joyce S, Freilino ML, Shi H, Li C, Ly D, Rapireddy S, Etter JP, Li PK, Wang L, Chiosea S, Seethala RR, Gooding WE, Chen X, Kaminski N, Pandit K, Johnson DE, Grandis JR.

Cancer Discov. 2012 Aug;2(8):694-705. doi: 10.1158/2159-8290.CD-12-0191.


Interaction of haptoglobin with hemoglobin octamers based on the mutation αAsn78Cys or βGly83Cys.

Brillet T, Marden MC, Yeh JI, Shen TJ, Ho NT, Kettering R, Du S, Vasseur C, Domingues-Hamdi E, Ho C, Baudin-Creuza V.

Am J Mol Biol. 2012 Apr 1;2(1):1-10.


HIV-1 Nef interaction influences the ATP-binding site of the Src-family kinase, Hck.

Pene-Dumitrescu T, Shu ST, Wales TE, Alvarado JJ, Shi H, Narute P, Moroco JA, Yeh JI, Engen JR, Smithgall TE.

BMC Chem Biol. 2012 Mar 15;12:1. doi: 10.1186/1472-6769-12-1.


Structure of the HIV-1 full-length capsid protein in a conformationally trapped unassembled state induced by small-molecule binding.

Du S, Betts L, Yang R, Shi H, Concel J, Ahn J, Aiken C, Zhang P, Yeh JI.

J Mol Biol. 2011 Feb 25;406(3):371-86. doi: 10.1016/j.jmb.2010.11.027.


The crystal structure of non-modified and bipyridine-modified PNA duplexes.

Yeh JI, Pohl E, Truan D, He W, Sheldrick GM, Du S, Achim C.

Chemistry. 2010 Oct 18;16(39):11867-75. doi: 10.1002/chem.201000392. Erratum in: Chemistry. 2011 Oct 24;17(44):12227.


Crystal structure of the Src family kinase Hck SH3-SH2 linker regulatory region supports an SH3-dominant activation mechanism.

Alvarado JJ, Betts L, Moroco JA, Smithgall TE, Yeh JI.

J Biol Chem. 2010 Nov 12;285(46):35455-61. doi: 10.1074/jbc.M110.145102.


Crystal structure of chiral gammaPNA with complementary DNA strand: insights into the stability and specificity of recognition and conformational preorganization.

Yeh JI, Shivachev B, Rapireddy S, Crawford MJ, Gil RR, Du S, Madrid M, Ly DH.

J Am Chem Soc. 2010 Aug 11;132(31):10717-27. doi: 10.1021/ja907225d.


Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties.

Xia T, Kovochich M, Liong M, Mädler L, Gilbert B, Shi H, Yeh JI, Zink JI, Nel AE.

ACS Nano. 2008 Oct 28;2(10):2121-34. doi: 10.1021/nn800511k. Erratum in: ACS Nano. 2008 Dec 23;2(12):2592.


Structural characterizations of glycerol kinase: unraveling phosphorylation-induced long-range activation.

Yeh JI, Kettering R, Saxl R, Bourand A, Darbon E, Joly N, Briozzo P, Deutscher J.

Biochemistry. 2009 Jan 20;48(2):346-56. doi: 10.1021/bi8009407.


Structure of glycerol-3-phosphate dehydrogenase, an essential monotopic membrane enzyme involved in respiration and metabolism.

Yeh JI, Chinte U, Du S.

Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3280-5. doi: 10.1073/pnas.0712331105.

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